In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro CC Liang, AY Park, JL Guan Nature protocols 2 (2), 329-333, 2007 | 5155 | 2007 |
Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration CC Liang, C Wang, X Peng, B Gan, JL Guan Journal of Biological Chemistry 285 (5), 3499-3509, 2010 | 250 | 2010 |
Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region K Schlepckow, KM Monroe, G Kleinberger, L Cantuti‐Castelvetri, ... EMBO molecular medicine 12 (4), e11227, 2020 | 210 | 2020 |
FIP200 is required for maintenance and differentiation of postnatal neural stem cells C Wang, CC Liang, ZC Bian, Y Zhu, JL Guan Nature neuroscience 16 (5), 532-542, 2013 | 168 | 2013 |
TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration CC Liang, LM Tanabe, S Jou, F Chi, WT Dauer The Journal of clinical investigation 124 (7), 3080–3092, 2014 | 150 | 2014 |
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models B van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ... Nature neuroscience 26 (3), 416-429, 2023 | 107 | 2023 |
Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland T Nagy, H Wei, TL Shen, X Peng, CC Liang, B Gan, JL Guan Journal of Biological Chemistry 282 (43), 31766-31776, 2007 | 85 | 2007 |
Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model JLG Song Chen, Chenran Wang, Syn Yeo, Chun-Chi Liang, Takako Okamoto ... Genes and Development, 856-869, 2016 | 82 | 2016 |
Sustained activation of extracellular signal-regulated kinase stimulated by hepatocyte growth factor leads to integrin α2 expression that is involved in cell scattering CC Liang, HC Chen Journal of Biological Chemistry 276 (24), 21146-21152, 2001 | 78 | 2001 |
Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis PY Chu, LY Huang, CH Hsu, CC Liang, JL Guan, TH Hung, TL Shen Journal of Biological Chemistry 284 (30), 20215-20226, 2009 | 75 | 2009 |
Nuclear envelope–localized torsinA-LAP1 complex regulates hepatic VLDL secretion and steatosis JY Shin, A Hernandez-Ono, T Fedotova, C Östlund, MJ Lee, SB Gibeley, ... The Journal of clinical investigation 129 (11), 4885-4900, 2019 | 65 | 2019 |
Neuronal nuclear membrane budding occurs during a developmental window modulated by torsin paralogs LM Tanabe, CC Liang, WT Dauer Cell reports 16 (12), 3322-3333, 2016 | 60 | 2016 |
The DYT6 dystonia protein THAP1 regulates myelination within the oligodendrocyte lineage D Yellajoshyula, CC Liang, SS Pappas, S Penati, A Yang, R Mecano, ... Developmental cell 42 (1), 52-67. e4, 2017 | 59 | 2017 |
TorsinA dysfunction causes persistent neuronal nuclear pore defects SS Pappas, CC Liang, S Kim, CAO Rivera, WT Dauer Human molecular genetics 27 (3), 407-420, 2018 | 56 | 2018 |
Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum RE Goodchild, AL Buchwalter, TV Naismith, K Holbrook, K Billion, ... Journal of cell science 128 (15), 2854-2865, 2015 | 51 | 2015 |
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... Molecular neurodegeneration 17 (1), 41, 2022 | 49 | 2022 |
Synergistic effect of focal adhesion kinase overexpression and hepatocyte growth factor stimulation on cell transformation PC Chan, CC Liang, KC Yu, MC Chang, WL Ho, BH Chen, HC Chen Journal of Biological Chemistry 277 (52), 50373-50379, 2002 | 37 | 2002 |
Sensorimotor tests unmask a phenotype in the DYT1 knock-in mouse model of dystonia F Richter, J Gerstenberger, A Bauer, CC Liang, A Richter Behavioural brain research 317, 536-541, 2017 | 19 | 2017 |
TorsinB overexpression prevents abnormal twisting in DYT1 dystonia mouse models J Li, CC Liang, SS Pappas, WT Dauer Elife 9, e54285, 2020 | 18 | 2020 |
Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... bioRxiv, 2021.01. 19.426731, 2021 | 8 | 2021 |