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Brooke Bullock Lao
Brooke Bullock Lao
Pfizer
Verified email at nyu.edu
Title
Cited by
Cited by
Year
Assessing helical protein interfaces for inhibitor design
BN Bullock, AL Jochim, PS Arora
Journal of the American Chemical Society 133 (36), 14220-14223, 2011
3432011
Rational design of topographical helix mimics as potent inhibitors of protein–protein interactions
BB Lao, K Drew, DA Guarracino, TF Brewer, DW Heindel, R Bonneau, ...
Journal of the American Chemical Society 136 (22), 7877-7888, 2014
1402014
In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics
BB Lao, I Grishagin, H Mesallati, TF Brewer, BZ Olenyuk, PS Arora
Proceedings of the National Academy of Sciences 111 (21), 7531-7536, 2014
1202014
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling
S Kushal, BB Lao, LK Henchey, R Dubey, H Mesallati, NJ Traaseth, ...
Proceedings of the National Academy of Sciences 110 (39), 15602-15607, 2013
1122013
Historical changes in the distributions of invasive and endemic marine invertebrates are contrary to global warming predictions: the effects of decadal climate oscillations
TJ Hilbish, PM Brannock, KR Jones, AB Smith, BN Bullock, DS Wethey
Journal of Biogeography 37 (3), 423-431, 2010
962010
Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma
X Xie, L Piao, BN Bullock, A Smith, T Su, M Zhang, TN Teknos, PS Arora, ...
Oncogene 33 (8), 1037-1046, 2014
932014
Plucking the high hanging fruit: A systematic approach for targeting protein–protein interactions
M Raj, BN Bullock, PS Arora
Bioorganic & medicinal chemistry 21 (14), 4051-4057, 2013
842013
Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design
K Drew, PD Renfrew, TW Craven, GL Butterfoss, FC Chou, S Lyskov, ...
PLoS One 8 (7), e67051, 2013
742013
Guest-accelerated molecular rotor
BE Dial, RD Rasberry, BN Bullock, MD Smith, PJ Pellechia, S Profeta Jr, ...
Organic Letters 13 (2), 244-247, 2011
412011
Protein–protein interactions in transcription: A fertile ground for helix mimetics
DA Guarracino, BN Bullock, PS Arora
Biopolymers 95 (1), 1-7, 2011
402011
A small molecule diacid with long-term chiral memory
RD Rasberry, X Wu, BN Bullock, MD Smith, KD Shimizu
Organic letters 11 (12), 2599-2602, 2009
322009
Oligooxopiperazines and methods of making and using them
PS Arora, P Tosovska, D Guarracino, B Bullock
US Patent 8,791,121, 2014
92014
Oligooxopiperazines and methods of making and using them
PS Arora, P To, D Guarracino, BB Lao
US Patent 9,309,230, 2016
72016
Oxopiperazine helix mimetics as inhibitors of the p53-MDM2 interaction
PS Arora, BB Lao, D Guarracino, R Bonneau, K Drew
US Patent 11,180,481, 2021
52021
Oligooxopiperazines and methods of making and using them
PS Arora, P To, D Guarracino, BB Lao
US Patent 9,624,203, 2017
42017
Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics
PS Arora, BB Lao
US Patent 9,783,526, 2017
32017
Oxopiperazine helix mimetics for control of Hypoxia-Inducible gene expression
PS Arora, BB Lao, R Bonneau, K Drew
US Patent 10,787,424, 2020
12020
Oligooxopiperazines as topographical helix mimetics
BB Lao, PS Arora
Peptidomimetics II, 1-24, 2017
12017
Hydrogen bond surrogate (HBS) helices as orthosteric regulator of hypoxia inducible transcription
S Kushal, B Bullock, L Henchey, P Arora, B Olenyuk
Cancer Research 72 (8_Supplement), 289-289, 2012
12012
Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression
PS Arora, BB Lao, R Bonneau, K Drew
US Patent 11,560,359, 2023
2023
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