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Blanca Irene Aldana
Blanca Irene Aldana
University of Copehagen
Verified email at sund.ku.dk - Homepage
Title
Cited by
Cited by
Year
Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration
JV Andersen, KH Markussen, E Jakobsen, A Schousboe, ...
Neuropharmacology 196, 108719, 2021
1922021
Microglia-specific metabolic changes in neurodegeneration
BI Aldana
Journal of molecular biology 431 (9), 1830-1842, 2019
1062019
Integrative characterization of the R6/2 mouse model of Huntington’s disease reveals dysfunctional astrocyte metabolism
NH Skotte, JV Andersen, A Santos, BI Aldana, CW Willert, A Nørremølle, ...
Cell Reports 23 (7), 2211-2224, 2018
782018
Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Y Zhang, B Schmid, NK Nikolaisen, MA Rasmussen, BI Aldana, M Agger, ...
Stem cell reports 8 (3), 648-658, 2017
782017
Alterations in cerebral cortical glucose and glutamine metabolism precedes amyloid plaques in the APPswe/PSEN1dE9 mouse model of Alzheimer’s disease
JV Andersen, SK Christensen, BI Aldana, JD Nissen, H Tanila, ...
Neurochemical research 42, 1589-1598, 2017
692017
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease
JV Andersen, SK Christensen, EW Westi, M Diaz-delCastillo, H Tanila, ...
Neurobiology of disease 148, 105198, 2021
642021
The role of astrocytes in seizure generation: insights from a novel in vitro seizure model based on mitochondrial dysfunction
F Chan, NZ Lax, CM Voss, BI Aldana, S Whyte, A Jenkins, C Nicholson, ...
Brain 142 (2), 391-411, 2019
532019
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease
JV Andersen, NH Skotte, SK Christensen, FS Polli, M Shabani, ...
Cell Death & Disease 12 (11), 954, 2021
482021
Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia
BI Aldana, Y Zhang, P Jensen, A Chandrasekaran, SK Christensen, ...
Molecular Brain 13, 1-17, 2020
482020
Sertraline reduces IL-1β and TNF-α mRNA expression and overcomes their rise induced by seizures in the rat hippocampus
M Sitges, CD Gómez, BI Aldana
PLoS One 9 (11), e111665, 2014
482014
Deletion of neuronal GLT-1 in mice reveals its role in synaptic glutamate homeostasis and mitochondrial function
LF McNair, JV Andersen, BI Aldana, MC Hohnholt, JD Nissen, Y Sun, ...
Journal of Neuroscience 39 (25), 4847-4863, 2019
462019
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply
JV Andersen, EW Westi, E Jakobsen, N Urruticoechea, K Borges, ...
Molecular brain 14, 1-13, 2021
452021
Warburg effect metabolism drives neoplasia in a Drosophila genetic model of epithelial cancer
T Eichenlaub, R Villadsen, FCP Freitas, D Andrejeva, BI Aldana, ...
Current Biology 28 (20), 3220-3228. e6, 2018
452018
Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-13C]Glucose and [1,2-13C]Acetate as Substrates
LF McNair, R Kornfelt, AB Walls, JV Andersen, BI Aldana, JD Nissen, ...
Neurochemical Research 42, 810-826, 2017
382017
Functional metabolic mapping reveals highly active branched-chain amino acid metabolism in human astrocytes, which is impaired in iPSC-derived astrocytes in Alzheimer's disease
C Salcedo, JV Andersen, KT Vinten, LH Pinborg, HS Waagepetersen, ...
Frontiers in aging neuroscience 13, 736580, 2021
372021
Extensive astrocyte metabolism of γ‐aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex
JV Andersen, E Jakobsen, EW Westi, MEK Lie, CM Voss, BI Aldana, ...
Glia 68 (12), 2601-2612, 2020
362020
Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line
B Schmid, KR Prehn, N Nimsanor, BIA Garcia, U Poulsen, I Jørring, ...
Stem Cell Research 34, 101349, 2019
352019
Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non‐synaptic mouse brain mitochondria
JV Andersen, E Jakobsen, HS Waagepetersen, BI Aldana
Journal of Neuroscience Research 97 (8), 961-974, 2019
332019
Lactate-mediated protection of retinal ganglion cells
R Vohra, BI Aldana, G Bulli, DM Skytt, H Waagepetersen, LH Bergersen, ...
Journal of molecular biology 431 (9), 1878-1888, 2019
312019
Dual properties of lactate in Müller cells: the effect of GPR81 activation
R Vohra, BI Aldana, H Waagepetersen, LH Bergersen, M Kolko
Investigative ophthalmology & visual science 60 (4), 999-1008, 2019
302019
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