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Lotta Agholme
Lotta Agholme
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The
Verificeret mail på neuro.gu.se
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13150*2021
An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons
L Agholme, T Lindström, K Kågedal, J Marcusson, M Hallbeck
Journal of Alzheimer's disease 20 (4), 1069-1082, 2010
5512010
Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid
S Nath, L Agholme, FR Kurudenkandy, B Granseth, J Marcusson, ...
Journal of Neuroscience 32 (26), 8767-8777, 2012
3022012
Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17β-estradiol
J Mjösberg, J Svensson, E Johansson, L Hellström, R Casas, ...
The Journal of Immunology 183 (1), 759-769, 2009
1962009
Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance
J Domert, SB Rao, L Agholme, AC Brorsson, J Marcusson, M Hallbeck, ...
Neurobiology of disease 65, 82-92, 2014
1712014
Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer’s disease
A Armstrong, N Mattsson, H Appelqvist, C Janefjord, L Sandin, L Agholme, ...
Neuromolecular medicine 16, 150-160, 2014
1192014
Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation
P Bergström, L Agholme, FH Nazir, TM Satir, J Toombs, H Wellington, ...
Scientific reports 6 (1), 29200, 2016
932016
HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection
C Bodda, LS Reinert, S Fruhwürth, T Richardo, C Sun, B Zhang, ...
Journal of Experimental Medicine 217 (7), e20191422, 2020
712020
Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production
LS Reinert, AS Rashidi, DN Tran, G Katzilieris-Petras, AK Hvidt, M Gohr, ...
The Journal of clinical investigation 131 (1), 2021
692021
Aggregated alpha-synuclein transfer efficiently between cultured human neuron-like cells and localize to lysosomes
J Domert, C Sackmann, E Severinsson, L Agholme, J Bergström, ...
PLoS One 11 (12), e0168700, 2016
632016
Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons
WS Kim, S Bhatia, DA Elliott, L Agholme, K Kågedal, H McCann, ...
Journal of Alzheimer's Disease 21 (1), 193-205, 2010
582010
Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease
K Kågedal, WS Kim, H Appelqvist, S Chan, D Cheng, L Agholme, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010
562010
Amyloid-β secretion, generation, and lysosomal sequestration in response to proteasome inhibition: involvement of autophagy
L Agholme, M Hallbeck, E Benedikz, J Marcusson, K Kågedal
Journal of Alzheimer's disease 31 (2), 343-358, 2012
532012
Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons
TM Satir, FH Nazir, D Vizlin-Hodzic, E Hardselius, K Blennow, S Wray, ...
Scientific reports 10 (1), 601, 2020
402020
Partial reduction of amyloid β production by β-secretase inhibitors does not decrease synaptic transmission
TM Satir, L Agholme, A Karlsson, M Karlsson, P Karila, S Illes, ...
Alzheimer's Research & Therapy 12, 1-9, 2020
302020
Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons
FH Nazir, B Becker, A Brinkmalm, K Höglund, Å Sandelius, P Bergström, ...
Neurochemistry International 121, 38-49, 2018
282018
Proteasome inhibition induces stress kinase dependent transport deficits—Implications for Alzheimer's disease
L Agholme, S Nath, J Domert, J Marcusson, K Kågedal, M Hallbeck
Molecular and Cellular Neuroscience 58, 29-39, 2014
282014
Bi‐allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis‐like disease
K Sofou, K Meier, LE Sanderson, D Kaminski, L Montoliu‐Gaya, ...
EMBO molecular medicine 13 (5), e13376, 2021
172021
Tauopathy-associated tau fragment ending at amino acid 224 is generated by Calpain-2 cleavage
C Cicognola, TM Satir, G Brinkmalm, I Matečko-Burmann, L Agholme, ...
Journal of Alzheimer's Disease 74 (4), 1143-1156, 2020
92020
Herpes simplex virus 1 and 2 infections during differentiation of human cortical neurons
P Bergström, E Trybala, CE Eriksson, M Johansson, TM Satir, S Widéhn, ...
Viruses 13 (10), 2072, 2021
82021
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