| Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis B Schittek, T Sinnberg Molecular cancer 13, 1-14, 2014 | 258 | 2014 |
| Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells KG Lasithiotakis, TW Sinnberg, B Schittek, KT Flaherty, D Kulms, ... Journal of Investigative Dermatology 128 (8), 2013-2023, 2008 | 187 | 2008 |
| Vemurafenib potently induces endoplasmic reticulum stress–mediated apoptosis in BRAFV600E melanoma cells D Beck, H Niessner, KSM Smalley, K Flaherty, KHT Paraiso, C Busch, ... Science signaling 6 (260), ra7-ra7, 2013 | 172 | 2013 |
| Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide T Sinnberg, K Lasithiotakis, H Niessner, B Schittek, KT Flaherty, D Kulms, ... Journal of Investigative Dermatology 129 (6), 1500-1515, 2009 | 164 | 2009 |
| miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes C Luo, PW Tetteh, PR Merz, E Dickes, A Abukiwan, A Hotz-Wagenblatt, ... Journal of Investigative Dermatology 133 (3), 768-775, 2013 | 161 | 2013 |
| Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma–results of a prospective biomarker study A Forschner, F Battke, D Hadaschik, M Schulze, S Weißgraeber, CT Han, ... Journal for Immunotherapy of Cancer 7, 1-15, 2019 | 152 | 2019 |
| The mitogen-activated protein kinase pathway in melanoma part I–activation and primary resistance mechanisms to BRAF inhibition T Amaral, T Sinnberg, F Meier, C Krepler, M Levesque, H Niessner, ... European journal of cancer 73, 85-92, 2017 | 148 | 2017 |
| β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance T Sinnberg, M Menzel, D Ewerth, B Sauer, M Schwarz, M Schaller, ... PloS one 6 (8), e23429, 2011 | 147 | 2011 |
| Targeting hyperactivation of the AKT survival pathway to overcome therapy resistance of melanoma brain metastases H Niessner, A Forschner, B Klumpp, JB Honegger, M Witte, A Bornemann, ... Cancer medicine 2 (1), 76-85, 2013 | 144 | 2013 |
| Y-box binding protein 1–a prognostic marker and target in tumour therapy C Kosnopfel, T Sinnberg, B Schittek European journal of cell biology 93 (1-2), 61-70, 2014 | 119 | 2014 |
| Suppression of casein kinase 1α in melanoma cells induces a switch in β-catenin signaling to promote metastasis T Sinnberg, M Menzel, S Kaesler, T Biedermann, B Sauer, S Nahnsen, ... Cancer research 70 (17), 6999-7009, 2010 | 105 | 2010 |
| MAPK pathway in melanoma part II—secondary and adaptive resistance mechanisms to BRAF inhibition T Amaral, T Sinnberg, F Meier, C Krepler, M Levesque, H Niessner, ... European journal of cancer 73, 93-101, 2017 | 97 | 2017 |
| Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours E Brenner, BF Schörg, F Ahmetlić, T Wieder, FJ Hilke, N Simon, ... Nature Communications 11 (1), 1335, 2020 | 94 | 2020 |
| MAPK and PI3K/AKT mediated YB‐1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop T Sinnberg, B Sauer, P Holm, B Spangler, S Kuphal, A Bosserhoff, ... Experimental dermatology 21 (4), 265-270, 2012 | 93 | 2012 |
| Dermcidin-Derived Peptides Show a Different Mode of Action than the Cathelicidin LL-37 against Staphylococcus aureus I Senyürek, M Paulmann, T Sinnberg, H Kalbacher, M Deeg, ... Antimicrobial agents and chemotherapy 53 (6), 2499-2509, 2009 | 82 | 2009 |
| Sulforaphane protects from T cell–mediated autoimmune disease by inhibition of IL-23 and IL-12 in dendritic cells J Geisel, J Brück, I Glocova, K Dengler, T Sinnberg, O Rothfuss, M Walter, ... The Journal of Immunology 192 (8), 3530-3539, 2014 | 79 | 2014 |
| Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype T Sinnberg, MP Levesque, J Krochmann, PF Cheng, K Ikenberg, ... Molecular cancer 17, 1-19, 2018 | 76 | 2018 |
| The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells H Niessner, D Beck, T Sinnberg, K Lasithiotakis, E Maczey, J Gogel, ... Journal of Investigative Dermatology 131 (2), 468-479, 2011 | 76 | 2011 |
| PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo H Niessner, J Schmitz, G Tabatabai, AM Schmid, C Calaminus, ... Clinical Cancer Research 22 (23), 5818-5828, 2016 | 74 | 2016 |
| Sildenafil potentiates a cGMP-dependent pathway to promote melanoma growth S Dhayade, S Kaesler, T Sinnberg, H Dobrowinski, S Peters, U Naumann, ... Cell reports 14 (11), 2599-2610, 2016 | 65 | 2016 |
