| Inhibition of RAS function through targeting an allosteric regulatory site R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ... Nature Chemical Biology, 2016 | 273 | 2016 |
| Monobodies and Other Synthetic Binding Proteins for Expanding Protein Science F Sha, G Salzman, A Gupta, S Koide Protein Science, 2017 | 147 | 2017 |
| Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region GS Salzman, S Zhang, A Gupta, A Koide, S Koide, D Araç Proceedings of the National Academy of Sciences 114 (38), 10095-10100, 2017 | 68 | 2017 |
| ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation N Nady*, A Gupta*, Z Ma, T Swigut, A Koide, S Koide, J Wysocka, ... eLife, e10150, 2015 | 57 | 2015 |
| U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs JL Jenkins, AA Agrawal, A Gupta, MR Green, CL Kielkopf Nucleic Acids Research, 2013 | 51 | 2013 |
| Structure of phosphorylated SF1 bound to U2AF65 in an essential splicing factor complex W Wang, A Maucuer, A Gupta, V Manceau, KR Thickman, WJ Bauer, ... Structure 21 (2), 197-208, 2013 | 43 | 2013 |
| Facile target validation in an animal model with intracellularly expressed monobodies A Gupta, J Xu, S Lee, ST Tsai, B Zhou, K Kurosawa, MS Werner, A Koide, ... Nature chemical biology 14 (9), 895-900, 2018 | 32 | 2018 |
| Chimeric antigen receptors incorporating D domains targeting CD123 direct potent mono-and bi-specific antitumor activity of T cells H Qin, JP Edwards, L Zaritskaya, A Gupta, CJ Mu, TJ Fry, DM Hilbert, ... Molecular Therapy 27 (7), 1262-1274, 2019 | 30 | 2019 |
| Application of the “Codon-shuffling” Method A Rao, S Chopra, G Ram, A Gupta, A Ranganathan Journal of Biological Chemistry 280 (25), 23605-23614, 2005 | 20 | 2005 |
| SF1 Phosphorylation Enhances Specific Binding to U2AF65 and Reduces Binding to 3'-Splice-Site RNA R Chatrikhi, W Wang, A Gupta, S Loerch, CL Maucuer, A and Kielkopf Biophysical Journal 111, 2570–2586, 2016 | 16 | 2016 |
| RNA induces conformational changes in the SF1/U2AF65 splicing factor complex A Gupta, JL Jenkins, CL Kielkopf Journal of molecular biology 405 (5), 1128-1138, 2011 | 14 | 2011 |
| Purification, crystallization and preliminary X-ray crystallographic analysis of a central domain of human splicing factor 1 A Gupta, CL Kielkopf Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 5 | 2011 |
| Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain JM Buonato, JP Edwards, L Zaritskaya, AR Witter, A Gupta, DW LaFleur, ... Molecular Cancer Therapeutics, 2022 | 4 | 2022 |
| Novel CAR-T cell therapy that can be activated, silenced, and reprogrammed in vivo with soluble protein adapters in a dose dependent manner J Buonato, J Edwards, D LaFleur, J Swers, J Mu, L Zaritskaya, A Gupta, ... MOLECULAR THERAPY 28 (4), 346-346, 2020 | 3 | 2020 |
| Design and demonstration of potent in vitro and in vivo activity for CART ddBCMA, a BCMA targeted CAR T cell therapy incorporating a non scFv binding domain JM Buonato, J Edwards, L Zaritskaya, A Gupta, L Richman, D Hilbert, ... American Society of Gene & Cell Therapy Virtual Meeting, 11-14, 2021 | 1 | 2021 |
| Selective targeting of HER2-overexpressing solid tumors with a next-generation CAR-T cell therapy J Mu, J Edwards, L Zaritskaya, J Swers, A Gupta, D LaFleur, D Hilbert, ... J. Clin. Oncol 38 (3041), 10.1200, 2020 | 1 | 2020 |
| ACLX-001, a novel BCMA-targeted CAR-T cell therapy that can be activated, silenced, and reprogrammed in vivo with soluble protein adapters in a dose … JP Edwards, J Buonato, D LaFleur, J Swers, J Mu, L Zaritskaya, S Ng, ... Cancer Research 81 (13_Supplement), 1549-1549, 2021 | | 2021 |
| Chimeric antigen receptors incorporating novel binding domains targeting CD123 direct potent antitumor activity of T cells: Correlation between affinity and activity DW LaFleur, H Qin, JP Edwards, L Zaritskaya, A Gupta, CJ Mu, ... Cancer Research 80 (16_Supplement), 601-601, 2020 | | 2020 |
| Role of a Novel Domain in SF1/U2AF65 Complex Formation and 3' Splice Site Recognition A Gupta University of Rochester, New York, 2012 | | 2012 |
| Role of a Novel Domain in Splicing Factor 1 during the Early Stages of Pre-mRNA Splicing: 188 A Gupta, C Kielkopf Protein Science 19, 2010 | | 2010 |
Clara L. KielkopfUniversity of RochesterVerified email at urmc.rochester.edu
