Circadian control of the secretory pathway maintains collagen homeostasis J Chang, R Garva, A Pickard, CYC Yeung, V Mallikarjun, J Swift, ... Nature cell biology 22 (1), 74-86, 2020 | 148 | 2020 |
The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration M Dudek, N Yang, JPD Ruckshanthi, J Williams, E Borysiewicz, P Wang, ... Annals of the rheumatic diseases 76 (3), 576-584, 2017 | 144 | 2017 |
Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway B Guo, N Yang, E Borysiewicz, M Dudek, JL Williams, J Li, ES Maywood, ... Osteoarthritis and cartilage 23 (11), 1981-1988, 2015 | 91 | 2015 |
A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations R Jayadev, MRPT Morais, JM Ellingford, S Srinivasan, RW Naylor, ... Science Advances 8 (20), eabn2265, 2022 | 84 | 2022 |
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation CB Gurumurthy, AR O’brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ... Genome biology 20 (1), 1-14, 2019 | 81 | 2019 |
Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states A Adamson, C Boddington, P Downton, W Rowe, J Bagnall, C Lam, ... Nature communications 7 (1), 12057, 2016 | 81 | 2016 |
Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-α signaling AD Adamson, S Friedrichsen, S Semprini, CV Harper, JJ Mullins, ... Endocrinology 149 (2), 687-694, 2008 | 81 | 2008 |
A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system K Grabert, A Sehgal, KM Irvine, E Wollscheid-Lengeling, DD Ozdemir, ... The Journal of Immunology 205 (11), 3154-3166, 2020 | 62 | 2020 |
Tumor necrosis factor-α activates the human prolactin gene promoter via nuclear factor-κB signaling S Friedrichsen, CV Harper, S Semprini, M Wilding, AD Adamson, ... Endocrinology 147 (2), 773-781, 2006 | 60 | 2006 |
A human stem cell model of Fabry disease implicates LIMP-2 accumulation in cardiomyocyte pathology MJ Birket, S Raibaud, M Lettieri, AD Adamson, V Letang, P Cervello, ... Stem cell reports 13 (2), 380-393, 2019 | 59 | 2019 |
Temperature regulates NF-κB dynamics and function through timing of A20 transcription CV Harper, DJ Woodcock, C Lam, M Garcia-Albornoz, A Adamson, ... Proceedings of the National Academy of Sciences 115 (22), E5243-E5249, 2018 | 59 | 2018 |
Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation JM Ankers, R Awais, NA Jones, J Boyd, S Ryan, AD Adamson, CV Harper, ... Elife 5, e10473, 2016 | 57 | 2016 |
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation J Bagnall, C Boddington, H England, R Brignall, P Downton, Z Alsoufi, ... Science signaling 11 (540), eaaf3998, 2018 | 56 | 2018 |
Single‐cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin‐driven circadian network EL Morris, AP Patton, JE Chesham, A Crisp, A Adamson, MH Hastings The EMBO Journal 40 (20), e108614, 2021 | 54 | 2021 |
ADAMTS10-mediated tissue disruption in Weill–Marchesani syndrome EJ Mularczyk, M Singh, ARF Godwin, F Galli, N Humphreys, AD Adamson, ... Human molecular genetics 27 (21), 3675-3687, 2018 | 54 | 2018 |
Quantitative measurement of single cell dynamics D Bakstad, A Adamson, DG Spiller, MRH White Current opinion in biotechnology 23 (1), 103-109, 2012 | 45 | 2012 |
Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis J Yang, A McGovern, P Martin, K Duffus, X Ge, P Zarrineh, AP Morris, ... Nature communications 11 (1), 4402, 2020 | 44 | 2020 |
Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism AL Hunter, CE Pelekanou, A Adamson, P Downton, NJ Barron, ... Proceedings of the National Academy of Sciences 117 (41), 25869-25879, 2020 | 43 | 2020 |
Real-Time Visualization of Human Prolactin Alternate Promoter Usage in Vivo Using a Double-Transgenic Rat Model S Semprini, S Friedrichsen, CV Harper, JR McNeilly, AD Adamson, ... Molecular Endocrinology 23 (4), 529-538, 2009 | 40 | 2009 |
Adipocyte NR1D1 dictates adipose tissue expansion during obesity AL Hunter, CE Pelekanou, NJ Barron, RC Northeast, M Grudzien, ... Elife 10, e63324, 2021 | 34 | 2021 |