Phil East
Phil East
Deputy Head Bioinformatics & Biostatistics, The Francis Crick Institute
Verified email at
Cited by
Cited by
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
S Tuupanen, M Turunen, R Lehtonen, O Hallikas, S Vanharanta, T Kivioja, ...
Nature genetics 41 (8), 885-890, 2009
Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion
TR Ben-Shahar, S Heeger, C Lehane, P East, H Flynn, M Skehel, ...
Science 321 (5888), 563-566, 2008
Oncogenic RAS signaling promotes tumor immunoresistance by stabilizing PD-L1 mRNA
MA Coelho, S de Carné Trécesson, S Rana, D Zecchin, C Moore, ...
Immunity 47 (6), 1083-1099. e6, 2017
Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
C Esnault, A Stewart, F Gualdrini, P East, S Horswell, N Matthews, ...
Genes & development 28 (9), 943-958, 2014
Distinctive patterns of microRNA expression associated with karyotype in acute myeloid leukaemia
A Dixon-McIver, P East, CA Mein, JB Cazier, G Molloy, T Chaplin, ...
PloS one 3 (5), e2141, 2008
Epithelia use butyrophilin-like molecules to shape organ-specific γδ T cell compartments
RDM Barros, NA Roberts, RJ Dart, P Vantourout, A Jandke, ...
Cell 167 (1), 203-218. e17, 2016
Chromosomal instability determines taxane response
C Swanton, B Nicke, M Schuett, AC Eklund, C Ng, Q Li, T Hardcastle, ...
Proceedings of the National Academy of Sciences 106 (21), 8671-8676, 2009
The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer
MS Kumar, DC Hancock, M Molina-Arcas, M Steckel, P East, ...
Cell 149 (3), 642-655, 2012
FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression
EC Ferber, B Peck, O Delpuech, GP Bell, P East, A Schulze
Cell Death & Differentiation 19 (6), 968-979, 2012
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
B Griffiths, CA Lewis, K Bensaad, S Ros, Q Zhang, EC Ferber, S Konisti, ...
Cancer & metabolism 1, 1-21, 2013
SREBP maintains lipid biosynthesis and viability of cancer cells under lipid-and oxygen-deprived conditions and defines a gene signature associated with poor survival in …
CA Lewis, C Brault, B Peck, K Bensaad, B Griffiths, R Mitter, ...
Oncogene 34 (40), 5128-5140, 2015
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
N Moisoi, K Klupsch, V Fedele, P East, S Sharma, A Renton, ...
Cell Death & Differentiation 16 (3), 449-464, 2009
UV irradiation induces a non-coding RNA that functionally opposes the protein encoded by the same gene
L Williamson, M Saponaro, S Boeing, P East, R Mitter, T Kantidakis, ...
Cell 168 (5), 843-855. e13, 2017
Induction of Mxi1-SRα by FOXO3a Contributes to Repression of Myc-Dependent Gene Expression
O Delpuech, B Griffiths, P East, A Essafi, EWF Lam, B Burgering, ...
Molecular and cellular biology 27 (13), 4917-4930, 2007
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair
N Kanu, E Grönroos, P Martinez, RA Burrell, X Yi Goh, J Bartkova, ...
Oncogene 34 (46), 5699-5708, 2015
DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation
P Close, P East, AB Dirac-Svejstrup, H Hartmann, M Heron, S Maslen, ...
Nature 484 (7394), 386-389, 2012
RAC1P29S induces a mesenchymal phenotypic switch via serum response factor to promote melanoma development and therapy resistance
DA Lionarons, DC Hancock, S Rana, P East, C Moore, MM Murillo, ...
Cancer cell 36 (1), 68-83. e9, 2019
DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers
RN Jorissen, L Lipton, P Gibbs, M Chapman, J Desai, IT Jones, ...
Clinical cancer research 14 (24), 8061-8069, 2008
Genomic profiling identifies discrete deletions associated with translocations in glioblastoma multiforme
PJ Mulholland, H Fiegler, C Mazzanti, P Gorman, P Sasieni, J Adams, ...
Cell Cycle 5 (7), 783-791, 2006
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice
S Segditsas, O Sieber, M Deheragoda, P East, A Rowan, R Jeffery, E Nye, ...
Human molecular genetics 17 (24), 3864-3875, 2008
The system can't perform the operation now. Try again later.
Articles 1–20