Metabolic signature of extracellular vesicles depends on the cell culture conditions M Palviainen, H Saari, O Kärkkäinen, J Pekkinen, S Auriola, M Yliperttula, ... Journal of extracellular vesicles 8 (1), 1596669, 2019 | 29 | 2019 |
mGluR1/5 receptor densities in the brains of alcoholic subjects: a whole-hemisphere autoradiography study J Kupila, O Kärkkäinen, V Laukkanen, E Tupala, J Tiihonen, M Storvik Psychiatry Research: Neuroimaging 212 (3), 245-250, 2013 | 25 | 2013 |
Diets rich in whole grains increase betainized compounds associated with glucose metabolism O Kärkkäinen, MA Lankinen, M Vitale, J Jokkala, J Leppänen, V Koistinen, ... The American journal of clinical nutrition 108 (5), 971-979, 2018 | 24 | 2018 |
Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation VM Koistinen, O Kärkkäinen, K Borewicz, I Zarei, J Jokkala, V Micard, ... Microbiome 7 (1), 1-14, 2019 | 17 | 2019 |
AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: a whole-hemisphere autoradiography study O Kärkkäinen, J Kupila, M Häkkinen, V Laukkanen, E Tupala, ... Psychiatry Research: Neuroimaging 214 (3), 429-434, 2013 | 17 | 2013 |
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes O Kärkkäinen, T Tuomainen, V Koistinen, M Tuomainen, J Leppänen, ... Scientific reports 8 (1), 13036, 2018 | 15 | 2018 |
Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure O Kärkkäinen, T Tuomainen, M Mutikainen, M Lehtonen, JL Ruas, ... Cardiovascular research 115 (1), 107-118, 2019 | 14 | 2019 |
Increased metabotropic glutamate 2/3 receptor binding in the perigenual anterior cingulate cortex of Cloninger type 2 alcoholics: a whole-hemisphere autoradiography study V Laukkanen, O Kärkkäinen, J Kupila, H Kautiainen, J Tiihonen, M Storvik Alcohol and Alcoholism 50 (1), 62-67, 2015 | 12 | 2015 |
HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage S Loppi, N Kolosowska, O Kärkkäinen, P Korhonen, M Huuskonen, ... Brain, behavior, and immunity 73, 670-681, 2018 | 11 | 2018 |
Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET) M Tuomainen, O Kärkkäinen, J Leppänen, S Auriola, M Lehtonen, ... The American journal of clinical nutrition 110 (5), 1108-1118, 2019 | 10 | 2019 |
Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle‐Aged Finnish Men S Noerman, O Kärkkäinen, A Mattsson, J Paananen, M Lehtonen, T Nurmi, ... Molecular nutrition & food research 63 (5), 1800605, 2019 | 10 | 2019 |
“Notame”: Workflow for Non-Targeted LC–MS Metabolic Profiling A Klåvus, M Kokla, S Noerman, VM Koistinen, M Tuomainen, I Zarei, ... Metabolites 10 (4), 135, 2020 | 9 | 2020 |
A non-targeted LC-MS profiling reveals elevated levels of carnitine precursors and trimethylated compounds in the cord plasma of pre-eclamptic infants T Jääskeläinen, O Kärkkäinen, J Jokkala, K Litonius, S Heinonen, ... Scientific reports 8 (1), 1-12, 2018 | 9 | 2018 |
[3H] Ifenprodil binding in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study J Kupila, O Kärkkäinen, V Laukkanen, M Häkkinen, H Kautiainen, ... Psychiatry Research: Neuroimaging, 2015 | 9 | 2015 |
Decreased serum total cholesterol is associated with a history of childhood physical violence in depressed outpatients SL Kraav, T Tolmunen, O Kärkkäinen, A Ruusunen, H Viinamäki, ... Psychiatry research 272, 326-333, 2019 | 8 | 2019 |
Decreased [³H] naloxone Binding in the Dentate Gyrus of Cloninger Type 1 Anxiety‐Prone Alcoholics: A Postmortem Whole‐Hemisphere Autoradiography Study V Laukkanen, O Kärkkäinen, H Kautiainen, J Tiihonen, M Storvik Alcoholism: Clinical and Experimental Research 39 (8), 1352-1359, 2015 | 8 | 2015 |
Lower [3H] Citalopram Binding in Brain Areas Related to Social Cognition in Alcoholics O Kärkkäinen, V Laukkanen, T Haukijärvi, H Kautiainen, J Tiihonen, ... Alcohol and Alcoholism 50 (1), 46-50, 2015 | 7 | 2015 |
Changes in the serum metabolite profile correlate with decreased brain gray matter volume in moderate-to-heavy drinking young adults N Heikkinen, O Kärkkäinen, E Laukkanen, V Kekkonen, O Kaarre, ... Alcohol 75, 89-97, 2019 | 6 | 2019 |
Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics OK Kärkkäinen, M Lehtonen, V Laukkanen, E Tupala, P Hyytiä, ... Alcohol 47 (5), 399-403, 2013 | 6 | 2013 |
Alcohol and substance use are associated with altered metabolome in the first trimester serum samples of pregnant mothers AI Lehikoinen, OK Kärkkäinen, MAS Lehtonen, SOK Auriola, ... European Journal of Obstetrics & Gynecology and Reproductive Biology 223, 79-84, 2018 | 5 | 2018 |