Nicolai Juul Birkbak

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Charles SwantonFrancis Crick InstituteVerified email at crick.ac.uk
Zoltan SzallasiHarvard Medical SchoolVerified email at childrens.harvard.edu
Aron Charles EklundClinical Microbiomics A/SVerified email at clinical-microbiomics.com
Nicholas McGranahanGroup Leader, CRUK Lung Cancer Centre of Excellence, UCL Cancer InstituteVerified email at ucl.ac.uk
Andrea L RichardsonAssociate Professor of Pathology and Oncology, Johns Hopkins University School of MedicineVerified email at jhmi.edu
Hugo AertsDirector AI in Medicine (AIM) @ Harvard-MGB | Professor @ MaastrichtUVerified email at dfci.harvard.edu
Qiyuan LiSchool of Medicine, Xiamen UniversityVerified email at xmu.edu.cn
Andrew J RowanPrincipal Laboratory Research Scientist, Francis Crick InstituteVerified email at crick.ac.uk
Benjamin Haibe-KainsScientist (Principal Investigator), Princess Margaret Cancer Centre, University Health NetworkVerified email at uhnresearch.ca
John QuackenbushHarvard T.H. Chan School of Public Health, Channing Division of Network Medicine, and Dana-FarberVerified email at hsph.harvard.edu
Francesco FaveroCopenhagen UniversityVerified email at bric.ku.dk
Andrew H. BeckCo-Founder and CEO at PathAIVerified email at PathAI.com
Marcin KrzystanekAssistant Professor, Technical University of DenmarkVerified email at cbs.dtu.dk
Gareth WilsonFrancis Crick Institute, UCL Cancer InstituteVerified email at crick.ac.uk
Andrea Marion MarquardPostdoc, Technical University of DenmarkVerified email at dtu.dk
Mariam Jamal-HanjaniUCL Cancer InstituteVerified email at doctors.org.uk
Chris AbboshUniversity College LondonVerified email at ucl.ac.uk
Rebecca A BurrellUniversity of CambridgeVerified email at cruk.cam.ac.uk
Prof Marco GerlingerBarts Cancer Institute, London, UKVerified email at qmul.ac.uk
Rachel RosenthalUCLVerified email at ucl.ac.uk

Nicolai Juul Birkbak

Associate professor, Department of Molecular Medicine (MOMA), Aarhus University

Verified email at clin.au.dk - Homepage

Cancer Biology Bioinformatics Intratumor heterogeneity NGS sequencing DNA repair


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Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ... Science 351 (6280), 1463-1469, 2016	2630	2016
Tracking the evolution of non–small-cell lung cancer M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ... New England Journal of Medicine 376 (22), 2109-2121, 2017	1916	2017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017	1446	2017
Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer DP Silver, AL Richardson, AC Eklund, ZC Wang, Z Szallasi, Q Li, N Juul, ... Journal of clinical oncology 28 (7), 1145, 2010	1214	2010
Allele-specific HLA loss and immune escape in lung cancer evolution N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ... Cell 171 (6), 1259-1271. e11, 2017	941	2017
Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018	935	2018
Artificial intelligence in cancer imaging: clinical challenges and applications WL Bi, A Hosny, MB Schabath, ML Giger, NJ Birkbak, A Mehrtash, ... CA: a cancer journal for clinicians 69 (2), 127-157, 2019	906	2019
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ... The lancet oncology 18 (8), 1009-1021, 2017	753	2017
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution N McGranahan, F Favero, EC De Bruin, NJ Birkbak, Z Szallasi, ... Science translational medicine 7 (283), 283ra54-283ra54, 2015	642	2015
Neoantigen-directed immune escape in lung cancer evolution R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ... Nature 567 (7749), 479-485, 2019	604	2019
Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data F Favero, T Joshi, AM Marquard, NJ Birkbak, M Krzystanek, Q Li, ... Annals of Oncology 26 (1), 64-70, 2015	547	2015
Inconsistency in large pharmacogenomic studies B Haibe-Kains, N El-Hachem, NJ Birkbak, AC Jin, AH Beck, HJWL Aerts, ... Nature 504 (7480), 389-393, 2013	512	2013
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling SJ Song, L Poliseno, MS Song, U Ala, K Webster, C Ng, G Beringer, ... Cell 154 (2), 311-324, 2013	483	2013
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ... Cell 173 (3), 595-610. e11, 2018	473	2018
Chromosomal instability confers intrinsic multidrug resistance AJX Lee, D Endesfelder, AJ Rowan, A Walther, NJ Birkbak, PA Futreal, ... Cancer research 71 (5), 1858-1870, 2011	472	2011
Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents NJ Birkbak, ZC Wang, JY Kim, AC Eklund, Q Li, R Tian, C Bowman-Colin, ... Cancer discovery 2 (4), 366-375, 2012	470	2012
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018	449	2018
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers CM Blakely, TBK Watkins, W Wu, B Gini, JJ Chabon, CE McCoach, ... Nature genetics 49 (12), 1693-1704, 2017	413	2017
Paradoxical Relationship between Chromosomal Instability and Survival Outcome in CancerChromosomal Instability and Cancer Survival NJ Birkbak, AC Eklund, Q Li, SE McClelland, D Endesfelder, P Tan, ... Cancer research 71 (10), 3447-3452, 2011	362	2011
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ... Immunity 46 (4), 577-586, 2017	359	2017

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