Transgenerational inheritance of epigenetic states at the murine AxinFu allele occurs after maternal and paternal transmission VK Rakyan, S Chong, ME Champ, PC Cuthbert, HD Morgan, KVK Luu, ... Proceedings of the National Academy of Sciences 100 (5), 2538-2543, 2003 | 765 | 2003 |
Metastable epialleles in mammals VK Rakyan, ME Blewitt, R Druker, JI Preis, E Whitelaw Trends in Genetics 18 (7), 348-351, 2002 | 580 | 2002 |
Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses R Liu, AZ Holik, S Su, N Jansz, K Chen, HS Leong, ME Blewitt, ... Nucleic acids research 43 (15), e97-e97, 2015 | 497 | 2015 |
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation ME Blewitt, AV Gendrel, Z Pang, DB Sparrow, N Whitelaw, JM Craig, ... Nature genetics 40 (5), 663-669, 2008 | 399 | 2008 |
ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity MD Young, TA Willson, MJ Wakefield, E Trounson, DJ Hilton, ME Blewitt, ... Nucleic acids research 39 (17), 7415-7427, 2011 | 346 | 2011 |
Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice ME Blewitt, NK Vickaryous, A Paldi, H Koseki, E Whitelaw PLoS genetics 2 (4), e49, 2006 | 300 | 2006 |
An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse ME Blewitt, NK Vickaryous, SJ Hemley, A Ashe, TJ Bruxner, JI Preis, ... Proceedings of the National Academy of Sciences 102 (21), 7629-7634, 2005 | 216 | 2005 |
Modifiers of epigenetic reprogramming show paternal effects in the mouse S Chong, N Vickaryous, A Ashe, N Zamudio, N Youngson, S Hemley, ... Nature genetics 39 (5), 614-622, 2007 | 205 | 2007 |
Glimma: interactive graphics for gene expression analysis S Su, CW Law, C Ah-Cann, ML Asselin-Labat, ME Blewitt, ME Ritchie Bioinformatics 33 (13), 2050-2052, 2017 | 173 | 2017 |
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ... Nature methods 14 (11), 1055-1062, 2017 | 163 | 2017 |
Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells IJ Majewski, ME Ritchie, B Phipson, J Corbin, M Pakusch, A Ebert, ... Blood, The Journal of the American Society of Hematology 116 (5), 731-739, 2010 | 160 | 2010 |
A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development A Ashe, DK Morgan, NC Whitelaw, TJ Bruxner, NK Vickaryous, LL Cox, ... Genome biology 9, 1-16, 2008 | 142 | 2008 |
HBO1 is required for the maintenance of leukaemia stem cells L MacPherson, J Anokye, MM Yeung, EYN Lam, YC Chan, CF Weng, ... Nature 577 (7789), 266-270, 2020 | 137 | 2020 |
Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells Y Zhang, J Maksimovic, G Naselli, J Qian, M Chopin, ME Blewitt, ... Blood, The Journal of the American Society of Hematology 122 (16), 2823-2836, 2013 | 136 | 2013 |
De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development CT Gordon, S Xue, G Yigit, H Filali, K Chen, N Rosin, K Yoshiura, ... Nature genetics 49 (2), 249-255, 2017 | 133 | 2017 |
edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens Z Dai, JM Sheridan, LJ Gearing, DL Moore, S Su, S Wormald, S Wilcox, ... F1000Research 3, 2014 | 125 | 2014 |
Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity IJ Majewski, ME Blewitt, CA de Graaf, EJ McManus, M Bahlo, AA Hilton, ... PLoS biology 6 (4), e93, 2008 | 125 | 2008 |
MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML MA Sanders, E Chew, C Flensburg, A Zeilemaker, SE Miller, AS Al Hinai, ... Blood, The Journal of the American Society of Hematology 132 (14), 1526-1534, 2018 | 114 | 2018 |
Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation K Chen, J Hu, DL Moore, R Liu, SA Kessans, K Breslin, IS Lucet, A Keniry, ... Proceedings of the National Academy of Sciences 112 (27), E3535-E3544, 2015 | 111 | 2015 |
The polycomb repressive complex 2 governs life and death of peripheral T cells Y Zhang, S Kinkel, J Maksimovic, E Bandala-Sanchez, MC Tanzer, ... Blood, The Journal of the American Society of Hematology 124 (5), 737-749, 2014 | 109 | 2014 |