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Nicole Kleinstreuer
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Chronic inflammation in the etiology of disease across the life span
D Furman, J Campisi, E Verdin, P Carrera-Bastos, S Targ, C Franceschi, ...
Nature medicine 25 (12), 1822-1832, 2019
20412019
Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management
R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ...
Chemical research in toxicology 25 (7), 1287-1302, 2012
4612012
Zebrafish developmental screening of the ToxCast™ Phase I chemical library
S Padilla, D Corum, B Padnos, DL Hunter, A Beam, KA Houck, N Sipes, ...
Reproductive toxicology 33 (2), 174-187, 2012
3002012
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
2972015
Screening chemicals for estrogen receptor bioactivity using a computational model
P Browne, RS Judson, WM Casey, NC Kleinstreuer, RS Thomas
Environmental science & technology 49 (14), 8804-8814, 2015
2342015
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
2242016
Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data
NS Sipes, MT Martin, DM Reif, NC Kleinstreuer, RS Judson, AV Singh, ...
Toxicological Sciences 124 (1), 109-127, 2011
1902011
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
NC Kleinstreuer, J Yang, EL Berg, TB Knudsen, AM Richard, MT Martin, ...
Nature biotechnology 32 (6), 583-591, 2014
1782014
In vitro to in vivo extrapolation for high throughput prioritization and decision making
SM Bell, X Chang, JF Wambaugh, DG Allen, M Bartels, KLR Brouwer, ...
Toxicology in vitro 47, 213-227, 2018
1652018
T4 report: Toward good read-across practice (GRAP) guidance
N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ...
Altex 33 (2), 149, 2016
1642016
Development and validation of a computational model for androgen receptor activity
NC Kleinstreuer, P Ceger, ED Watt, M Martin, K Houck, P Browne, ...
Chemical research in toxicology 30 (4), 946-964, 2017
1592017
Integrated testing strategies (ITS) for safety assessment
C Rovida, M Daneshian, T Hartung
Alternatives to animal experimentation: ALTEX 32 (1), 25-40, 2015
1582015
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches
NC Kleinstreuer, S Hoffmann, N Alépée, D Allen, T Ashikaga, W Casey, ...
Critical reviews in toxicology 48 (5), 359-374, 2018
1462018
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
TB Knudsen, KA Houck, NS Sipes, AV Singh, RS Judson, MT Martin, ...
Toxicology 282 (1-2), 1-15, 2011
1442011
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database
S Hoffmann, N Kleinstreuer, N Alépée, D Allen, AM Api, T Ashikaga, ...
Critical reviews in toxicology 48 (5), 344-358, 2018
1342018
Environmental impact on vascular development predicted by high-throughput screening
NC Kleinstreuer, RS Judson, DM Reif, NS Sipes, AV Singh, KJ Chandler, ...
Environmental health perspectives 119 (11), 1596-1603, 2011
1272011
A computational model predicting disruption of blood vessel development
N Kleinstreuer, D Dix, M Rountree, N Baker, N Sipes, D Reif, R Spencer, ...
PLoS computational biology 9 (4), e1002996, 2013
1182013
Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics
NC Kleinstreuer, AM Smith, PR West, KR Conard, BR Fontaine, ...
Toxicology and applied pharmacology 257 (1), 111-121, 2011
1102011
In silico prediction of physicochemical properties of environmental chemicals using molecular fingerprints and machine learning
Q Zang, K Mansouri, AJ Williams, RS Judson, DG Allen, WM Casey, ...
Journal of chemical information and modeling 57 (1), 36-49, 2017
1072017
CoMPARA: collaborative modeling project for androgen receptor activity
K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ...
Environmental Health Perspectives 128 (2), 027002, 2020
1042020
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