Christian M. Metallo
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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang, K Hiller, ...
Nature 481 (7381), 380-384, 2012
13922012
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
C Commisso, SM Davidson, RG Soydaner-Azeloglu, SJ Parker, ...
Nature 497 (7451), 633-637, 2013
10542013
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
9022011
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
D Anastasiou, Y Yu, WJ Israelsen, JK Jiang, MB Boxer, BS Hong, ...
Nature chemical biology 8 (10), 839-847, 2012
5562012
Oncogenic K‐Ras decouples glucose and glutamine metabolism to support cancer cell growth
D Gaglio, CM Metallo, PA Gameiro, K Hiller, LS Danna, C Balestrieri, ...
Molecular systems biology 7 (1), 523, 2011
4182011
A roadmap for interpreting 13 C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current Opinion in Biotechnology 34, 189-201, 2015
4012015
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells
CA Lewis, SJ Parker, BP Fiske, D McCloskey, DY Gui, CR Green, ...
Molecular cell 55 (2), 253-263, 2014
4002014
Reductive carboxylation supports redox homeostasis during anchorage-independent growth
L Jiang, AA Shestov, P Swain, C Yang, SJ Parker, QA Wang, LS Terada, ...
Nature, 2016
3432016
Evaluation of 13 C isotopic tracers for metabolic flux analysis in mammalian cells
CM Metallo, JL Walther, G Stephanopoulos
Journal of biotechnology 144 (3), 167-174, 2009
2932009
Understanding metabolic regulation and its influence on cell physiology
CM Metallo, MG Vander Heiden
Molecular cell 49 (3), 388-398, 2013
2612013
Metabolic pathway alterations that support cell proliferation
MG Vander Heiden, SY Lunt, TL Dayton, BP Fiske, WJ Israelsen, ...
Cold Spring Harbor symposia on quantitative biology 76, 325-334, 2011
2452011
Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
T Valencia, JY Kim, S Abu-Baker, J Moscat-Pardos, CS Ahn, ...
Cancer cell 26 (1), 121-135, 2014
2432014
Mitochondria as biosynthetic factories for cancer proliferation
CS Ahn, CM Metallo
Cancer & metabolism 3 (1), 1-10, 2015
2372015
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
RU Svensson, SJ Parker, LJ Eichner, MJ Kolar, M Wallace, SN Brun, ...
Nature medicine 22 (10), 1108, 2016
2342016
Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
CR Green, M Wallace, AS Divakaruni, SA Phillips, AN Murphy, ...
Nature chemical biology 12 (1), 15-21, 2016
2312016
Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier
NM Vacanti, AS Divakaruni, CR Green, SJ Parker, RR Henry, TP Ciaraldi, ...
Molecular cell 56 (3), 425-435, 2014
2142014
Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels
T Cordes, M Wallace, A Michelucci, AS Divakaruni, SC Sapcariu, C Sousa, ...
Journal of Biological Chemistry 291 (27), 14274-14284, 2016
2102016
IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism
AR Grassian, SJ Parker, SM Davidson, AS Divakaruni, CR Green, ...
Cancer research 74 (12), 3317-3331, 2014
1852014
Retinoic acid and bone morphogenetic protein signaling synergize to efficiently direct epithelial differentiation of human embryonic stem cells
CM Metallo, L Ji, JJ De Pablo, SP Palecek
Stem Cells 26 (2), 372-380, 2008
1842008
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
S Zhao, AM Torres, RA Henry, S Trefely, M Wallace, JV Lee, A Carrer, ...
Cell Reports 17 (4), 1037-1052, 2016
1672016
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Artikler 1–20