Mathilde Hauge Lerche
Mathilde Hauge Lerche
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Citeret af
Increase in signal-to-noise ratio of> 10,000 times in liquid-state NMR
JH Ardenkjær-Larsen, B Fridlund, A Gram, G Hansson, L Hansson, ...
Proceedings of the National Academy of Sciences 100 (18), 10158-10163, 2003
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
SE Day, MI Kettunen, FA Gallagher, DE Hu, M Lerche, J Wolber, ...
Nature medicine 13 (11), 1382-1387, 2007
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
SE Day, MI Kettunen, FA Gallagher, DE Hu, M Lerche, J Wolber, ...
Nature medicine 13 (11), 1382-1387, 2007
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate
FA Gallagher, MI Kettunen, SE Day, DE Hu, JH Ardenkjær-Larsen, ...
Nature 453 (7197), 940-943, 2008
Metabolic Imaging by Hyperpolarized 13C Magnetic Resonance Imaging for In vivo Tumor Diagnosis
K Golman, R Zandt, M Lerche, R Pehrson, JH Ardenkjaer-Larsen
Cancer research 66 (22), 10855-10860, 2006
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors
FA Gallagher, MI Kettunen, DE Hu, PR Jensen, R Zandt, M Karlsson, ...
Proceedings of the National Academy of Sciences 106 (47), 19801-19806, 2009
Generating highly polarized nuclear spins in solution using dynamic nuclear polarization
J Wolber, F Ellner, B Fridlund, A Gram, H Johannesson, G Hansson, ...
Nuclear Instruments and Methods in Physics Research Section A: Accelerators …, 2004
13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C‐labeled glutamine
FA Gallagher, MI Kettunen, SE Day, M Lerche, KM Brindle
Magnetic Resonance in Medicine: An Official Journal of the International …, 2008
Barley lipid-transfer protein complexed with palmitoyl CoA: the structure reveals a hydrophobic binding site that can expand to fit both large and small lipid-like ligands
MH Lerche, BB Kragelund, LM Bech, FM Poulsen
Structure 5 (2), 291-306, 1997
Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides
LCB Rønn, M Olsen, S Østergaard, V Kiselyov, V Berezin, MT Mortensen, ...
Nature biotechnology 17 (10), 1000-1005, 1999
Solution structure of barley lipid transfer protein complexed with palmitate. Two different binding modes of palmitate in the homologous maize and barley nonspecific lipid …
MH Lerche, FM Poulsen
Protein Science 7 (12), 2490-2498, 1998
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes
CE Christensen, M Karlsson, JR Winther, PR Jensen, MH Lerche
Journal of Biological Chemistry 289 (4), 2344-2352, 2014
Metabolic pathway visualization in living yeast by DNP-NMR
S Meier, M Karlsson, PR Jensen, MH Lerche, JØ Duus
Molecular BioSystems 7 (10), 2834-2836, 2011
Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo
PR Jensen, T Peitersen, M Karlsson, A Gisselsson, G Hansson, S Meier, ...
Journal of Biological Chemistry 284 (52), 36077-36082, 2009
Detection of tumor glutamate metabolism in vivo using 13C magnetic resonance spectroscopy and hyperpolarized [1‐13C]glutamate
FA Gallagher, MI Kettunen, SE Day, D Hu, M Karlsson, A Gisselsson, ...
Magnetic resonance in medicine 66 (1), 18-23, 2011
Pulse sequences for measurement of one-bond 15N–1H coupling constants in the protein backbone
MH Lerche, A Meissner, FM Poulsen, OW Sørensen
Journal of Magnetic Resonance 140 (1), 259-263, 1999
Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate
M Karlsson, PR Jensen, R in't Zandt, A Gisselsson, G Hansson, JØ Duus, ...
International journal of cancer 127 (3), 729-736, 2010
Study of molecular interactions with 13C DNP-NMR
MH Lerche, S Meier, PR Jensen, H Baumann, BO Petersen, M Karlsson, ...
Journal of Magnetic Resonance 203 (1), 52-56, 2010
Hyperpolarized amino acids for in vivo assays of transaminase activity
PR Jensen, M Karlsson, S Meier, JØ Duus, MH Lerche
Chemistry–A European Journal 15 (39), 10010-10012, 2009
High-field dissolution dynamic nuclear polarization of [1-13 C] pyruvic acid
HAI Yoshihara, E Can, M Karlsson, MH Lerche, J Schwitter, A Comment
Physical Chemistry Chemical Physics 18 (18), 12409-12413, 2016
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