| Western diet triggers NLRP3-dependent innate immune reprogramming A Christ, P Günther, MAR Lauterbach, P Duewell, D Biswas, K Pelka, ... Cell 172 (1), 162-175. e14, 2018 | 819 | 2018 |
| Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics LS Ludwig, CA Lareau, JC Ulirsch, E Christian, C Muus, LH Li, K Pelka, ... Cell 176 (6), 1325-1339. e22, 2019 | 400 | 2019 |
| Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021 | 305 | 2021 |
| RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA CM Sirois, T Jin, AL Miller, D Bertheloot, H Nakamura, GL Horvath, A Mian, ... Journal of Experimental Medicine 210 (11), 2447-2463, 2013 | 227 | 2013 |
| Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess, M Gentili, ... Cell Reports Medicine 2 (5), 2021 | 190 | 2021 |
| Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling CA Lareau, LS Ludwig, C Muus, SH Gohil, T Zhao, Z Chiang, K Pelka, ... Nature biotechnology 39 (4), 451-461, 2021 | 170 | 2021 |
| OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines JL Schmid-Burgk, T Schmidt, MM Gaidt, K Pelka, E Latz, TS Ebert, ... Genome research 24 (10), 1719-1723, 2014 | 148 | 2014 |
| Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ... Cell 184 (26), 6262-6280. e26, 2021 | 147 | 2021 |
| Large-scale topological changes restrain malignant progression in colorectal cancer SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ... Cell 182 (6), 1474-1489. e23, 2020 | 141 | 2020 |
| The chaperone UNC93B1 regulates Toll-like receptor stability independently of endosomal TLR transport K Pelka, D Bertheloot, E Reimer, K Phulphagar, SV Schmidt, A Christ, ... Immunity 48 (5), 911-922. e7, 2018 | 115 | 2018 |
| Nucleic acid‐sensing TLR s and autoimmunity: novel insights from structural and cell biology K Pelka, T Shibata, K Miyake, E Latz Immunological Reviews 269 (1), 60-75, 2016 | 113 | 2016 |
| TLR8 senses bacterial RNA in human monocytes and plays a nonredundant role for recognition of Streptococcus pyogenes T Eigenbrod, K Pelka, E Latz, B Kreikemeyer, AH Dalpke The Journal of Immunology 195 (3), 1092-1099, 2015 | 97 | 2015 |
| Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming A Christ, P Gunther, MAR Lauterbach, P Duewell, D Biswas, K Pelka, ... Cell 172 (1-2), 162-175, 2018 | 91 | 2018 |
| TLR9 deficiency leads to accelerated renal disease and myeloid lineage abnormalities in pristane-induced murine lupus L Bossaller, A Christ, K Pelka, K Nündel, PI Chiang, C Pang, N Mishra, ... The Journal of Immunology 197 (4), 1044-1053, 2016 | 64 | 2016 |
| SO-26 Clinical efficacy of combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients R Corcoran, M Giannakis, J Allen, J Chen, K Pelka, S Chao, J Meyerhardt, ... Annals of Oncology 31, S226-S227, 2020 | 48 | 2020 |
| Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess, M Gentili, ... BioRxiv, 2020.11. 02.365536, 2020 | 43 | 2020 |
| The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony … J Lennartsson, H Ma, P Wardega, K Pelka, U Engström, C Hellberg, ... Journal of Biological Chemistry 288 (22), 15736-15744, 2013 | 39 | 2013 |
| IRF 5, IRF 8, and IRF 7 in human p DC s—the good, the bad, and the insignificant? K Pelka, E Latz European journal of immunology 43 (7), 1693-1697, 2013 | 37 | 2013 |
| Targeting TBK1 to overcome resistance to cancer immunotherapy Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ... Nature 615 (7950), 158-167, 2023 | 36 | 2023 |
| Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial J Tian, JH Chen, SX Chao, K Pelka, M Giannakis, J Hess, K Burke, ... Nature Medicine 29 (2), 458-466, 2023 | 36 | 2023 |
