Lucy Erin O'Brien
Lucy Erin O'Brien
Assistant Professor of Molecular and Cellular Physiology, Stanford University School of Medicine
Verified email at - Homepage
TitleCited byYear
Building epithelial architecture: insights from three-dimensional culture models
LE O'Brien, MMP Zegers, KE Mostov
Nature reviews Molecular cell biology 3 (7), 531, 2002
Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly
LE O'Brien, TS Jou, AL Pollack, Q Zhang, SH Hansen, P Yurchenco, ...
Nature cell biology 3 (9), 831, 2001
β1-integrin orients epithelial polarity via Rac1 and laminin
W Yu, A Datta, P Leroy, LE O'Brien, G Mak, TS Jou, KS Matlin, KE Mostov, ...
Molecular biology of the cell 16 (2), 433-445, 2005
Altered modes of stem cell division drive adaptive intestinal growth
LE O'Brien, SS Soliman, X Li, D Bilder
Cell 147 (3), 603-614, 2011
Epithelial polarity and tubulogenesis in vitro
MMP Zegers, LE O'Brien, W Yu, A Datta, KE Mostov
Trends in cell biology 13 (4), 169-176, 2003
ERK and MMPs sequentially regulate distinct stages of epithelial tubule development
LE O'Brien, K Tang, ES Kats, A Schutz-Geschwender, JH Lipschutz, ...
Developmental cell 7 (1), 21-32, 2004
Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins
JH Lipschutz, W Guo, LE O'Brien, YH Nguyen, P Novick, KE Mostov
Molecular Biology of the Cell 11 (12), 4259-4275, 2000
Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures
W Yu, LE O'Brien, F Wang, H Bourne, KE Mostov, MMP Zegers
Molecular biology of the cell 14 (2), 748-763, 2003
Morphological and Biochemical Analysis of Rac1 in Three‐Dimensional Epithelial Cell Cultures
LE O'Brien, W Yu, K Tang, TS Jou, MMP Zegers, KE Mostov
Methods in enzymology 406, 676-691, 2006
Beyond the niche: tissue-level coordination of stem cell dynamics
LE O'Brien, D Bilder
Annual review of cell and developmental biology 29, 107-136, 2013
Feedback regulation of steady-state epithelial turnover and organ size
J Liang, S Balachandra, S Ngo, LE O’Brien
Nature 548 (7669), 588, 2017
Analysis of membrane traffic in polarized epithelial cells
JH Lipschutz, LE O'Brien, Y Altschuler, D Avrahami, Y Nguyen, K Tang, ...
Current protocols in cell biology 12 (1), 15.5. 1-15.5. 18, 2001
STAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesis
M Kim, LE O'Brien, SH Kwon, KE Mostov
Molecular biology of the cell 21 (22), 3926-3933, 2010
Regional specificity in the Drosophila midgut: setting boundaries with stem cells
LE O’Brien
Cell stem cell 13 (4), 375-376, 2013
Formation of multicellular epithelial structures
K Mostov, P Brakeman, A Datta, A Gassama, L Katz, M Kim, P Leroy, ...
Novartis Found Symp 269, 193-200, 2005
Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss
JL Martin, EN Sanders, P Moreno-Roman, LAJ Koyama, S Balachandra, ...
eLife 7, e36248, 2018
Microfluidics for mechanobiology of model organisms
AA Kim, AL Nekimken, S Fechner, LE O’Brien, BL Pruitt
Methods in cell biology 146, 217-259, 2018
Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of cell division, differentiation, and loss
J Martin, EN Sanders, P Moreno-Roman, S Balachandra, XX Du, ...
bioRxiv, 271742, 2018
A model for adult organ resizing demonstrates stem cell scaling through a tunable commitment rate
XX Du, LE O’Brien, IH Riedel-Kruse
Biophysical journal 113 (1), 174-184, 2017
Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila
LAJ Koyama, A Aranda-Díaz, YH Su, S Balachandra, JL Martin, ...
bioRxiv, 741991, 2019
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