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Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans N Mende, HP Bastos, A Santoro, KT Mahbubani, V Ciaurro, ... Blood, The Journal of the American Society of Hematology 139 (23), 3387-3401, 2022 | 32 | 2022 |
IL-3-zetakine combined with a CD33 costimulatory receptor as a dual CAR approach for safer and selective targeting of AML VM Perriello, MC Rotiroti, I Pisani, S Galimberti, G Alberti, G Pianigiani, ... Blood Advances 7 (12), 2855-2871, 2023 | 7 | 2023 |
CD123 and CD33 co-targeting by balanced signaling on CAR-CIK cells reduces potential off-target toxicity while preserving the anti-leukemic activity of acute myeloid leukemia VM Perriello, MC Rotiroti, I Pisani, G Alberti, G Pianigiani, R Rossi, ... Blood 138, 1699, 2021 | 5 | 2021 |
Synergistic growth inhibition of NPM1 mutant AML PDX by combined therapy with BCL-2 inhibitor venetoclax (ABT-199) and menin inhibitor DS-1594b in vivo V Ciaurro, MY Konopleva, N Daver, A Skwarska, MP Martelli Blood 142, 4169, 2023 | 1 | 2023 |
Tuned IL3-Zetakine coupled to a CD33 costimulatory receptor as a dual CAR for safer and selective targeting of acute myeloid leukemia VM Perriello, MC Rotiroti, I Pisani, S Galimberti, G Alberti, G Pianigiani, ... Blood 140 (Supplement 1), 10237-10238, 2022 | 1 | 2022 |
Menin Inhibitor DS-1594b Drives Differentiation and Induces Synergistic Lethality in Combination with Venetoclax in AML Cells with MLL-Rearranged and NPM1 Mutation V Ciaurro, A Skwarska, N Daver, M Konopleva Blood 140 (Supplement 1), 3082-3083, 2022 | | 2022 |
ISOCITRATE DEHYDROGENASES AML-ASSOCIATED POINT MUTATIONS DRIVE A BLOCK OF DIFFERENTIATION IN HUMAN NORMAL CD34+ HEMATOPOIETIC CELLS THAT IS RELEASED BY SPECIFIC INHIBITORS S Pierangeli, V Ciaurro, S Donnini, F Milano, M Sabino, I Gionfriddo, ... HAEMATOLOGICA 107, 50-50, 2022 | | 2022 |
CORRECTION OF THE DNMT3A MUTATION IN OCI-AML3 HARBOURING DNMT3AR882C MUTATION AND NPM1 MUTATION A DOES NOT AFFECT LEUKEMIA SURVIVAL AND GROWTH IN VITRO AND IN VIVO F Milano, C Quadalti, LA Giovinati, S Pierangeli, M Sabino, R Ranieri, ... HAEMATOLOGICA 107, 17-18, 2022 | | 2022 |
IDH1-R132H EXPRESSION DRIVES IN HUMAN NORMAL CD34+ HEMATOPOIETIC CELLS A BLOCK OF DIFFERENTIATION RELEASED BY THE SPECIFIC INHIBITOR IVOSIDENIB V Ciaurro, S Pierangeli, B Falini, MP Martelli HAEMATOLOGICA 105, S25-S26, 2020 | | 2020 |
STEM CELL LIKE ERYTHROID/MEGAKARYOCYTE-PRIMED PROGENITORS EXPAND IN HUMANS IN RESPONSE TO FREQUENT PLATELET DONATION N Mende, V Ciaurro, A Santoro, E Calderbank, L Hellequin, T Morishima, ... Experimental Hematology 76, S55, 2019 | | 2019 |