Neil T. Umbreit
Neil T. Umbreit
Dana-Farber Cancer Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B
JF Tien, NT Umbreit, DR Gestaut, AD Franck, J Cooper, L Wordeman, ...
Journal of Cell Biology 189 (4), 713-723, 2010
1752010
The Ndc80 kinetochore complex directly modulates microtubule dynamics
NT Umbreit, DR Gestaut, JF Tien, BS Vollmar, T Gonen, CL Asbury, ...
Proceedings of the National Academy of Sciences 109 (40), 16113-16118, 2012
1022012
The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling
A Zelter, M Bonomi, J ook Kim, NT Umbreit, MR Hoopmann, R Johnson, ...
Nature communications 6, 8673, 2015
372015
Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation
NT Umbreit, MP Miller, JF Tien, JC Ortolá, L Gui, KK Lee, S Biggins, ...
Nature communications 5 (1), 1-11, 2014
362014
Regulation of outer kinetochore Ndc80 complex-based microtubule attachments by the central kinetochore Mis12/MIND complex
EM Kudalkar, EA Scarborough, NT Umbreit, A Zelter, DR Gestaut, M Riffle, ...
Proceedings of the National Academy of Sciences 112 (41), E5583-E5589, 2015
332015
The Ndc80 complex bridges two Dam1 complex rings
J ook Kim, A Zelter, NT Umbreit, A Bollozos, M Riffle, R Johnson, ...
Elife 6, e21069, 2017
282017
The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling
S Viswanath, M Bonomi, SJ Kim, VA Klenchin, KC Taylor, KC Yabut, ...
Molecular biology of the cell 28 (23), 3298-3314, 2017
222017
Coupling unbiased mutagenesis to high-throughput DNA sequencing uncovers functional domains in the Ndc80 kinetochore protein of Saccharomyces cerevisiae
JF Tien, KK Fong, NT Umbreit, C Payen, A Zelter, CL Asbury, MJ Dunham, ...
Genetics 195 (1), 159-170, 2013
202013
Kinetochore biorientation in Saccharomyces cerevisiae requires a tightly folded conformation of the Ndc80 complex
JF Tien, NT Umbreit, A Zelter, M Riffle, MR Hoopmann, RS Johnson, ...
Genetics 198 (4), 1483-1493, 2014
172014
Mitosis puts sisters in a strained relationship: force generation at the kinetochore
NT Umbreit, TN Davis
Experimental cell research 318 (12), 1361-1366, 2012
102012
Cancer biology: Genome jail-break triggers lockdown
NT Umbreit, D Pellman
Nature 550 (7676), 340-341, 2017
52017
Mechanisms Generating Cancer Genome Complexity From A Single Cell Division Error
N Umbreit, CZ Zhang, LD Lynch, LJ Blaine, AM Cheng, RW Tourdot, ...
bioRxiv, 835058, 2019
32019
Cell Biology: when your own chromosomes act like foreign DNA
A Spektor, NT Umbreit, D Pellman
Current Biology 27 (22), R1228-R1231, 2017
22017
Human Nuclear RNAi-Defective 2 (NRDE2) is an essential RNA splicing factor
AL Jiao, R Perales, NT Umbreit, JR Haswell, ME Piper, BD Adams, ...
RNA 25 (3), 352-363, 2019
12019
A Bayesian Integrative Structure Model of the Yeast Centrosome
S Viswanath, M Bonomi, SJ Kim, VA Klenchin, K Taylor, KC Yabut, ...
Biophysical Journal 114 (3), 35a, 2018
2018
ORC is not essential for DNA replication in human cell lines, but important for repressing Rb-E2F and Polycomb group regulated genes.
A Spektor, C Zhang, N Umbreit, M Feldman, A Ahsan, Y Zhang, ...
MOLECULAR BIOLOGY OF THE CELL 27, 2016
2016
DNA damage and chromothripsis from chromosome segregation errors.
A Spektor, Z Cheng-Zhong, NT Umbreit, H Cornils, JM Francis, ...
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
Regulation of Ndc80-based microtubule attachments by the central kinetochore Mis12/MIND complex suggests a folding-based molecular mechanism
EA Scarborough, EM Kudalkar, N Umbreit, J Tien, CL Asbury, E Muller, ...
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
A mechanism for chromosome bridge resolution based on nuclear envelope fragility and DNA damage
NT Umbreit, A Spektor, Z Cheng-Zhong, M Leibowitz, JM Francis, ...
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
Reconstitution of strong kinetochore attachments requires more than the microtubule binding components.
EM Kudalkar, N Umbreit, D Gestaut, EA Scarborough, C Asbury, T Davis
MOLECULAR BIOLOGY OF THE CELL 25, 2014
2014
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Articles 1–20