| Vinyl Sulfide Cyclized Analogues of Angiotensin II with High Affinity and Full Agonist Activity at the AT1 Receptor P Johannesson, G Lindeberg, A Johansson, GV Nikiforovich, A Gogoll, ... Journal of medicinal chemistry 45 (9), 1767-1777, 2002 | 150 | 2002 |
| Making medicinal chemistry more effective—application of Lean Sigma to improve processes, speed and quality S Andersson, A Armstrong, A Björe, S Bowker, S Chapman, R Davies, ... Drug discovery today 14 (11-12), 598-604, 2009 | 82 | 2009 |
| Discovery of second generation reversible covalent DPP1 inhibitors leading to an oxazepane amidoacetonitrile based clinical candidate (AZD7986) K Doyle, H Lönn, H Käck, A Van de Poël, S Swallow, P Gardiner, ... Journal of Medicinal Chemistry 59 (20), 9457-9472, 2016 | 62 | 2016 |
| Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic acid bioisostere N Pemberton, H Graden, E Evertsson, E Bratt, M Lepistö, ... ACS Medicinal Chemistry Letters 3 (7), 574-578, 2012 | 56 | 2012 |
| Bicyclic tripeptide mimetics with reverse turn inducing properties P Johannesson, G Lindeberg, W Tong, A Gogoll, A Karlén, A Hallberg Journal of medicinal chemistry 42 (4), 601-608, 1999 | 51 | 1999 |
| Involvement of the metabolic sensor GPR81 in cardiovascular control K Wallenius, P Thalén, JA Björkman, P Johannesson, J Wiseman, ... JCI insight 2 (19), 2017 | 42 | 2017 |
| Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide … JG Barlind, UA Bauer, AM Birch, S Birtles, LK Buckett, RJ Butlin, ... Journal of medicinal chemistry 55 (23), 10610-10629, 2012 | 42 | 2012 |
| Therapeutic Agents-550 RJ Butlin, PWR Caulkett, P Johannesson, LD Knerr, A Leach, ... US Patent App. 11/961,850, 2009 | 38 | 2009 |
| Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats C Bengtsson, S Blaho, DB Saitton, K Brickmann, J Broddefalk, ... Bioorganic & medicinal chemistry 19 (10), 3039-3053, 2011 | 36 | 2011 |
| Angiotensin II analogues encompassing 5, 9-and 5, 10-fused thiazabicycloalkane tripeptide mimetics P Johannesson, G Lindeberg, W Tong, A Gogoll, B Synnergren, F Nyberg, ... Journal of medicinal chemistry 42 (22), 4524-4537, 1999 | 32 | 1999 |
| AT2-selective angiotensin II analogues containing tyrosine-functionalized 5, 5-bicyclic thiazabicycloalkane dipeptide mimetics P Johannesson, M Erdélyi, G Lindeberg, PA Frändberg, F Nyberg, ... Journal of medicinal chemistry 47 (24), 6009-6019, 2004 | 31 | 2004 |
| Carbamoyl compounds as DGAT1 inhibitors 190 P Johannesson, JM Johansson, AU Petersson, AM Birch, RJ Butlin US Patent 7,994,179, 2011 | 23 | 2011 |
| Discovery of AZD4831, a mechanism-based irreversible inhibitor of myeloperoxidase, as a potential treatment for heart failure with preserved ejection fraction T Inghardt, T Antonsson, C Ericsson, D Hovdal, P Johannesson, ... Journal of Medicinal Chemistry 65 (17), 11485-11496, 2022 | 19 | 2022 |
| Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl … M Munck af Rosenschöld, P Johannesson, A Nikitidis, C Tyrchan, ... Journal of Medicinal Chemistry 62 (17), 7769-7787, 2019 | 17 | 2019 |
| New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus-087 D Blomberg, A Holmen, P Johannesson, P Sorme, P Stahlberg, ... US Patent App. 12/339,600, 2009 | 10 | 2009 |
| M. Le Gr ves, F. Nyberg, A. KarlØn, A. Hallberg P Johannesson, G Lindeberg, A Johansson, GV Nikiforovich, A Gogoll, ... J. Med. Chem 45, 1767-1777, 2002 | 7 | 2002 |
| Identification of novel GPR81 agonist lead series for target biology evaluation Ö Davidsson, K Nilsson, J Brånalt, T Andersson, K Berggren, Y Chen, ... Bioorganic & Medicinal Chemistry Letters 30 (4), 126953, 2020 | 6 | 2020 |
| 1-[2-(aminomethyl) benzyl]-2-thioxo-1, 2, 3, 5-tetrahydro-4h-pyrrolo [3, 2-d] pyrimidin-4-ones as inhibitors of myeloperoxidase TB Inghardt, P Johannesson, U Jurva, EL Lindstedt-Alstermark, ... US Patent 9,616,063, 2017 | 6 | 2017 |
| Synthesis of Brensocatib (AZD7986) P Johannesson J. Med. Chem 59, 9457-9472, 2016 | 2 | 2016 |
| 1-[2-(aminomethyl) benzyl]-2-thioxo-1, 2, 3, 5-tetrahydro-4H-pyrrolo [3, 2-d] pyrimidin-4-ones as inhibitors of myeloperoxidase TB Inghardt, P Johannesson, U Jurva, E Michaelsson, ... US Patent 10,016,430, 2018 | 1 | 2018 |
