Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines W Song, S Wei, Y Zhou, A Lazrak, G Liu, JD Londino, GL Squadrito, ... Journal of biological chemistry 285 (13), 9716-9728, 2010 | 60 | 2010 |
Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection JD Londino, A Lazrak, JW Noah, S Aggarwal, V Bali, BA Woodworth, ... The FASEB Journal 29 (7), 2712, 2015 | 54 | 2015 |
Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity JS Bednash, N Weathington, J Londino, M Rojas, DL Gulick, R Fort, ... Nature communications 8 (1), 15203, 2017 | 53 | 2017 |
Influenza virus infection alters ion channel function of airway and alveolar cells: mechanisms and physiological sequelae JD Londino, A Lazrak, JF Collawn, Z Bebok, KS Harrod, S Matalon American Journal of Physiology-Lung Cellular and Molecular Physiology 313 (5 …, 2017 | 52 | 2017 |
Cleavage of signal regulatory protein α (SIRPα) enhances inflammatory signaling JD Londino, D Gulick, JS Isenberg, RK Mallampalli Journal of Biological Chemistry 290 (52), 31113-31125, 2015 | 47 | 2015 |
Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling JS Bednash, VE Kagan, JA Englert, D Farkas, YY Tyurina, VA Tyurin, ... Translational Research 240, 1-16, 2022 | 44 | 2022 |
Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity JD Londino, A Lazrak, A Jurkuvenaite, JF Collawn, JW Noah, S Matalon American Journal of Physiology-Lung Cellular and Molecular Physiology 304 (9 …, 2013 | 41 | 2013 |
The deubiquitinase STAMBP modulates cytokine secretion through the NLRP3 inflammasome JS Bednash, F Johns, N Patel, TR Smail, JD Londino, RK Mallampalli Cellular signalling 79, 109859, 2021 | 38 | 2021 |
Post-translational modification of the interferon-gamma receptor alters its stability and signaling JD Londino, DL Gulick, TB Lear, TL Suber, NM Weathington, LS Masa, ... Biochemical Journal 474 (20), 3543-3557, 2017 | 31 | 2017 |
Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling G Apriamashvili, DW Vredevoogd, O Krijgsman, OB Bleijerveld, ... Nature communications 13 (1), 1923, 2022 | 27 | 2022 |
FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells TL Suber, I Nikolli, ME O’Brien, J Londino, J Zhao, K Chen, ... Respiratory research 19, 1-11, 2018 | 27 | 2018 |
The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunity Y Tong, TB Lear, J Evankovich, Y Chen, JD Londino, MM Myerburg, ... JCI insight 5 (3), 2020 | 22 | 2020 |
Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation J Evankovich, T Lear, A Mckelvey, S Dunn, J Londino, Y Liu, BB Chen, ... The FASEB Journal 31 (9), 3894, 2017 | 21 | 2017 |
RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity AC McKelvey, TB Lear, SR Dunn, J Evankovich, JD Londino, JS Bednash, ... Elife 5, e18496, 2016 | 21 | 2016 |
Interferon lambda signaling in macrophages is necessary for the antiviral response to influenza RK Mallampalli, J Adair, A Elhance, D Farkas, L Chafin, ME Long, M De, ... Frontiers in immunology 12, 735576, 2021 | 17 | 2021 |
Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter ME O’Brien, J Londino, M McGinnis, N Weathington, J Adair, T Suber, ... Molecular and Cellular Biology 40 (12), e00040-20, 2020 | 15 | 2020 |
Toll-like receptor 8 stability is regulated by ring finger 216 in response to circulating microRNAs J Evankovich, T Lear, C Baldwin, Y Chen, V White, J Villandre, J Londino, ... American journal of respiratory cell and molecular biology 62 (2), 157-167, 2020 | 15 | 2020 |
KIAA0317 regulates pulmonary inflammation through SOCS2 degradation TB Lear, AC McKelvey, JW Evankovich, S Rajbhandari, TA Coon, ... JCI insight 4 (19), 2019 | 15 | 2019 |
MicroID2: a novel biotin ligase enables rapid proximity-dependent proteomics BS Johnson, L Chafin, D Farkas, J Adair, A Elhance, L Farkas, ... Molecular & Cellular Proteomics 21 (7), 2022 | 11 | 2022 |
The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis D Chandra, J Londino, S Alexander, JS Bednash, Y Zhang, ... Journal of molecular and cellular cardiology 126, 50-59, 2019 | 11 | 2019 |