Calmodulin mutations associated with recurrent cardiac arrest in infants L Crotti, CN Johnson, E Graf, GM De Ferrari, BF Cuneo, M Ovadia, ... Circulation 127 (9), 1009-1017, 2013 | 413 | 2013 |
ETAA1 acts at stalled replication forks to maintain genome integrity TE Bass, JW Luzwick, G Kavanaugh, C Carroll, H Dungrawala, GG Glick, ... Nature cell biology 18 (11), 1185-1195, 2016 | 257 | 2016 |
Structural and energetic determinants of apo calmodulin binding to the IQ motif of the NaV1. 2 voltage-dependent sodium channel MD Feldkamp, L Yu, MA Shea Structure 19 (5), 733-747, 2011 | 103 | 2011 |
Discovery of a potent inhibitor of replication protein a protein–protein interactions using a fragment-linking approach AO Frank, MD Feldkamp, JP Kennedy, AG Waterson, NF Pelz, JD Patrone, ... Journal of medicinal chemistry 56 (22), 9242-9250, 2013 | 71 | 2013 |
Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozyme JH Lee, A Pardi Nucleic acids research 35 (9), 2965-2974, 2007 | 66 | 2007 |
Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A AO Frank, B Vangamudi, MD Feldkamp, EM Souza-Fagundes, ... Journal of medicinal chemistry 57 (6), 2455-2461, 2014 | 61 | 2014 |
HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells Q Li, JJ Cooper, GH Altwerger, MD Feldkamp, MA Shea, DH Price Nucleic acids research 35 (8), 2503-2512, 2007 | 58 | 2007 |
Effects of human deafness γ-actin mutations (DFNA20/26) on actin function KE Bryan, KK Wen, M Zhu, ND Rendtorff, M Feldkamp, L Tranebjaerg, ... Journal of biological chemistry 281 (29), 20129-20139, 2006 | 50 | 2006 |
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A EM Souza-Fagundes, AO Frank, MD Feldkamp, DC Dorset, WJ Chazin, ... Analytical biochemistry 421 (2), 742-749, 2012 | 46 | 2012 |
Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1 MD Feldkamp, AC Mason, BF Eichman, WJ Chazin Biochemistry 53 (18), 3052-3061, 2014 | 44 | 2014 |
Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin MD Feldkamp, SE O'Donnell, L Yu, MA Shea Proteins: Structure, Function, and Bioinformatics 78 (10), 2265-2282, 2010 | 38 | 2010 |
Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected … B Bernat, M Sun, M Dwyer, M Feldkamp, AA Kossiakoff Biochemistry 43 (20), 6076-6084, 2004 | 32 | 2004 |
Discovery of protein–protein interaction inhibitors of replication protein A JD Patrone, JP Kennedy, AO Frank, MD Feldkamp, B Vangamudi, ... ACS medicinal chemistry letters 4 (7), 601-605, 2013 | 29 | 2013 |
Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1. 2 L Hovey, CA Fowler, R Mahling, Z Lin, MS Miller, DC Marx, JB Yoder, ... Biophysical chemistry 224, 1-19, 2017 | 26 | 2017 |
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein MD Feldkamp, AO Frank, JP Kennedy, JD Patrone, B Vangamudi, ... Biochemistry 52 (37), 6515-6524, 2013 | 23 | 2013 |
Identification and optimization of anthranilic acid based inhibitors of replication protein A JD Patrone, NF Pelz, BS Bates, EM Souza‐Fagundes, B Vangamudi, ... ChemMedChem 11 (8), 893-899, 2016 | 17 | 2016 |
Diphenylpyrazoles as replication protein a inhibitors AG Waterson, JP Kennedy, JD Patrone, NF Pelz, MD Feldkamp, AO Frank, ... ACS Medicinal Chemistry Letters 6 (2), 140-145, 2015 | 17 | 2015 |
Opposing orientations of the anti‐psychotic drug trifluoperazine selected by alternate conformations of M 144 in calmodulin MD Feldkamp, L Gakhar, N Pandey, MA Shea Proteins: Structure, Function, and Bioinformatics 83 (5), 989-996, 2015 | 13 | 2015 |
NMR studies of the interaction of calmodulin with IQ motif peptides SM Damo, MD Feldkamp, B Chagot, WJ Chazin Calcium-Binding Proteins and RAGE: From Structural Basics to Clinical …, 2013 | 9 | 2013 |
Simian virus Large T antigen interacts with the N-terminal domain of the 70 kD subunit of Replication Protein A in the same mode as multiple DNA damage response factors B Ning, MD Feldkamp, D Cortez, WJ Chazin, KL Friedman, E Fanning PLoS One 10 (2), e0116093, 2015 | 8 | 2015 |