Bryan Greenhagen
Bryan Greenhagen
Founder Mystic Brewrey
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Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases
BT Greenhagen, PE O’Maille, JP Noel, J Chappell
Proceedings of the National Academy of Sciences 103 (26), 9826-9831, 2006
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
PE O'maille, A Malone, N Dellas, BA Hess, L Smentek, I Sheehan, ...
Nature chemical biology 4 (10), 617-623, 2008
Metabolic engineering of sesquiterpene metabolism in yeast
S Takahashi, Y Yeo, BT Greenhagen, T McMullin, L Song, ...
Biotechnology and bioengineering 97 (1), 170-181, 2007
Structural and Functional Analysis of the Pyocyanin Biosynthetic Protein PhzM from Pseudomonas aeruginosa,
JF Parsons, BT Greenhagen, K Shi, K Calabrese, H Robinson, JE Ladner
Biochemistry 46 (7), 1821-1828, 2007
Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio-and stereo-specific hydroxylations of diverse sesquiterpene substrates
S Takahashi, YS Yeo, Y Zhao, PE O'Maille, BT Greenhagen, JP Noel, ...
Journal of Biological Chemistry 282 (43), 31744-31754, 2007
Crystal structure of the pyocyanin biosynthetic protein PhzS
BT Greenhagen, K Shi, H Robinson, S Gamage, AK Bera, JE Ladner, ...
Biochemistry 47 (19), 5281-5289, 2008
Molecular scaffolds for chemical wizardry: learning nature's rules for terpene cyclases
B Greenhagen, J Chappell
Proceedings of the National Academy of Sciences 98 (24), 13479-13481, 2001
Kinetic and molecular analysis of 5-epiaristolochene 1, 3-dihydroxylase, a cytochrome P450 enzyme catalyzing successive hydroxylations of sesquiterpenes
S Takahashi, Y Zhao, PE O'Maille, BT Greenhagen, JP Noel, RM Coates, ...
Journal of Biological Chemistry 280 (5), 3686-3696, 2005
Surrogate splicing for functional analysis of sesquiterpene synthase genes
S Wu, MA Schoenbeck, BT Greenhagen, S Takahashi, S Lee, RM Coates, ...
Plant physiology 138 (3), 1322-1333, 2005
Sesquiterpene synthase gene and protein
J Chappell, B Greenhagen
US Patent 7,442,785, 2008
Probing sesquiterpene hydroxylase activities in a coupled assay with terpene synthases
BT Greenhagen, P Griggs, S Takahashi, L Ralston, J Chappell
Archives of biochemistry and biophysics 409 (2), 385-394, 2003
Gene library synthesis by structure-based combinatorial protein engineering
PE O'Maille, MD Tsai, BT Greenhagen, J Chappell, JP Noel
Methods in enzymology 388, 75-91, 2004
Methods for Splicing Plant Genes
J Chappell, M Schoenbeck, B Greenhagen
US Patent App. 11/610,733, 2007
Surgical diseases of the colon and rectum in small animals
K Pratschke
In Practice 27 (7), 354-362, 2005
Origins of isoprenoid diversity: A study of structure-function relationships in sesquiterpene synthases
BT Greenhagen
University of Kentucky, 2003
Unraveling the catalytic specificity of terpene biosynthetic enzymes and engineering the biosynthesis of novel terpenes in yeast and plants
J Chappell, S Wu, S Takahashi, B Greenhagen
In Vitro Cellular & Developmental Biology-Animal 44, S27-S27, 2008
Chapter ten The chemical wizardry of isoprenoid metabolism in plants
BT Greenhagen, MA Schoenbeck, YS Yeo, J Chappell
Recent Advances in Phytochemistry 37, 231-251, 2003
Sesquiterpene Synthase Gene and Protein
J Chappell, BT Greenhagen
Engineering terpene synthases for novel product specificity
BT Greenhagen, YX Zhao, P O'Maille, J Noel, RM Coates, J Chappell
FASEB JOURNAL 17 (5), A978-A978, 2003
Dissecting the chemical wizardry of terpene synthases
BT Greenhagen, J Chappell
FASEB JOURNAL 16 (5), A896-A896, 2002
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