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Ivan Merelli
Ivan Merelli
Researcher in Bioinformatics, Institute for Biomedical Technologies
Verificeret mail på itb.cnr.it
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Precise gene editing preserves hematopoietic stem cell function following transient p53-mediated DNA damage response
G Schiroli, A Conti, S Ferrari, L Della Volpe, A Jacob, L Albano, S Beretta, ...
Cell stem cell 24 (4), 551-565. e8, 2019
2852019
Managing, analysing, and integrating big data in medical bioinformatics: open problems and future perspectives
I Merelli, H Pérez-Sánchez, S Gesing, D D’Agostino
BioMed research international 2014 (1), 134023, 2014
2302014
Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking
S Ferrari, A Jacob, S Beretta, G Unali, L Albano, V Vavassori, D Cittaro, ...
Nature biotechnology 38 (11), 1298-1308, 2020
1472020
A multilevel data integration resource for breast cancer study
E Mosca, R Alfieri, I Merelli, F Viti, A Calabria, L Milanesi
BMC systems biology 4, 1-11, 2010
1162010
HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells
D Cesana, FR Santoni de Sio, L Rudilosso, P Gallina, A Calabria, ...
Nature communications 8 (1), 498, 2017
1062017
StreamFlow: cross-breeding cloud with HPC
I Colonnelli, B Cantalupo, I Merelli, M Aldinucci
IEEE Transactions on Emerging Topics in Computing, 2020
872020
RSSsite: a reference database and prediction tool for the identification of cryptic Recombination Signal Sequences in human and murine genomes
I Merelli, A Guffanti, M Fabbri, A Cocito, L Furia, U Grazini, RJ Bonnal, ...
Nucleic acids research 38 (suppl_2), W262-W267, 2010
842010
Genotoxic effects of base and prime editing in human hematopoietic stem cells
M Fiumara, S Ferrari, A Omer-Javed, S Beretta, L Albano, D Canarutto, ...
Nature biotechnology 42 (6), 877-891, 2024
812024
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells
S Ferrari, A Jacob, D Cesana, M Laugel, S Beretta, A Varesi, G Unali, ...
Cell Stem Cell 29 (10), 1428-1444. e9, 2022
742022
Grid-Enabled High-Throughput In Silico Screening Against Influenza A Neuraminidase
HC Lee, J Salzemann, N Jacq, HY Chen, LY Ho, I Merelli, L Milanesi, ...
IEEE transactions on nanobioscience 5 (4), 288-295, 2006
742006
Molecular mechanism of allosteric communication in Hsp70 revealed by molecular dynamics simulations
F Chiappori, I Merelli, G Colombo, L Milanesi, G Morra
PLoS computational biology 8 (12), e1002844, 2012
652012
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes
AMS Giordano, M Luciani, F Gatto, M Abou Alezz, C Beghè, L Della Volpe, ...
Journal of Experimental Medicine 219 (4), e20211121, 2022
612022
DnaK as antibiotic target: hot spot residues analysis for differential inhibition of the bacterial protein in comparison with the human HSP70
F Chiappori, M Fumian, L Milanesi, I Merelli
PloS one 10 (4), e0124563, 2015
552015
Virtual screening on large scale grids
N Jacq, V Breton, HY Chen, LY Ho, M Hofmann, V Kasam, HC Lee, ...
Parallel Computing 33 (4-5), 289-301, 2007
552007
An atomistic view of Hsp70 allosteric crosstalk: from the nucleotide to the substrate binding domain and back
F Chiappori, I Merelli, L Milanesi, G Colombo, G Morra
Scientific Reports 6 (1), 23474, 2016
472016
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models
F Birocchi, M Cusimano, F Rossari, S Beretta, PMV Rancoita, A Ranghetti, ...
Science translational medicine 14 (653), eabl4106, 2022
462022
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome
V Vavassori, E Mercuri, GE Marcovecchio, MC Castiello, G Schiroli, ...
EMBO Molecular Medicine 13 (3), e13545, 2021
452021
Durable and efficient gene silencing in vivo by hit-and-run epigenome editing
MA Cappelluti, V Mollica Poeta, S Valsoni, P Quarato, S Merlin, I Merelli, ...
Nature 627 (8003), 416-423, 2024
442024
Combining edge and cloud computing for low-power, cost-effective metagenomics analysis
D D’Agostino, L Morganti, E Corni, D Cesini, I Merelli
Future Generation Computer Systems 90, 79-85, 2019
442019
Cloud Infrastructures for In Silico Drug Discovery: Economic and Practical Aspects
D D′ Agostino, A Clematis, A Quarati, D Cesini, F Chiappori, L Milanesi, ...
BioMed Research International 2013 (1), 138012, 2013
422013
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Artikler 1–20