Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth P Zhang, A Singh, S Yegnasubramanian, D Esopi, P Kombairaju, ... Molecular cancer therapeutics 9 (2), 336-346, 2010 | 431 | 2010 |
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice TE Sussan, T Rangasamy, DJ Blake, D Malhotra..., MS Yates, ... Proceedings of the National Academy of Sciences 106 (1), 250-255, 2009 | 380 | 2009 |
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis X Kong, R Thimmulappa, F Craciun, C Harvey, A Singh, P Kombairaju, ... American journal of respiratory and critical care medicine 184 (8), 928-938, 2011 | 226 | 2011 |
NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice X Kong, R Thimmulappa, P Kombairaju, S Biswal The Journal of Immunology 185 (1), 569-577, 2010 | 201 | 2010 |
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients D Malhotra, RK Thimmulappa, N Mercado, K Ito, P Kombairaju, S Kumar, ... The Journal of clinical investigation 121 (11), 4289-4302, 2011 | 165 | 2011 |
Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia–reperfusion injury Y Wei, J Gong, T Yoshida, CG Eberhart, Z Xu, P Kombairaju, MB Sporn, ... Free Radical Biology and Medicine 51 (1), 216-224, 2011 | 155 | 2011 |
Deletion of Keap1 in the lung attenuates acute cigarette smoke–induced oxidative stress and inflammation DJ Blake, A Singh, P Kombairaju, D Malhotra, TJ Mariani, RM Tuder, ... American journal of respiratory cell and molecular biology 42 (5), 524-536, 2010 | 153 | 2010 |
NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation JH Kim, RK Thimmulappa, V Kumar, W Cui, S Kumar, P Kombairaju, ... The Journal of clinical investigation 124 (2), 730-741, 2014 | 130 | 2014 |
Knockout of the transcription factor Nrf2: Effects on testosterone production by aging mouse Leydig cells H Chen, S Jin, J Guo, P Kombairaju, S Biswal, BR Zirkin Molecular and cellular endocrinology 409, 113-120, 2015 | 66 | 2015 |
Pinhole castration: a novel minimally invasive technique for in situ spermatic cord ligation KS Ponvijay Veterinary surgery 36 (1), 74-79, 2007 | 35 | 2007 |
Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle P Kombairaju, JP Kerr, JA Roche, SJP Pratt, RM Lovering, TE Sussan, ... Frontiers in physiology 5, 57, 2014 | 27 | 2014 |
Prolonged sulforaphane treatment does not enhance tumorigenesis in oncogenic K-ras and xenograft mouse models of lung cancer P Kombairaju, J Ma, RK Thimmulappa, SG Yan, E Gabrielson, A Singh, ... Journal of Carcinogenesis 11, 2012 | 18 | 2012 |
A mouse model for Luminal epithelial like ER positive subtype of human breast cancer MJM Kumar, KS Ponvijay, R Nandhini, RS Nagarajan, J Jose, G Srinivas, ... BMC cancer 7 (1), 180, 2007 | 14 | 2007 |
Targeting NRF2 Activation Modulates X-Ros Signaling in Dystrophic Skeletal Muscle CW Ward, JP Kerr, P Kombairaju, TE Sussan, SJP Pratt, RM Lovering, ... Biophysical Journal 106 (2), 727a, 2014 | | 2014 |
Tamoxifen-resistant, ER-positive MAC 51 cell line with a high metastatic potential developed from a spontaneous breast cancer mouse model. OT Kumar JM, Kombairaju P, Nagarajan P, Subramanian T Cell Tissue Research, 2012 | | 2012 |