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Ponvijay Kombairaju
Ponvijay Kombairaju
Assistant Scientist , Johns Hopkins University
Verificeret mail på jhsph.edu
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Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth
P Zhang, A Singh, S Yegnasubramanian, D Esopi, P Kombairaju, ...
Molecular cancer therapeutics 9 (2), 336-346, 2010
4312010
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
TE Sussan, T Rangasamy, DJ Blake, D Malhotra..., MS Yates, ...
Proceedings of the National Academy of Sciences 106 (1), 250-255, 2009
3802009
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis
X Kong, R Thimmulappa, F Craciun, C Harvey, A Singh, P Kombairaju, ...
American journal of respiratory and critical care medicine 184 (8), 928-938, 2011
2262011
NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice
X Kong, R Thimmulappa, P Kombairaju, S Biswal
The Journal of Immunology 185 (1), 569-577, 2010
2012010
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients
D Malhotra, RK Thimmulappa, N Mercado, K Ito, P Kombairaju, S Kumar, ...
The Journal of clinical investigation 121 (11), 4289-4302, 2011
1652011
Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia–reperfusion injury
Y Wei, J Gong, T Yoshida, CG Eberhart, Z Xu, P Kombairaju, MB Sporn, ...
Free Radical Biology and Medicine 51 (1), 216-224, 2011
1552011
Deletion of Keap1 in the lung attenuates acute cigarette smoke–induced oxidative stress and inflammation
DJ Blake, A Singh, P Kombairaju, D Malhotra, TJ Mariani, RM Tuder, ...
American journal of respiratory cell and molecular biology 42 (5), 524-536, 2010
1532010
NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation
JH Kim, RK Thimmulappa, V Kumar, W Cui, S Kumar, P Kombairaju, ...
The Journal of clinical investigation 124 (2), 730-741, 2014
1302014
Knockout of the transcription factor Nrf2: Effects on testosterone production by aging mouse Leydig cells
H Chen, S Jin, J Guo, P Kombairaju, S Biswal, BR Zirkin
Molecular and cellular endocrinology 409, 113-120, 2015
662015
Pinhole castration: a novel minimally invasive technique for in situ spermatic cord ligation
KS Ponvijay
Veterinary surgery 36 (1), 74-79, 2007
352007
Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle
P Kombairaju, JP Kerr, JA Roche, SJP Pratt, RM Lovering, TE Sussan, ...
Frontiers in physiology 5, 57, 2014
272014
Prolonged sulforaphane treatment does not enhance tumorigenesis in oncogenic K-ras and xenograft mouse models of lung cancer
P Kombairaju, J Ma, RK Thimmulappa, SG Yan, E Gabrielson, A Singh, ...
Journal of Carcinogenesis 11, 2012
182012
A mouse model for Luminal epithelial like ER positive subtype of human breast cancer
MJM Kumar, KS Ponvijay, R Nandhini, RS Nagarajan, J Jose, G Srinivas, ...
BMC cancer 7 (1), 180, 2007
142007
Targeting NRF2 Activation Modulates X-Ros Signaling in Dystrophic Skeletal Muscle
CW Ward, JP Kerr, P Kombairaju, TE Sussan, SJP Pratt, RM Lovering, ...
Biophysical Journal 106 (2), 727a, 2014
2014
Tamoxifen-resistant, ER-positive MAC 51 cell line with a high metastatic potential developed from a spontaneous breast cancer mouse model.
OT Kumar JM, Kombairaju P, Nagarajan P, Subramanian T
Cell Tissue Research, 2012
2012
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Artikler 1–15