Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders D Pietra, S Li, A Brisci, F Passamonti, E Rumi, A Theocharides, M Ferrari, ... Blood, The Journal of the American Society of Hematology 111 (3), 1686-1689, 2008 | 417 | 2008 |
Leukemic blasts in transformed JAK2-V617F–positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation. A Theocharides, M Boissinot, F Girodon, R Garand, SS Teo, E Lippert, ... Blood, The Journal of the American Society of Hematology 110 (1), 375-379, 2007 | 383 | 2007 |
Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders R Kralovics, SS Teo, S Li, A Theocharides, AS Buser, A Tichelli, ... Blood 108 (4), 1377-1380, 2006 | 343 | 2006 |
Humanized hemato-lymphoid system mice APA Theocharides, A Rongvaux, K Fritsch, RA Flavell, MG Manz Haematologica 101 (1), 5, 2016 | 191 | 2016 |
Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts APA Theocharides, L Jin, PY Cheng, TK Prasolava, AV Malko, JM Ho, ... Journal of experimental medicine 209 (10), 1883-1899, 2012 | 164 | 2012 |
Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations S Li, R Kralovics, G De Libero, A Theocharides, H Gisslinger, RC Skoda Blood, The Journal of the American Society of Hematology 111 (7), 3863-3866, 2008 | 140 | 2008 |
Deliberate removal of T cell help improves virus-neutralizing antibody production M Recher, KS Lang, L Hunziker, S Freigang, B Eschli, NL Harris, ... Nature immunology 5 (9), 934-942, 2004 | 111 | 2004 |
Angiogenesis and vascular endothelial growth factor‐/receptor expression in myeloproliferative neoplasms: correlation with clinical parameters and JAK2‐V617F mutational status M Medinger, R Skoda, A Gratwohl, A Theocharides, A Buser, D Heim, ... British journal of haematology 146 (2), 150-157, 2009 | 106 | 2009 |
IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms LF Mager, C Riether, CM Schürch, Y Banz, MH Wasmer, R Stuber, ... The Journal of clinical investigation 125 (7), 2579-2591, 2015 | 103 | 2015 |
Candida albicans-Induced NETosis Is Independent of Peptidylarginine Deiminase 4 E Guiducci, C Lemberg, N Küng, E Schraner, APA Theocharides, ... Frontiers in immunology 9, 1573, 2018 | 97 | 2018 |
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ... Cancer Cell 39 (3), 288-293, 2021 | 89 | 2021 |
Extralymphatic virus sanctuaries as a consequence of potent T-cell activation M Recher, KS Lang, A Navarini, L Hunziker, PA Lang, K Fink, S Freigang, ... Nature medicine 13 (11), 1316-1323, 2007 | 70 | 2007 |
The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders A Theocharides, JR Passweg, M Medinger, R Looser, S Li, H Hao-Shen, ... Haematologica 93 (12), 1890-1893, 2008 | 50 | 2008 |
The IL‐6 signaling complex is a critical driver, negative prognostic factor, and therapeutic target in diffuse large B‐cell lymphoma H Hashwah, K Bertram, K Stirm, A Stelling, CT Wu, S Kasser, MG Manz, ... EMBO molecular medicine 11 (10), e10576, 2019 | 48 | 2019 |
Sensitive Quantitative Proteomics of Human Hematopoietic Stem and Progenitor Cells by Data-independent Acquisition Mass Spectrometry*[S] S Amon, F Meier-Abt, LC Gillet, S Dimitrieva, APA Theocharides, ... Molecular & Cellular Proteomics 18 (7), 1454-1467, 2019 | 48 | 2019 |
inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice JM Ellegast, PJ Rauch, LV Kovtonyuk, R Müller, U Wagner, Y Saito, ... Blood, The Journal of the American Society of Hematology 128 (17), 2130-2134, 2016 | 45 | 2016 |
Homozygous calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency APA Theocharides, P Lundberg, AKK Lakkaraju, V Lysenko, R Myburgh, ... Blood, The Journal of the American Society of Hematology 127 (25), 3253-3259, 2016 | 43 | 2016 |
Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts APA Theocharides, SM Dobson, E Laurenti, F Notta, V Voisin, PY Cheng, ... Leukemia 29 (1), 177-187, 2015 | 34 | 2015 |
The sympathomimetic agonist mirabegron did not lower JAK2-V617F allele burden, but restored nestin-positive cells and reduced reticulin fibrosis in patients with … B Drexler, JR Passweg, A Tzankov, M Bigler, APA Theocharides, ... Haematologica 104 (4), 710, 2019 | 33 | 2019 |
Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t (13; 13)(q12; q22) involving FLT3 A Tzankov, K Sotlar, D Muhlematter, A Theocharides, P Went, M Jotterand, ... Journal of clinical pathology 61 (8), 958-961, 2008 | 30 | 2008 |