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Poul Henning Jensen
Poul Henning Jensen
Professor of medical biochemistry, Aarhus university
Verificeret mail på biokemi.au.dk
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Structural and functional characterization of two alpha-synuclein strains
L Bousset, L Pieri, G Ruiz-Arlandis, J Gath, PH Jensen, B Habenstein, ...
Nature communications 4 (1), 2575, 2013
8932013
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease
Z Hong, M Shi, KA Chung, JF Quinn, ER Peskind, D Galasko, J Jankovic, ...
Brain 133 (3), 713-726, 2010
7242010
Binding of α-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation
PH Jensen, MS Nielsen, R Jakes, CG Dotti, M Goedert
Journal of Biological Chemistry 273 (41), 26292-26294, 1998
6891998
Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase. plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin …
A Nykjær, CM Petersen, B Møller, PH Jensen, SK Moestrup, TL Holtet, ...
Journal of Biological Chemistry 267 (21), 14543-14546, 1992
6001992
Proteasomal inhibition by α-synuclein filaments and oligomers
E Lindersson, R Beedholm, P Højrup, T Moos, WP Gai, KB Hendil, ...
Journal of Biological Chemistry 279 (13), 12924-12934, 2004
5062004
α-Synuclein binds to tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356
PH Jensen, H Hager, MS Nielsen, P Højrup, J Gliemann, R Jakes
Journal of Biological Chemistry 274 (36), 25481-25489, 1999
4651999
Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo
E Colla, PH Jensen, O Pletnikova, JC Troncoso, C Glabe, MK Lee
Journal of Neuroscience 32 (10), 3301-3305, 2012
3672012
In situ and in vitro study of colocalization and segregation of α-synuclein, ubiquitin, and lipids in Lewy bodies
WP Gai, HX Yuan, XQ Li, JTH Power, PC Blumbergs, PH Jensen
Experimental neurology 166 (2), 324-333, 2000
3182000
Phosphorylated α-synuclein in Parkinson’s disease
Y Wang, M Shi, KA Chung, CP Zabetian, JB Leverenz, D Berg, K Srulijes, ...
Science translational medicine 4 (121), 121ra20-121ra20, 2012
3132012
Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats
N Van Den Berge, N Ferreira, H Gram, TW Mikkelsen, AKO Alstrup, ...
Acta neuropathologica 138 (4), 535-550, 2019
2592019
Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies
KE Paleologou, CL Kragh, DMA Mann, SA Salem, R Al-Shami, D Allsop, ...
Brain 132 (4), 1093-1101, 2009
2542009
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo
E Rockenstein, S Nuber, CR Overk, K Ubhi, M Mante, C Patrick, A Adame, ...
Brain 137 (5), 1496-1513, 2014
2462014
α-Synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease
GM Halliday, A Ophof, M Broe, PH Jensen, E Kettle, H Fedorow, ...
Brain 128 (11), 2654-2664, 2005
2322005
Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion
P Ejlerskov, I Rasmussen, TT Nielsen, AL Bergström, Y Tohyama, ...
Journal of Biological Chemistry 288 (24), 17313-17335, 2013
2282013
How Epigallocatechin Gallate Can Inhibit α-Synuclein Oligomer Toxicity in Vitro♦
N Lorenzen, SB Nielsen, Y Yoshimura, BS Vad, CB Andersen, C Betzer, ...
Journal of Biological Chemistry 289 (31), 21299-21310, 2014
2162014
Calcium (II) selectively induces α‐synuclein annular oligomers via interaction with the C‐terminal domain
R Lowe, DL Pountney, PH Jensen, WP Gai, NH Voelcker
Protein Science 13 (12), 3245-3252, 2004
2112004
p25α stimulates α-synuclein aggregation and is co-localized with aggregated α-synuclein in α-synucleinopathies
E Lindersson, D Lundvig, C Petersen, P Madsen, JR Nyengaard, ...
Journal of Biological Chemistry 280 (7), 5703-5715, 2005
2042005
p25α relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy
YJC Song, DMS Lundvig, Y Huang, WP Gai, PC Blumbergs, P Højrup, ...
The American journal of pathology 171 (4), 1291-1303, 2007
1992007
Ca2+ binding to α-synuclein regulates ligand binding and oligomerization
MS Nielsen, H Vorum, E Lindersson, PH Jensen
Journal of Biological Chemistry 276 (25), 22680-22684, 2001
1992001
Binding of Aβ to α- and β-synucleins: identification of segments in α-synuclein/NAC precursor that bind Aβ and NAC
PH JENSEN, P HØJRUP, H HAGER, MS NIELSEN, L JACOBSEN, ...
Biochemical Journal 323 (2), 539-546, 1997
1911997
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Artikler 1–20