| Single-Nucleotide Polymorphisms (SNP) Mining and Their Effect on the Tridimensional Protein Structure Prediction in a Set of Immunity-Related Expressed Sequence Tags (EST) in … E Vallejos-Vidal, S Reyes-Cerpa, JA Rivas-Pardo, K Maisey, JM Yáñez, ... Frontiers in Genetics 10, 1406, 2020 | 47 | 2020 |
| Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism … JA Rivas-Pardo, A Herrera-Morande, V Castro-Fernandez, FJ Fernandez, ... PLoS One 8 (6), e66687, 2013 | 32 | 2013 |
| Bifunctional ADP‐dependent phosphofructokinase/glucokinase activity in the order M ethanococcales–biochemical characterization of the mesophilic enzyme from M ethanococcus … V Castro‐Fernandez, F Bravo‐Moraga, A Herrera‐Morande, V Guixe The FEBS journal 281 (8), 2017-2029, 2014 | 22 | 2014 |
| Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases V Castro-Fernandez, A Herrera-Morande, R Zamora, F Merino, ... Journal of Biological Chemistry 292 (38), 15598-15610, 2017 | 19 | 2017 |
| Expression and localization of an agmatinase-like protein in the rat brain C Mella, F Martínez, M de los Angeles García, F Nualart, V Castro, ... Histochemistry and cell biology 134, 137-144, 2010 | 18 | 2010 |
| Emergence of pyridoxal phosphorylation through a promiscuous ancestor during the evolution of hydroxymethyl pyrimidine kinases V Castro-Fernandez, F Bravo-Moraga, CA Ramirez-Sarmiento, V Guixe FEBS letters 588 (17), 3068-3073, 2014 | 14 | 2014 |
| Evolution, Metabolism and Molecular Mechanisms Underlying Extreme Adaptation of Euryarchaeota and Its Biotechnological Potential V Castro‐Fernandez, R Zamora, A Herrera‐Morande, G Vallejos, ... Archaea-New Biocatalysts, Novel Pharmaceuticals and Various Biotechnological …, 2017 | 13 | 2017 |
| Crystal Structure of Escherichia coli Agmatinase: Catalytic Mechanism and Residues Relevant for Substrate Specificity P Maturana, MS Orellana, SM Herrera, I Martínez, M Figueroa, ... International Journal of Molecular Sciences 22 (9), 4769, 2021 | 11 | 2021 |
| Characterization of hydroxymethylpyrimidine phosphate kinase from mesophilic and thermophilic bacteria and structural insights into their differential thermal stability PA Cea, G Araya, G Vallejos, R Recabarren, J Alzate-Morales, J Babul, ... Archives of biochemistry and biophysics 688, 108389, 2020 | 11 | 2020 |
| Evidence for an inhibitory LIM domain in a rat brain agmatinase-like protein V Castro, P Fuentealba, A Henríquez, A Vallejos, J Benítez, M Lobos, ... Archives of biochemistry and biophysics 512 (1), 107-110, 2011 | 11 | 2011 |
| ADP-dependent kinases from the archaeal order Methanosarcinales adapt to salt by a non-canonical evolutionarily conserved strategy F Gonzalez-Ordenes, PA Cea, N Fuentes-Ugarte, SM Muñoz, RA Zamora, ... Frontiers in microbiology 9, 1305, 2018 | 9 | 2018 |
| Protein topology determines substrate-binding mechanism in homologous enzymes A Herrera-Morande, V Castro-Fernández, F Merino, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (12), 2869-2878, 2018 | 8 | 2018 |
| Structural and functional analysis of the ASM p. Ala359Asp mutant that causes acid sphingomyelinase deficiency M Acuña, V Castro-Fernández, M Latorre, J Castro, EH Schuchman, ... Biochemical and biophysical research communications 479 (3), 496-501, 2016 | 8 | 2016 |
| Tuning of Conformational Dynamics Through Evolution-Based Design Modulates the Catalytic Adaptability of an Extremophilic Kinase RA Zamora, CA Ramirez-Sarmiento, V Castro-Fernandez, P Villalobos, ... ACS Catalysis 10 (19), 10847-10857, 2020 | 7 | 2020 |
| ADP-dependent phosphofructokinases from the archaeal order Methanosarcinales display redundant glucokinase activity RA Zamora, F Gonzalez-Órdenes, V Castro-Fernández, V Guixé Archives of biochemistry and biophysics 633, 85-92, 2017 | 7 | 2017 |
| Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds: the fluorescence of the … RA Zamora, E Fuentes-Lemus, P Barrias, A Herrera-Morande, F Mura, ... Free Radical Biology and Medicine 150, 40-52, 2020 | 6 | 2020 |
| Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes SM Muñoz, V Castro-Fernandez, V Guixé Journal of Biological Chemistry 296, 100219, 2021 | 5 | 2021 |
| Crystal structure and molecular dynamics simulations of a promiscuous ancestor reveal residues and an epistatic interaction involved in substrate binding and catalysis in the … F Gonzalez‐Ordenes, F Bravo‐Moraga, E Gonzalez, ... Protein Science 30 (4), 842-854, 2021 | 3 | 2021 |
| Unusual dimerization of a BcCsp mutant leads to reduced conformational dynamics AI Carvajal, G Vallejos, EA Komives, V Castro‐Fernández, DA Leonardo, ... The FEBS journal 284 (12), 1882-1896, 2017 | 3 | 2017 |
| The Emergence of New Catalytic Abilities in an Endoxylanase from Family GH10 by Removing an Intrinsically Disordered Region C Gil-Durán, RV Sepúlveda, M Rojas, V Castro-Fernández, V Guixé, ... International Journal of Molecular Sciences 23 (4), 2315, 2022 | 2 | 2022 |
