| Engineering stem cell organoids X Yin, BE Mead, H Safaee, R Langer, JM Karp, O Levy Cell stem cell 18 (1), 25-38, 2016 | 814 | 2016 |
| Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells D Zhang, W Jiang, M Liu, X Sui, X Yin, S Chen, Y Shi, H Deng Cell research 19 (4), 429-438, 2009 | 774 | 2009 |
| Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells Z Song, J Cai, Y Liu, D Zhao, J Yong, S Duo, X Song, Y Guo, Y Zhao, ... Cell research 19 (11), 1233-1242, 2009 | 629 | 2009 |
| Two supporting factors greatly improve the efficiency of human iPSC generation Y Zhao, X Yin, H Qin, F Zhu, H Liu, W Yang, Q Zhang, C Xiang, P Hou, ... Cell stem cell 3 (5), 475-479, 2008 | 626 | 2008 |
| Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny X Yin, HF Farin, JH Van Es, H Clevers, R Langer, JM Karp Nature methods 11 (1), 106-112, 2014 | 568 | 2014 |
| Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules Y Li, Q Zhang, X Yin, W Yang, Y Du, P Hou, J Ge, C Liu, W Zhang, ... Cell research 21 (1), 196-204, 2011 | 402 | 2011 |
| Neutralizing antibodies in patients with severe acute respiratory syndrome-associated coronavirus infection N Yuchun, W Guangwen, S Xuanling, Z Hong, Q Yan, H Zhongping, ... The Journal of infectious diseases 190 (6), 1119-1126, 2004 | 190 | 2004 |
| Clonal expansion of Lgr5-positive cells from mammalian cochlea and high-purity generation of sensory hair cells WJ McLean, X Yin, L Lu, DR Lenz, D McLean, R Langer, JM Karp, ... Cell reports 18 (8), 1917-1929, 2017 | 189 | 2017 |
| Expression cloning of functional receptor used by SARS coronavirus P Wang, J Chen, A Zheng, Y Nie, X Shi, W Wang, G Wang, M Luo, H Liu, ... Biochemical and biophysical research communications 315 (2), 439-444, 2004 | 181 | 2004 |
| Identification of an antigenic determinant on the S2 domain of the severe acute respiratory syndrome coronavirus spike glycoprotein capable of inducing neutralizing antibodies H Zhang, G Wang, J Li, Y Nie, X Shi, G Lian, W Wang, X Yin, Y Zhao, X Qu, ... Journal of virology 78 (13), 6938-6945, 2004 | 168 | 2004 |
| Triggerable tough hydrogels for gastric resident dosage forms J Liu, Y Pang, S Zhang, C Cleveland, X Yin, L Booth, J Lin, YA Lucy Lee, ... Nature communications 8 (1), 124, 2017 | 138 | 2017 |
| Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein K Yuan, L Yi, J Chen, X Qu, T Qing, X Rao, P Jiang, J Hu, Z Xiong, Y Nie, ... Biochemical and biophysical research communications 319 (3), 746-752, 2004 | 128 | 2004 |
| Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression Y Nie, P Wang, X Shi, G Wang, J Chen, A Zheng, W Wang, Z Wang, X Qu, ... Biochemical and biophysical research communications 321 (4), 994-1000, 2004 | 127 | 2004 |
| Application of biomaterials to advance induced pluripotent stem cell research and therapy Z Tong, A Solanki, A Hamilos, O Levy, K Wen, X Yin, JM Karp The EMBO journal 34 (8), 987-1008, 2015 | 104 | 2015 |
| Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease FEO Holmberg, JB Seidelin, X Yin, BE Mead, Z Tong, Y Li, JM Karp, ... EMBO molecular medicine 9 (5), 558-570, 2017 | 79 | 2017 |
| Induction of neutralizing antibody against human immunodeficiency virus type 1 (HIV-1) by immunization with gp41 membrane-proximal external region (MPER) fused with porcine … M Luo, F Yuan, Y Liu, S Jiang, X Song, P Jiang, X Yin, M Ding, H Deng Vaccine 24 (4), 435-442, 2006 | 55 | 2006 |
| Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells Z Tong, K Martyn, A Yang, X Yin, BE Mead, N Joshi, NE Sherman, ... Biomaterials 154, 60-73, 2018 | 46 | 2018 |
| Method and kit for efficient reprogramming of somatic cells H Deng, Y Zhao, X Yin, Q Zhang, F Zhu, H Liu, W Yang, C Xiang, H Qin US Patent App. 12/568,634, 2010 | 44 | 2010 |
| Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types BE Mead, J Ordovas-Montanes, AP Braun, LE Levy, P Bhargava, ... BMC biology 16, 1-24, 2018 | 43 | 2018 |
| Robust differentiation of human enteroendocrine cells from intestinal stem cells D Zeve, E Stas, J de Sousa Casal, P Mannam, W Qi, X Yin, S Dubois, ... Nature communications 13 (1), 261, 2022 | 25 | 2022 |
Jeffrey M. KarpProfessor of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Harvard-MITVerified email at partners.org
