| Molecular pharmacological phenotyping of EBI2: an orphan seven-transmembrane receptor with constitutive activity MM Rosenkilde, T Benned-Jensen, H Andersen, PJ Holst, TN Kledal, ... Journal of Biological Chemistry 281 (19), 13199-13208, 2006 | 136 | 2006 |
| The minor binding pocket: a major player in 7TM receptor activation MM Rosenkilde, T Benned-Jensen, TM Frimurer, TW Schwartz Trends in pharmacological sciences 31 (12), 567-574, 2010 | 119 | 2010 |
| Distinct expression and ligand‐binding profiles of two constitutively active GPR17 splice variants T Benned‐Jensen, MM Rosenkilde British journal of pharmacology 159 (5), 1092-1105, 2010 | 84 | 2010 |
| Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: ablation of constitutive signaling is associated with an attenuated phenotype in vivo R Case, E Sharp, T Benned-Jensen, MM Rosenkilde, N Davis-Poynter, ... Journal of virology 82 (4), 1884-1898, 2008 | 60 | 2008 |
| Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist T Benned-Jensen, C Smethurst, PJ Holst, KR Page, H Sauls, B Sivertsen, ... Journal of Biological Chemistry 286 (33), 29292-29302, 2011 | 58 | 2011 |
| Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183) T Benned-Jensen, C Norn, S Laurent, CM Madsen, HM Larsen, KN Arfelt, ... Journal of Biological Chemistry 287 (42), 35470-35483, 2012 | 50 | 2012 |
| Oxysterol‐EBI2 signaling in immune regulation and viral infection V Daugvilaite, KN Arfelt, T Benned‐Jensen, AW Sailer, MM Rosenkilde European Journal of Immunology 44 (7), 1904-1912, 2014 | 44 | 2014 |
| The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling T Benned-Jensen, J Mokrosinski, MM Rosenkilde PLoS One 6 (9), e24644, 2011 | 43 | 2011 |
| Live imaging of Kv7. 2/7.3 cell surface dynamics at the axon initial segment: high steady-state stability and calpain-dependent excitotoxic downregulation revealed T Benned-Jensen, RK Christensen, F Denti, JF Perrier, HB Rasmussen, ... Journal of Neuroscience 36 (7), 2261-2266, 2016 | 42 | 2016 |
| Small molecule antagonism of oxysterol-induced Epstein–Barr virus induced gene 2 (EBI2) activation T Benned-Jensen, CM Madsen, KN Arfelt, C Smethurst, A Blanchard, ... FEBS Open Bio 3, 156-160, 2013 | 40 | 2013 |
| Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist T Benned-Jensen, MM Rosenkilde Molecular pharmacology 74 (4), 1008-1021, 2008 | 38 | 2008 |
| Biased action of the CXCR4-targeting drug plerixafor is essential for its superior hematopoietic stem cell mobilization AS Jørgensen, V Daugvilaite, K De Filippo, C Berg, M Mavri, ... Communications biology 4 (1), 569, 2021 | 23 | 2021 |
| Signaling via G proteins mediates tumorigenic effects of GPR87 KN Arfelt, S Fares, AH Sparre-Ulrich, GM Hjortø, LS Gasbjerg, ... Cellular Signalling 30, 9-18, 2017 | 23 | 2017 |
| EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia–like B-cell malignancies K Niss Arfelt, L Barington, T Benned-Jensen, V Kubale, AL Kovalchuk, ... Blood, The Journal of the American Society of Hematology 129 (7), 866-878, 2017 | 19 | 2017 |
| Conformational constraining of inactive and active states of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V MM Rosenkilde, R David, I Oerlecke, T Benned-Jensen, U Geumann, ... Molecular pharmacology 70 (6), 1892-1901, 2006 | 17 | 2006 |
| EBI2, GPR18, and GPR17-three structurally related but biologically distinct 7TM receptors K Norregaard, T Benned-Jensen, M Marie Rosenkilde Current topics in medicinal chemistry 11 (6), 618-628, 2011 | 15 | 2011 |
| The role of transmembrane segment II in 7TM receptor activation T Benned-Jensen, MM Rosenkilde Current Molecular Pharmacology 2 (2), 140-148, 2009 | 14 | 2009 |
| Biased agonism and allosteric modulation of G protein‐coupled receptor 183–a 7TM receptor also known as Epstein–Barr virus‐induced gene 2 V Daugvilaite, CM Madsen, M Lückmann, CC Echeverria, AW Sailer, ... British journal of pharmacology 174 (13), 2031-2042, 2017 | 13 | 2017 |
| In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic … M Grupe, BH Bentzen, T Benned-Jensen, V Nielsen, K Frederiksen, ... European Journal of Pharmacology 887, 173440, 2020 | 12 | 2020 |
| Lü ttichau HR, Larsen JK, Christensen JP, and Schwartz TW (2006) Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity MM Rosenkilde, T Benned-Jensen, H Andersen, PJ Holst, TN Kledal J Biol Chem 281, 13199-13208, 0 | 5 | |
