|Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies|
BD Lehmann, JA Bauer, X Chen, ME Sanders, AB Chakravarthy, Y Shyr, ...
The Journal of clinical investigation 121 (7), 2750, 2011
|Random forests for genomic data analysis|
X Chen, H Ishwaran
|Refinement of triple-negative breast cancer molecular subtypes: implications for neoadjuvant chemotherapy selection|
BD Lehmann, B Jovanović, X Chen, MV Estrada, KN Johnson, Y Shyr, ...
PloS one 11 (6), 2016
|Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer|
CM Lovly, NT McDonald, H Chen, S Ortiz-Cuaran, LC Heukamp, Y Yan, ...
Nature medicine 20 (9), 1027, 2014
|PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors|
BD Lehmann, JA Bauer, JM Schafer, CS Pendleton, L Tang, KC Johnson, ...
Breast Cancer Research 16 (4), 406, 2014
|Gene set analysis of genome-wide association studies: methodological issues and perspectives|
L Wang, P Jia, RD Wolfinger, X Chen, Z Zhao
Genomics 98 (1), 1-8, 2011
|TNBCtype: A Subtyping Tool for Triple-Negative Breast Cancer|
X Chen, J Li, WH Gray, BD Lehmann, JA Bauer, Y Shyr, JA Pietenpol
Cancer Informatics 11, 147, 2012
|Smad4-Mediated Signaling Inhibits Intestinal Neoplasia by Inhibiting Expression of β-Catenin|
TJ Freeman, JJ Smith, X Chen, MK Washington, JT Roland, AL Means, ...
|Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas|
KT Nam, HJ Lee, JJ Smith, LA Lapierre, VP Kamath, X Chen, BJ Aronow, ...
The Journal of clinical investigation 120 (3), 840, 2010
|Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells|
AB Singh, A Sharma, JJ Smith, M Krishnan, X Chen, S Eschrich, ...
Gastroenterology 141 (6), 2140-2153, 2011
|Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer|
KD Yu, R Zhu, M Zhan, AA Rodriguez, W Yang, S Wong, A Makris, ...
Clinical cancer research 19 (10), 2723-2733, 2013
|Characteristics of lung cancers harboring NRAS mutations|
K Ohashi, LV Sequist, ME Arcila, CM Lovly, X Chen, CM Rudin, T Moran, ...
Clinical Cancer Research 19 (9), 2584-2591, 2013
|Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation|
P Dhawan, R Ahmad, R Chaturvedi, JJ Smith, R Midha, MK Mittal, ...
Oncogene 30 (29), 3234-3247, 2011
|Random survival forests for high‐dimensional data|
H Ishwaran, UB Kogalur, X Chen, AJ Minn
Statistical Analysis and Data Mining 4 (1), 115-132, 2011
|Predicting normal glenoid version from the pathologic scapula: a comparison of 4 methods in 2-and 3-dimensional models|
A Ganapathi, JA McCarron, X Chen, JP Iannotti
Journal of shoulder and elbow surgery 20 (2), 234-244, 2011
|Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma|
CW Barrett, W Ning, X Chen, JJ Smith, MK Washington, KE Hill, ...
Cancer research 73 (3), 1245-1255, 2013
|HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability|
M Krishnan, AB Singh, JJ Smith, A Sharma, X Chen, S Eschrich, ...
Oncogene 29 (2), 305-312, 2009
|Signal transducer and activator of transcription 3, mediated remodeling of the tumor microenvironment results in enhanced tumor drug delivery in a mouse model of pancreatic cancer|
NS Nagathihalli, JA Castellanos, C Shi, Y Beesetty, ML Reyzer, R Caprioli, ...
Gastroenterology 149 (7), 1932-1943. e9, 2015
|Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes|
X Chen, L Wang, JD Smith, B Zhang
Bioinformatics 24 (21), 2474-2481, 2008
|Identification of disease‐associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease|
Z Lin, JP Hegarty, JA Cappel, W Yu, X Chen, P Faber, Y Wang, AA Kelly, ...
Clinical genetics 80 (1), 59-67, 2011