Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ... Nature genetics 50 (4), 524-537, 2018 | 1346 | 2018 |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, ... Nature communications 7 (1), 1-19, 2016 | 502 | 2016 |
Stroke genetics informs drug discovery and risk prediction across ancestries A Mishra, R Malik, T Hachiya, T Jürgenson, S Namba, DC Posner, ... Nature 611 (7934), 115-123, 2022 | 248 | 2022 |
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes MCY Ng, D Shriner, BH Chen, J Li, WM Chen, X Guo, J Liu, SJ Bielinski, ... PLoS genetics 10 (8), e1004517, 2014 | 246 | 2014 |
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations N Franceschini, E Fox, Z Zhang, TL Edwards, MA Nalls, YJ Sung, ... The American Journal of Human Genetics 93 (3), 545-554, 2013 | 237 | 2013 |
Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study NSG Network, SL Pulit, PF McArdle, Q Wong, R Malik, K Gwinn, ... The Lancet Neurology 15 (2), 174-184, 2016 | 175 | 2016 |
Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy MM Sale, SG Smith, JC Mychaleckyj, KL Keene, CD Langefeld, TS Leak, ... Diabetes 56 (10), 2638-2642, 2007 | 143 | 2007 |
Variants in intron 13 of the ELMO1 gene are associated with diabetic nephropathy in African Americans TS Leak, PS Perlegas, SG Smith, KL Keene, PJ Hicks, CD Langefeld, ... Annals of human genetics 73 (2), 152-159, 2009 | 130 | 2009 |
Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with … SR Williams, Q Yang, F Chen, X Liu, KL Keene, P Jacques, WM Chen, ... PLoS genetics 10 (3), e1004214, 2014 | 79 | 2014 |
Meta-analysis of genome-wide association studies identifies genetic risk factors for stroke in African Americans CL Carty, KL Keene, YC Cheng, JF Meschia, WM Chen, M Nalls, JC Bis, ... Stroke 46 (8), 2063-2068, 2015 | 78 | 2015 |
Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2 J Huang, JE Huffman, M Yamakuchi, S Trompet, FW Asselbergs, ... Arteriosclerosis, thrombosis, and vascular biology 34 (5), 1093-1101, 2014 | 51 | 2014 |
Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2 J Huang, JE Huffman, M Yamakuchi, S Trompet, FW Asselbergs, ... Arteriosclerosis, thrombosis, and vascular biology 34 (5), 1093-1101, 2014 | 51 | 2014 |
The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS … MM Sale, FC Hsu, ND Palmer, CJ Gordon, KL Keene, HM Borgerink, ... BMC Endocrine Disorders 7 (1), 1-10, 2007 | 50 | 2007 |
Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population TS Leak, KL Keene, CD Langefeld, CJ Gallagher, JC Mychaleckyj, ... Molecular genetics and metabolism 92 (1-2), 145-150, 2007 | 45 | 2007 |
Investigation of the estrogen receptor-α gene with type 2 diabetes and/or nephropathy in African-American and European-American populations CJ Gallagher, KL Keene, JC Mychaleckyj, CD Langefeld, JN Hirschhorn, ... Diabetes 56 (3), 675-684, 2007 | 44 | 2007 |
Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke SR Williams, FC Hsu, KL Keene, WM Chen, S Nelson, AM Southerland, ... Neurology 86 (4), 351-359, 2016 | 42 | 2016 |
Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy KL Keene, JC Mychaleckyj, SG Smith, TS Leak, PS Perlegas, ... Diabetes 57 (4), 1057-1062, 2008 | 40 | 2008 |
Genetic associations with plasma B12, B6, and folate levels in an ischemic stroke population from the Vitamin Intervention for Stroke Prevention (VISP) trial KL Keene, WM Chen, F Chen, SR Williams, SD Elkhatib, FC Hsu, ... Frontiers in public health 2, 112, 2014 | 39 | 2014 |
Are myocardial infarction–associated single-nucleotide polymorphisms associated with ischemic stroke? YC Cheng, CD Anderson, S Bione, K Keene, JM Maguire, M Nalls, ... Stroke 43 (4), 980-986, 2012 | 38 | 2012 |
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke KL Keene, HI Hyacinth, JC Bis, SJ Kittner, BD Mitchell, YC Cheng, G Pare, ... Stroke 51 (8), 2454-2463, 2020 | 37 | 2020 |