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Basavarajappa D Halesha
Basavarajappa D Halesha
Scientist , Exelixis
Verificeret mail på exelixis.com
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Citeret af
År
Natural product inhibitors of ocular angiogenesis
RS Sulaiman, HD Basavarajappa, TW Corson
Experimental eye research 129, 161-171, 2014
992014
Aminopyrazinamides: Novel and Specific GyrB Inhibitors that Kill Replicating and Nonreplicating Mycobacterium tuberculosis
PS Shirude, P Madhavapeddi, JA Tucker, K Murugan, V Patil, ...
ACS chemical biology 8 (3), 519-523, 2013
902013
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA gyrase B
MG Kale, A Raichurkar, SH P, D Waterson, D McKinney, MR Manjunatha, ...
Journal of medicinal chemistry 56 (21), 8834-8848, 2013
662013
Synthesis and biological evaluation of novel homoisoflavonoids for retinal neovascularization
HD Basavarajappa, B Lee, H Lee, RS Sulaiman, H An, C Magaña, ...
Journal of Medicinal Chemistry 58 (12), 5015-5027, 2015
572015
The first synthesis of the antiangiogenic homoisoflavanone, cremastranone
B Lee, HD Basavarajappa, RS Sulaiman, X Fei, SY Seo, TW Corson
Organic & biomolecular chemistry 12 (39), 7673-7677, 2014
532014
Ferrochelatase is a therapeutic target for ocular neovascularization
HD Basavarajappa, RS Sulaiman, X Qi, T Shetty, S Sheik Pran Babu, ...
EMBO molecular medicine 9 (6), 786-801, 2017
452017
Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer
BL Thériault, HD Basavarajappa, H Lim, S Pajovic, BL Gallie, TW Corson
PLoS One 9 (3), e91540, 2014
442014
Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy
RR Kale, MG Kale, D Waterson, A Raichurkar, SP Hameed, ...
Bioorganic & Medicinal Chemistry Letters 24 (3), 870-879, 2014
442014
Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth
HD Basavarajappa, B Lee, X Fei, D Lim, B Callaghan, JA Mund, J Case, ...
PLoS One 9 (4), e95694, 2014
322014
Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids
B Lee, W Sun, H Lee, H Basavarajappa, RS Sulaiman, K Sishtla, X Fei, ...
Bioorganic & medicinal chemistry letters 26 (17), 4277-4281, 2016
222016
KIF14 as an oncogene in retinoblastoma: a target for novel therapeutics?
HD Basavarajappa, TW Corson
Future medicinal chemistry 4 (17), 2149-2152, 2012
222012
The Antiangiogenic Activity of Naturally Occurring and Synthetic Homoisoflavonoids from the Hyacinthaceae (sensu APGII)
S Schwikkard, H Whitmore, K Sishtla, RS Sulaiman, T Shetty, ...
Journal of natural products 82 (5), 1227-1239, 2019
202019
MeONH2· HCl-Mediated α-Methylenation/Conjugate Addition of α-Sulfonyl o-Hydroxyacetophenones with Methyl Sulfoxides: Route to 3-Sulfonylchroman-4-ones
MY Chang, KT Chen
Synthesis 53 (01), 135-145, 2021
92021
Assays, surrogates, and alternative technologies for a TB lead identification program targeting DNA gyrase ATPase
V Humnabadkar, P Madhavapeddi, H Basavarajappa, MG Sheikh, ...
Journal of Biomolecular Screening 20 (2), 265-274, 2015
62015
One-Pot Access to 2-Aryl-3-(Arylmethyl) Chromones
MY Chang, KT Chen, YL Tsai, HY Chen
Synthesis 52 (06), 861-872, 2020
52020
The adaptor protein NumbL is involved in the control of glucolipotoxicity-induced pancreatic beta cell apoptosis
HD Basavarajappa, JM Irimia, BM Bauer, PT Fueger
International Journal of Molecular Sciences 24 (4), 3308, 2023
22023
Griseofulvin inhibits choroidal neovascularization
TW Corson, RS Sulaiman, S Alkhairy, K Gupta, HD Basavarajappa
Investigative Ophthalmology & Visual Science 57 (12), 2122-2122, 2016
22016
IDENTIFICATION AND CHARACTERIZATION OF A NOVEL SYNTHETIC HOMOISOFLAVONOID AS AN INHIBITOR OF RETINAL ANGIOGENESIS.
HD Basavarajappa, B Lee, J Quigley, R Sulaiman, G Rajashekhar, ...
Investigative ophthalmology & visual science 55 (13), 1266-1266, 2014
22014
Glucolipotoxicity-induced Mig6 desensitizes EGFR signaling and promotes pancreatic beta cell death
YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger
bioRxiv, 2020.11. 24.380279, 2020
12020
Inhibition of ferrochelatase as an antiangiogenic therapy
T Corson, H Basavarajappa
US Patent 10,752,901, 2020
12020
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Artikler 1–20