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Johannes Loffing
Johannes Loffing
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Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na+ channel cell surface expression
C Debonneville, SY Flores, E Kamynina, PJ Plant, C Tauxe, MA Thomas, ...
The EMBO journal, 2001
8232001
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family
L Mastroberardino, B Spindler, R Pfeiffer, PJ Skelly, J Loffing, ...
Nature 395 (6699), 288-291, 1998
6271998
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia
T Nijenhuis, V Vallon, AWCM van der Kemp, J Loffing, JGJ Hoenderop, ...
The Journal of clinical investigation 115 (6), 1651-1658, 2005
5342005
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK
J Loffing, M Zecevic, E Féraille, B Kaissling, C Asher, BC Rossier, ...
American Journal of Physiology-Renal Physiology 280 (4), F675-F682, 2001
4572001
Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome
H Abriel, J Loffing, JF Rebhun, JH Pratt, L Schild, JD Horisberger, D Rotin, ...
The Journal of clinical investigation 103 (5), 667-673, 1999
4491999
Impaired renal Na+ retention in the sgk1-knockout mouse
P Wulff, V Vallon, DY Huang, H Völkl, F Yu, K Richter, M Jansen, ...
The Journal of clinical investigation 110 (9), 1263-1268, 2002
4452002
Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb
M Amemiya, J Loffing, M Lotscher, B Kaissling, RJ Alpern, OW Moe
Kidney international 48 (4), 1206-1215, 1995
4211995
Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression
M Trudu, S Janas, C Lanzani, H Debaix, C Schaeffer, M Ikehata, L Citterio, ...
Nature medicine 19 (12), 1655-1660, 2013
3492013
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron
J Loffing, D Loffing-Cueni, V Valderrabano, L Klausli, SC Hebert, ...
American Journal of Physiology-Renal Physiology 281 (6), F1021-F1027, 2001
3462001
Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice
MV Sorensen, S Grossmann, M Roesinger, N Gresko, AP Todkar, ...
Kidney international 83 (5), 811-824, 2013
3262013
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression
J Cheng, BD Moyer, M Milewski, J Loffing, M Ikeda, JE Mickle, GR Cutting, ...
Journal of Biological Chemistry 277 (5), 3520-3529, 2002
2842002
Differential subcellular localization of ENaC subunits in mouse kidney in response to high-and low-Na diets
J Loffing, L Pietri, F Aregger, M Bloch-Faure, U Ziegler, P Meneton, ...
American Journal of Physiology-Renal Physiology 279 (2), F252-F258, 2000
2672000
Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line
HP Gaeggeler, E Gonzalez-Rodriguez, NF Jaeger, D Loffing-Cueni, ...
Journal of the American Society of Nephrology 16 (4), 878-891, 2005
2452005
Altered renal distal tubule structure and renal Na+ and Ca2+ handling in a mouse model for Gitelman’s syndrome
J Loffing, V Vallon, D Loffing-Cueni, F Aregger, K Richter, L Pietri, ...
Journal of the American Society of Nephrology 15 (9), 2276-2288, 2004
2402004
Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule
P Meneton, J Loffing, DG Warnock
American Journal of Physiology-Renal Physiology 287 (4), F593-F601, 2004
2332004
Collecting duct–specific gene inactivation of αENaC in the mouse kidney does not impair sodium and potassium balance
I Rubera, J Loffing, LG Palmer, G Frindt, N Fowler-Jaeger, D Sauter, ...
The Journal of clinical investigation 112 (4), 554-565, 2003
2282003
Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC)
J Loffing, C Korbmacher
Pflügers Archiv-European Journal of Physiology 458, 111-135, 2009
1942009
Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human
J Loffing, B Kaissling
American Journal of Physiology-Renal Physiology 284 (4), F628-F643, 2003
1872003
Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in Madin-Darby canine …
BD Moyer, J Loffing, EM Schwiebert, D Loffing-Cueni, PA Halpin, ...
Journal of Biological Chemistry 273 (34), 21759-21768, 1998
1831998
Thiazide treatment of rats provokes apoptosis in distal tubule cells
J Loffing, D Loffing-Cueni, I Hegyi, MR Kaplan, SC Hebert, M Le Hir, ...
Kidney international 50 (4), 1180-1190, 1996
1801996
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