TJ Ley
TJ Ley
Professor of Medicine and Genetics, Washington University School of Medicine
Verified email at wustl.edu - Homepage
Title
Cited by
Cited by
Year
Mutational landscape and significance across 12 major cancer types
C Kandoth, MD McLellan, F Vandin, K Ye, B Niu, C Lu, M Xie, Q Zhang, ...
Nature 502 (7471), 333-339, 2013
31212013
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research Network
New England Journal of Medicine 368 (22), 2059-2074, 2013
28102013
Recurring mutations found by sequencing an acute myeloid leukemia genome
ER Mardis, L Ding, DJ Dooling, DE Larson, MD McLellan, K Chen, ...
New England Journal of Medicine 361 (11), 1058-1066, 2009
22062009
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ...
Nature 481 (7382), 506-510, 2012
19072012
DNMT3A Mutations in Acute Myeloid Leukemia
TJ Ley, L Ding, MJ Walter, MD McLellan, T Lamprecht, DE Larson, ...
New England Journal of Medicine 363 (25), 2424-2433, 2010
18712010
International network of cancer genome projects
International Cancer Genome Consortium
Nature 464 (7291), 993, 2010
17112010
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ...
Nature 481 (7380), 157-163, 2012
13522012
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
TJ Ley, ER Mardis, L Ding, B Fulton, MD McLellan, K Chen, D Dooling, ...
Nature 456 (7218), 66-72, 2008
13382008
BreakDancer: an algorithm for high-resolution mapping of genomic structural variation
K Chen, JW Wallis, MD McLellan, DE Larson, JM Kalicki, CS Pohl, ...
Nature methods 6 (9), 677-681, 2009
13192009
The origin and evolution of mutations in acute myeloid leukemia
JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ...
Cell 150 (2), 264-278, 2012
13092012
Lymphocyte-mediated cytotoxicity
JH Russell, TJ Ley
Annual review of immunology 20 (1), 323-370, 2002
12612002
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
WJ Grossman, JW Verbsky, W Barchet, M Colonna, JP Atkinson, TJ Ley
Immunity 21 (4), 589-601, 2004
11992004
Genome remodelling in a basal-like breast cancer metastasis and xenograft
LI Ding, MJ Ellis, S Li, DE Larson, K Chen, JW Wallis, CC Harris, ...
Nature 464 (7291), 999-1005, 2010
11902010
Age-related mutations associated with clonal hematopoietic expansion and malignancies
M Xie, C Lu, J Wang, MD McLellan, KJ Johnson, MC Wendl, ...
Nature medicine 20 (12), 1472-1478, 2014
11552014
Whole-genome analysis informs breast cancer response to aromatase inhibition
MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ...
Nature 486 (7403), 353-360, 2012
9642012
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
JW Heusel, RL Wesselschmidt, S Shresta, JH Russell, TJ Ley
Cell 76 (6), 977-987, 1994
9601994
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance
X Cao, SF Cai, TA Fehniger, J Song, LI Collins, DR Piwnica-Worms, ...
Immunity 27 (4), 635-646, 2007
8652007
Clonal architecture of secondary acute myeloid leukemia
MJ Walter, D Shen, L Ding, J Shao, DC Koboldt, K Chen, DE Larson, ...
New England Journal of Medicine 366 (12), 1090-1098, 2012
7742012
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
A Belaaouaj, R McCarthy, M Baumann, Z Gao, TJ Ley, SN Abraham, ...
Nature medicine 4 (5), 615-618, 1998
7041998
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
WJ Grossman, JW Verbsky, BL Tollefsen, C Kemper, JP Atkinson, TJ Ley
Blood 104 (9), 2840-2848, 2004
5952004
The system can't perform the operation now. Try again later.
Articles 1–20