Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors J Boshuizen, LA Koopman, O Krijgsman, A Shahrabi, EG van den Heuvel, ... Nature medicine 24 (2), 203-212, 2018 | 206 | 2018 |
Augmenting immunotherapy impact by lowering tumor TNF cytotoxicity threshold DW Vredevoogd, T Kuilman, MA Ligtenberg, J Boshuizen, KE Stecker, ... Cell 178 (3), 585-599. e15, 2019 | 183 | 2019 |
A committed tissue-resident memory T cell precursor within the circulating CD8+ effector T cell pool L Kok, FE Dijkgraaf, J Urbanus, K Bresser, DW Vredevoogd, RF Cardoso, ... Journal of Experimental Medicine 217 (10), 2020 | 86 | 2020 |
Reversal of pre-existing NGFR-driven tumor and immune therapy resistance J Boshuizen, DW Vredevoogd, O Krijgsman, MA Ligtenberg, ... Nature communications 11 (1), 3946, 2020 | 78 | 2020 |
Tissue patrol by resident memory CD8+ T cells in human skin FE Dijkgraaf, TR Matos, M Hoogenboezem, M Toebes, DW Vredevoogd, ... Nature immunology 20 (6), 756-764, 2019 | 78 | 2019 |
In vitro-induced human IL-10+ B cells do not show a subset-defining marker signature and plastically co-express IL-10 with pro-inflammatory cytokines LC Lighaam, PPA Unger, DW Vredevoogd, D Verhoeven, E Vermeulen, ... Frontiers in immunology 9, 393103, 2018 | 54 | 2018 |
Cooperative targeting of immunotherapy-resistant melanoma and lung cancer by an AXL-targeting antibody–drug conjugate and immune checkpoint blockade J Boshuizen, N Pencheva, O Krijgsman, DDE Altimari, PG Castro, ... Cancer research 81 (7), 1775-1787, 2021 | 32 | 2021 |
A genome‐wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS‐mutant melanoma A Nagler, DW Vredevoogd, M Alon, PF Cheng, S Trabish, S Kalaora, ... Pigment cell & melanoma research 33 (2), 334-344, 2020 | 29 | 2020 |
Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling G Apriamashvili, DW Vredevoogd, O Krijgsman, OB Bleijerveld, ... Nature communications 13 (1), 1923, 2022 | 27 | 2022 |
RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells Z Zhang, X Kong, MA Ligtenberg, SE Van Hal-van Veen, NL Visser, ... Cell Reports Medicine 3 (6), 2022 | 23 | 2022 |
Augmenting immunotherapy impact by lowering tumor TNF cytotoxicity threshold DW Vredevoogd, T Kuilman, MA Ligtenberg, J Boshuizen, KE Stecker, ... Cell 180 (2), 404-405, 2020 | 20 | 2020 |
The (re) discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens DW Vredevoogd, G Apriamashvili, DS Peeper Immuno-Oncology and Technology 11, 100043, 2021 | 9 | 2021 |
An adverse tumor-protective effect of IDO1 inhibition JCN Kenski, X Huang, DW Vredevoogd, B de Bruijn, JJH Traets, ... Cell Reports Medicine 4 (2), 2023 | 7 | 2023 |
TSC2 regulates tumor susceptibility to TRAIL‐mediated T‐cell killing by orchestrating mTOR signaling CP Lin, JJH Traets, DW Vredevoogd, NL Visser, DS Peeper The EMBO journal 42 (5), e111614, 2023 | 4 | 2023 |
Loss of ubiquitin ligase STUB1 amplifies IFNγ-R1/JAK1 signaling and sensitizes tumors to IFNγ G Apriamashvili, DW Vredevoogd, O Krijgsman, OB Bleijerveld, ... bioRxiv, 2020.07. 07.191650, 2020 | 4 | 2020 |
Enabling oncogenes DW Vredevoogd, DS Peeper Science 373 (6559), 1088-1089, 2021 | 3 | 2021 |
Labeling and tracking of immune cells in ex vivo human skin FE Dijkgraaf, M Toebes, M Hoogenboezem, M Mertz, DW Vredevoogd, ... Nature protocols 16 (2), 791-811, 2021 | 3 | 2021 |
Predictive immune-checkpoint blockade classifiers identify tumors responding to inhibition of PD-1 and/or CTLA-4 O Krijgsman, K Kemper, J Boshuizen, DW Vredevoogd, EA Rozeman, ... Clinical Cancer Research 27 (19), 5389-5400, 2021 | 2 | 2021 |
Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness CP Lin, PL Levy, A Alflen, G Apriamashvili, MA Ligtenberg, ... Cancer Cell 42 (4), 623-645. e10, 2024 | 1 | 2024 |
Author Correction: Tissue patrol by resident memory CD8+ T cells in human skin FE Dijkgraaf, TR Matos, M Hoogenboezem, M Toebes, DW Vredevoogd, ... Nature immunology 21 (6), 696-696, 2020 | 1 | 2020 |