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Lauren Young
Lauren Young
Senior Scientist - Computational Sciences, Beam Therapeutics
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Cited by
Cited by
Year
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
CE Elks, JRB Perry, P Sulem, DI Chasman, N Franceschini, C He, ...
Nature genetics 42 (12), 1077-1085, 2010
6032010
Meta-analysis of genome-wide association studies in> 80 000 subjects identifies multiple loci for C-reactive protein levels
A Dehghan, J Dupuis, M Barbalic, JC Bis, G Eiriksdottir, C Lu, N Pellikka, ...
Circulation 123 (7), 731-738, 2011
5812011
Directed evolution of adenine base editors with increased activity and therapeutic application
NM Gaudelli, DK Lam, HA Rees, NM Solá-Esteves, LA Barrera, DA Born, ...
Nature biotechnology 38 (7), 892-900, 2020
4092020
The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum
DE Neafsey, K Galinsky, RHY Jiang, L Young, SM Sykes, S Saif, S Gujja, ...
Nature genetics 44 (9), 1046-1050, 2012
2752012
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
J He, O Abdel-Wahab, MK Nahas, K Wang, RK Rampal, AM Intlekofer, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3004-3014, 2016
2742016
Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification
B Bulik-Sullivan, J Busby, CD Palmer, MJ Davis, T Murphy, A Clark, ...
Nature biotechnology 37 (1), 55-63, 2019
2522019
Analytical validation of a hybrid capture–based next-generation sequencing clinical assay for genomic profiling of cell-free circulating tumor DNA
TA Clark, JH Chung, M Kennedy, JD Hughes, N Chennagiri, DS Lieber, ...
The Journal of Molecular Diagnostics 20 (5), 686-702, 2018
2092018
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Y Yu, TC Leete, DA Born, L Young, LA Barrera, SJ Lee, HA Rees, ...
Nature Communications 11 (1), 2052, 2020
1612020
Emergence of preexisting MET Y1230C mutation as a resistance mechanism to crizotinib in NSCLC with MET exon 14 skipping
SHI Ou, L Young, AB Schrock, A Johnson, SJ Klempner, VW Zhu, ...
Journal of Thoracic Oncology 12 (1), 137-140, 2017
1212017
Identification of Recurrent FGFR3–TACC3 Fusion Oncogenes from Lung Adenocarcinoma
M Capelletti, ME Dodge, D Ercan, PS Hammerman, SI Park, J Kim, ...
Clinical cancer research 20 (24), 6551-6558, 2014
1102014
Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer
JH Chung, D Pavlick, R Hartmaier, AB Schrock, L Young, B Forcier, P Ye, ...
Annals of Oncology 28 (11), 2866-2873, 2017
762017
Individualized molecular analyses guide efforts (IMAGE): a prospective study of molecular profiling of tissue and blood in metastatic triple-negative breast cancer
HA Parsons, JA Beaver, A Cimino-Mathews, SM Ali, J Axilbund, D Chu, ...
Clinical Cancer Research 23 (2), 379-386, 2017
702017
Hybrid capture–based genomic profiling of circulating tumor DNA from patients with advanced cancers of the gastrointestinal tract or anus
AB Schrock, D Pavlick, SJ Klempner, JH Chung, B Forcier, A Welsh, ...
Clinical Cancer Research 24 (8), 1881-1890, 2018
642018
Dual occurrence of ALK G1202R solvent front mutation and small cell lung cancer transformation as resistance mechanisms to second generation ALK inhibitors without prior …
SHI Ou, TK Lee, L Young, MY Fernandez-Rocha, D Pavlick, AB Schrock, ...
Lung Cancer 106, 110-114, 2017
642017
Failure to validate association between 12p13 variants and ischemic stroke.
International Stroke Genetics Consortium
N Engl J Med 362 (16), 1547-1550, 2010
55*2010
Cytosine base editing enables quadruple-edited allogeneic CART cells for T-ALL
C Diorio, R Murray, M Naniong, L Barrera, A Camblin, J Chukinas, ...
Blood, The Journal of the American Society of Hematology 140 (6), 619-629, 2022
482022
A Case of Metastatic Atypical Neuroendocrine Tumor with ALK Translocation and Diffuse Brain Metastases
VE Wang, L Young, S Ali, VA Miller, A Urisman, J Wolfe, TG Bivona, ...
The oncologist 22 (7), 768-773, 2017
382017
Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma
G de Velasco, SA Wankowicz, R Madison, SM Ali, C Norton, A Duquette, ...
British journal of cancer 118 (9), 1238-1242, 2018
372018
Improved cytosine base editors generated from TadA variants
DK Lam, PR Feliciano, A Arif, T Bohnuud, TP Fernandez, JM Gehrke, ...
Nature Biotechnology 41 (5), 686-697, 2023
362023
Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC
ME Goldberg, M Montesion, L Young, J Suh, J Greenbowe, M Kennedy, ...
PLoS One 13 (11), e0208097, 2018
232018
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