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Ted W. Simon
Ted W. Simon
Ted Simon LLC
Verificeret mail på tedsimon-toxicology.com
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Antibody engineering for the analysis of affinity maturation of an anti‐hapten response.
D Allen, T Simon, F Sablitzky, K Rajewsky, A Cumano
The EMBO journal 7 (7), 1995-2001, 1988
3431988
In vitro to in vivo extrapolation for high throughput prioritization and decision making
SM Bell, X Chang, JF Wambaugh, DG Allen, M Bartels, KLR Brouwer, ...
Toxicology in vitro 47, 213-227, 2018
2002018
Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures
T Simon, JK Britt, RC James
Regulatory Toxicology and Pharmacology 48 (2), 148-170, 2007
1212007
Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes
G Patlewicz, TW Simon, JC Rowlands, RA Budinsky, RA Becker
Regulatory Toxicology and Pharmacology 71 (3), 463-477, 2015
1132015
Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study
RA Budinsky, D Schrenk, T Simon, M Van den Berg, JF Reichard, ...
Critical reviews in toxicology 44 (1), 83-119, 2014
842014
The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events
TW Simon, SS Simons Jr, RJ Preston, AR Boobis, SM Cohen, NG Doerrer, ...
Critical reviews in toxicology 44 (sup3), 17-43, 2014
652014
Modulatory effects of FMRF-NH2 on outward currents and oscillatory activity in heart interneurons of the medicinal leech
TW Simon, CA Opdyke, RL Calabrese
Journal of Neuroscience 12 (2), 525-537, 1992
621992
Evidence-based toxicology for the 21st century: opportunities and challenges
ML Stephens, M Andersen, RA Becker, K Betts, K Boekelheide, E Carney, ...
ALTEX-Alternatives to animal experimentation 30 (1), 74-103, 2013
562013
An exposure: activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept
RA Becker, KP Friedman, TW Simon, MS Marty, G Patlewicz, ...
Regulatory Toxicology and Pharmacology 71 (3), 398-408, 2015
512015
Light-evoked walking in crayfish: Behavioral and neuronal responses triggered
TW Simon, DH Edwards
J Comp Physiol A 166, 745-755, 1990
501990
The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor
RA Becker, G Patlewicz, TW Simon, JC Rowlands, RA Budinsky
Regulatory Toxicology and Pharmacology 73 (1), 172-190, 2015
492015
Human and Rat Primary Hepatocyte CYP1A1 and 1A2 Induction with 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 2,3,4,7,8 …
RA Budinsky, EL LeCluyse, SS Ferguson, JC Rowlands, T Simon
Toxicological Sciences 118 (1), 224-235, 2010
462010
How well can carcinogenicity be predicted by high throughput “characteristics of carcinogens” mechanistic data?
RA Becker, DA Dreier, MK Manibusan, LAT Cox, TW Simon, JS Bus
Regulatory Toxicology and Pharmacology 90, 185-196, 2017
452017
Use and validation of HT/HC assays to support 21st century toxicity evaluations
G Patlewicz, T Simon, K Goyak, RD Phillips, JC Rowlands, SD Seidel, ...
Regulatory Toxicology and Pharmacology 65 (2), 259-268, 2013
442013
Two-dimensional Monte Carlo simulation and beyond: a comparison of several probabilistic risk assessment methods applied to a superfund site
TW Simon
Human and Ecological Risk Assessment: An International Journal 5 (4), 823-843, 1999
421999
Providing context for phosphatidylethanol as a biomarker of alcohol consumption with a pharmacokinetic model
TW Simon
Regulatory Toxicology and Pharmacology 94, 163-171, 2018
412018
Utilizing threshold of toxicological concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals
G Patlewicz, JF Wambaugh, SP Felter, TW Simon, RA Becker
Computational Toxicology 7, 58-67, 2018
382018
Modulation of high-threshold transmission between heart interneurons of the medicinal leech by FMRF-NH2
TW Simon, J Schmidt, RL Calabrese
Journal of neurophysiology 71 (2), 454-466, 1994
361994
Estimates of Cancer Potency of 2,3,7,8-Tetrachlorodibenzo(p)dioxin Using Linear and Nonlinear Dose-Response Modeling and Toxicokinetics
T Simon, LL Aylward, CR Kirman, JC Rowlands, RA Budinsky
Toxicological sciences 112 (2), 490-506, 2009
352009
Approaches for describing and communicating overall uncertainty in toxicity characterizations: US Environmental Protection Agency's Integrated Risk Information System (IRIS) as …
NB Beck, RA Becker, N Erraguntla, WH Farland, RL Grant, G Gray, ...
Environment international 89, 110-128, 2016
342016
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