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Matthew A. Coelho
Matthew A. Coelho
Wellcome Sanger Institute
Verified email at sanger.ac.uk - Homepage
Title
Cited by
Cited by
Year
Oncogenic RAS signaling promotes tumor immunoresistance by stabilizing PD-L1 mRNA
MA Coelho, S de Carné Trécesson, S Rana, D Zecchin, C Moore, ...
Immunity 47 (6), 1083-1099. e6, 2017
5712017
High-content CRISPR screening
C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ...
Nature Reviews Methods Primers 2 (1), 1-23, 2022
4482022
CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs
MA Coelho, E De Braekeleer, M Firth, M Bista, S Lukasiak, ME Cuomo, ...
Nature communications 11 (1), 4132, 2020
762020
BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
MA Coelho, S Li, LS Pane, M Firth, G Ciotta, JD Wrigley, ME Cuomo, ...
BMC biology 16, 1-11, 2018
592018
An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations
J Boumelha, S de Carné Trécesson, EK Law, P Romero-Clavijo, ...
Cancer research 82 (19), 3435-3448, 2022
412022
Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius
RS Anjum, SM Bray, JK Blackwood, ML Kilkenny, MA Coelho, BM Foster, ...
Nature communications 6 (1), 8163, 2015
392015
Base editing screens map mutations affecting interferon-γ signaling in cancer
MA Coelho, S Cooper, ME Strauss, E Karakoc, S Bhosle, E Goncalves, ...
Cancer Cell 41 (2), 288-303. e6, 2023
382023
Universal toxin-based selection for precise genome engineering in human cells
S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ...
Nature communications 12 (1), 497, 2021
362021
Cancer immune evasion through KRAS and PD-L1 and potential therapeutic interventions
A Watterson, MA Coelho
Cell Communication and Signaling 21 (1), 45, 2023
182023
Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells
G Picco, Y Rao, A Al Saedi, Y Lee, SF Vieira, S Bhosle, K May, ...
Cancer discovery 14 (8), 1457-1475, 2024
72024
scSNV-seq: high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics
SE Cooper, MA Coelho, ME Strauss, AM Gontarczyk, Q Wu, MJ Garnett, ...
Genome Biology 25 (1), 20, 2024
62024
Analyzing the functional effects of DNA variants with gene editing
S Cooper, S Obolenski, AJ Waters, AR Bassett, MA Coelho
Cell Reports Methods, 2024
22024
Base editing screens define the genetic landscape of cancer drug resistance mechanisms
MA Coelho, ME Strauss, A Watterson, S Cooper, S Bhosle, G Illuzzi, ...
Nature Genetics, 1-14, 2024
12024
12 Oral: On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer
G Picco, Y Rao, A Al Saedi, S Vieira, Y Lee, S Walker, S Bhosle, K May, ...
European Journal of Cancer 211, 114541, 2024
2024
DNA Base Editing Strategies for Genome Editing
M Coelho, S Li, BJM Taylor
Genome Editing in Drug Discovery, 193-202, 2022
2022
Mapping drug resistance variants in cancer, one base at a time
MA Coelho, MJ Garnett
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