Oncogenic RAS signaling promotes tumor immunoresistance by stabilizing PD-L1 mRNA MA Coelho, S de Carné Trécesson, S Rana, D Zecchin, C Moore, ... Immunity 47 (6), 1083-1099. e6, 2017 | 571 | 2017 |
High-content CRISPR screening C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ... Nature Reviews Methods Primers 2 (1), 1-23, 2022 | 448 | 2022 |
CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs MA Coelho, E De Braekeleer, M Firth, M Bista, S Lukasiak, ME Cuomo, ... Nature communications 11 (1), 4132, 2020 | 76 | 2020 |
BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B MA Coelho, S Li, LS Pane, M Firth, G Ciotta, JD Wrigley, ME Cuomo, ... BMC biology 16, 1-11, 2018 | 59 | 2018 |
An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations J Boumelha, S de Carné Trécesson, EK Law, P Romero-Clavijo, ... Cancer research 82 (19), 3435-3448, 2022 | 41 | 2022 |
Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius RS Anjum, SM Bray, JK Blackwood, ML Kilkenny, MA Coelho, BM Foster, ... Nature communications 6 (1), 8163, 2015 | 39 | 2015 |
Base editing screens map mutations affecting interferon-γ signaling in cancer MA Coelho, S Cooper, ME Strauss, E Karakoc, S Bhosle, E Goncalves, ... Cancer Cell 41 (2), 288-303. e6, 2023 | 38 | 2023 |
Universal toxin-based selection for precise genome engineering in human cells S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ... Nature communications 12 (1), 497, 2021 | 36 | 2021 |
Cancer immune evasion through KRAS and PD-L1 and potential therapeutic interventions A Watterson, MA Coelho Cell Communication and Signaling 21 (1), 45, 2023 | 18 | 2023 |
Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells G Picco, Y Rao, A Al Saedi, Y Lee, SF Vieira, S Bhosle, K May, ... Cancer discovery 14 (8), 1457-1475, 2024 | 7 | 2024 |
scSNV-seq: high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics SE Cooper, MA Coelho, ME Strauss, AM Gontarczyk, Q Wu, MJ Garnett, ... Genome Biology 25 (1), 20, 2024 | 6 | 2024 |
Analyzing the functional effects of DNA variants with gene editing S Cooper, S Obolenski, AJ Waters, AR Bassett, MA Coelho Cell Reports Methods, 2024 | 2 | 2024 |
Base editing screens define the genetic landscape of cancer drug resistance mechanisms MA Coelho, ME Strauss, A Watterson, S Cooper, S Bhosle, G Illuzzi, ... Nature Genetics, 1-14, 2024 | 1 | 2024 |
12 Oral: On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer G Picco, Y Rao, A Al Saedi, S Vieira, Y Lee, S Walker, S Bhosle, K May, ... European Journal of Cancer 211, 114541, 2024 | | 2024 |
DNA Base Editing Strategies for Genome Editing M Coelho, S Li, BJM Taylor Genome Editing in Drug Discovery, 193-202, 2022 | | 2022 |
Mapping drug resistance variants in cancer, one base at a time MA Coelho, MJ Garnett | | |