Matthew A. Coelho
Matthew A. Coelho
Wellcome Sanger Institute
Verified email at
Cited by
Cited by
Oncogenic RAS signaling promotes tumor immunoresistance by stabilizing PD-L1 mRNA
MA Coelho, S de Carné Trécesson, S Rana, D Zecchin, C Moore, ...
Immunity 47 (6), 1083-1099. e6, 2017
High-content CRISPR screening
C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ...
Nature Reviews Methods Primers 2 (1), 1-23, 2022
CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs
MA Coelho, E De Braekeleer, M Firth, M Bista, S Lukasiak, ME Cuomo, ...
Nature communications 11 (1), 4132, 2020
BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
MA Coelho, S Li, LS Pane, M Firth, G Ciotta, JD Wrigley, ME Cuomo, ...
BMC biology 16, 1-11, 2018
Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius
RS Anjum, SM Bray, JK Blackwood, ML Kilkenny, MA Coelho, BM Foster, ...
Nature communications 6 (1), 8163, 2015
An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations
J Boumelha, S de Carné Trécesson, EK Law, P Romero-Clavijo, ...
Cancer research 82 (19), 3435-3448, 2022
Universal toxin-based selection for precise genome engineering in human cells
S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ...
Nature communications 12 (1), 497, 2021
Base editing screens map mutations affecting interferon-γ signaling in cancer
MA Coelho, S Cooper, ME Strauss, E Karakoc, S Bhosle, E Goncalves, ...
Cancer Cell 41 (2), 288-303. e6, 2023
Cancer immune evasion through KRAS and PD-L1 and potential therapeutic interventions
A Watterson, MA Coelho
Cell Communication and Signaling 21 (1), 45, 2023
scSNV-seq: high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics
SE Cooper, MA Coelho, ME Strauss, AM Gontarczyk, Q Wu, MJ Garnett, ...
Genome Biology 25 (1), 20, 2024
Abstract B020: Novel WRN helicase inhibitors selectively target microsatellite unstable cancer cells
G Picco, Y Rao, A Al Saedi, Y Lee, S Bhosle, C Herranz-Ors, S Walker, ...
Molecular Cancer Therapeutics 23 (6_Supplement), B020-B020, 2024
Analyzing the functional effects of DNA variants with gene editing
S Cooper, S Obolenski, AJ Waters, AR Bassett, MA Coelho
Cell Reports Methods, 2024
Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells.
G Picco, Y Rao, A Al Saedi, Y Lee, SF Vieira, S Bhosle, K May, ...
Cancer Discovery, 2024
DNA Base Editing Strategies for Genome Editing
M Coelho, S Li, BJM Taylor
Genome Editing in Drug Discovery, 193-202, 2022
The system can't perform the operation now. Try again later.
Articles 1–14