An immunoproteomic approach to characterize the CAR interactome and signalosome MC Ramello, I Benzaïd, BM Kuenzi, M Lienlaf-Moreno, WM Kandell, ... Science signaling 12 (568), eaap9777, 2019 | 133 | 2019 |
Synthesis and biological evaluation of naphthoquinone analogs as a novel class of proteasome inhibitors HR Lawrence, A Kazi, Y Luo, R Kendig, Y Ge, S Jain, K Daniel, ... Bioorganic & medicinal chemistry 18 (15), 5576-5592, 2010 | 100 | 2010 |
Virtual screening of integrase inhibitors by large scale binding free energy calculations: the SAMPL4 challenge E Gallicchio, N Deng, P He, L Wickstrom, AL Perryman, DN Santiago, ... Journal of computer-aided molecular design 28, 475-490, 2014 | 66 | 2014 |
Virtual screening with AutoDock Vina and the common pharmacophore engine of a low diversity library of fragments and hits against the three allosteric sites of HIV integrase … AL Perryman, DN Santiago, S Forli, D Santos-Martins, AJ Olson Journal of computer-aided molecular design 28, 429-441, 2014 | 55 | 2014 |
Virtual target screening: validation using kinase inhibitors DN Santiago, Y Pevzner, AA Durand, MP Tran, RR Scheerer, K Daniel, ... Journal of chemical information and modeling 52 (8), 2192-2203, 2012 | 39 | 2012 |
Fighting cancer with mathematics and viruses DN Santiago, JPW Heidbuechel, WM Kandell, R Walker, J Djeu, ... Viruses 9 (9), 239, 2017 | 37 | 2017 |
Facile iterative synthesis of 2, 5-terpyrimidinylenes as nonpeptidic α-helical mimics L Anderson, M Zhou, V Sharma, JM McLaughlin, DN Santiago, ... The Journal of organic chemistry 75 (12), 4288-4291, 2010 | 24 | 2010 |
In silico Characterization of an Atypical MAPK Phosphatase of Plasmodium falciparum as a Suitable Target for Drug Discovery CO Campbell, DN Santiago, WC Guida, R Manetsch, JH Adams Chemical biology & drug design 84 (2), 158-168, 2014 | 12 | 2014 |
Virtual target screening to rapidly identify potential protein targets of natural products in drug discovery Y Pevzner, DN Santiago, JL von Salm, RS Metcalf, KG Daniel, L Calcul, ... AIMS Molecular Science 1 (2), 81-98, 2014 | 4 | 2014 |
Fighting cancer with mathematics and viruses. Viruses 2017; 9 (9): 239 DN Santiago, JPW Heidbuechel, WM Kandell, R Walker, J Djeu, ... Epub 2017/08/24, 0 | 4 | |
Bioactivity improvement via display of the hydrophobic core of HYD1 in a cyclic β‐hairpin‐like scaffold, MTI‐101 P Jain, DB Badger, Y Liang, AW Gebhard, D Santiago, P Murray, ... Peptide Science 113 (3), e24199, 2021 | 2 | 2021 |
Targeting bioactive chemical space with a small natural products library: Expanding diversity and predictability JL von Salm, D Santiago, NG Wilson, L Calcul, DE Kyle, WC Guida, ... Planta Medica 81 (11), CL11, 2015 | 1 | 2015 |
Acylsulfonamides and processes for producing the same R Manetsch, S Kulkarni, ID Iyamu, HG Wang, K Doi, W Guida, D Santiago, ... US Patent App. 13/814,765, 2013 | 1 | 2013 |
Leveraging artificial intelligence to advance immuno-oncology drug development using functional ex-vivo 3D-tumor organoid platforms of fresh patient tissue samples J Kreahling, D Santiago, V Agrawal, M Pabon, S Altiok, M Page JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |
Oncolytic Viruses to Enhance BiTE and CAR Therapy of Solid Tumors JPW Heidbuechel, T Speck, R Veinalde, D Abate-Daga, DN Santiago, ... MOLECULAR THERAPY 26 (5), 9-10, 2018 | | 2018 |
Chimeric antigen receptors interact with multiple endogenous T cell proteins and induce tonic signaling through phosphorylation of endogenous CD3 zeta MC Ramello, I Benzaid, BM Kuenzi, M Lienlaf, WM Kandell, DN Santiago, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 5, 2017 | | 2017 |
Enhancement of CAR-T cell tumor tropism through expression of CXCR2 chemokine receptors I Benzaid, D Santiago, C Ramello, M Pabon, W Kandell, T Boyle, ... JOURNAL FOR IMMUNOTHERAPY OF CANCER 5, 2017 | | 2017 |
Targeting bioactive chemical space with a small natural products library: Expanding diversity and predictability SJL Von, D Santiago, NG Wilson, L Calcul, DE Kyle, WC Guida, BJ Baker PLANTA MEDICA 81 (11), 916-916, 2015 | | 2015 |
Acylsulfonamides and processes for producing the same R Manetsch, SS Kulkarni, ID Iyamu, H WANG, K Doi, WC Guida, ... | | 2012 |
Use and development of computational tools in drug discovery: from small molecules to cyclic peptides DN Santiago University of South Florida, 2012 | | 2012 |