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Andrew Brown
Andrew Brown
Principal investigator, University of Dundee
Verificeret mail på dundee.ac.uk
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Genetic effects on gene expression across human tissues
GTEx Consortium
Nature 550 (7675), 204, 2017
3294*2017
The GTEx Consortium atlas of genetic regulatory effects across human tissues
GTEx Consortium
Science 369 (6509), 1318-1330, 2020
23732020
Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
1127*2021
Common genetic variants influence human subcortical brain structures
DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez, S Desrivières, ...
Nature, 2015
8322015
Identification of common variants associated with human hippocampal and intracranial volumes
JL Stein, SE Medland, AA Vasquez, DP Hibar, RE Senstad, AM Winkler, ...
Nature genetics 44 (5), 552-561, 2012
6962012
Fast and efficient QTL mapper for thousands of molecular phenotypes
H Ongen, A Buil, AA Brown, ET Dermitzakis, O Delaneau
Bioinformatics 32 (10), 1479-1485, 2015
4602015
The impact of sex on gene expression across human tissues
M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ...
Science 369 (6509), 2020
4022020
Gene expression changes with age in skin, adipose tissue, blood and brain
D Glass, A Viñuela, MN Davies, A Ramasamy, L Parts, D Knowles, ...
Genome biology 14 (7), R75, 2013
2932013
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
L Athanasiu, M Mattingsdal, AK Kähler, A Brown, O Gustafsson, I Agartz, ...
Journal of psychiatric research 44 (12), 748-753, 2010
2722010
A complete tool set for molecular QTL discovery and analysis
O Delaneau, H Ongen, AA Brown, A Fort, NI Panousis, ET Dermitzakis
Nature communications 8, 15452, 2017
2692017
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
JNC Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, ...
Nature genetics 48 (2), 189, 2016
2522016
Cell type–specific genetic regulation of gene expression across human tissues
S Kim-Hellmuth, F Aguet, M Oliva, M Muñoz-Aguirre, S Kasela, V Wucher, ...
Science 369 (6509), 2020
2502020
Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins
A Buil, AA Brown, T Lappalainen, A Viñuela, MN Davies, HF Zheng, ...
Nature genetics 47 (1), 88, 2015
2322015
Estimating the causal tissues for complex traits and diseases
H Ongen, AA Brown, O Delaneau, NI Panousis, AC Nica, ET Dermitzakis, ...
Nature genetics 49 (12), 1676, 2017
1872017
Genetic interactions affecting human gene expression identified by variance association mapping
AA Brown, A Buil, A Viñuela, T Lappalainen, HF Zheng, JB Richards, ...
eLife 3, 2014
1372014
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis
DA Hinds, A Buil, D Ziemek, A Martinez-Perez, R Malik, L Folkersen, ...
Human molecular genetics 25 (9), 1867-1874, 2016
1352016
Sex-dependent association of common variants of microcephaly genes with brain structure
LM Rimol, I Agartz, S Djurovic, AA Brown, JC Roddey, AK Kähler, ...
Proceedings of the National Academy of Sciences 107 (1), 384-388, 2010
1352010
Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change
P Mohammadi, SE Castel, AA Brown, T Lappalainen
Genome research 27 (11), 1872-1884, 2017
1322017
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
A Amin Al Olama, T Dadaev, DJ Hazelett, Q Li, D Leongamornlert, ...
Human molecular genetics 24 (19), 5589-5602, 2015
1112015
Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort
A Vinuela, AA Brown, A Buil, PC Tsai, MN Davies, JT Bell, ET Dermitzakis, ...
Human molecular genetics 27 (4), 732-741, 2017
1052017
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Artikler 1–20