|Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex|
YS Jung, JI Park
Experimental & Molecular Medicine 52 (2), 183-191, 2020
|Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function|
SH Lee, SJ Lee, YS Jung, Y Xu, HS Kang, NC Ha, BJ Park
Neoplasia 11 (1), 22-IN6, 2009
|LIG4 mediates Wnt signalling-induced radioresistance|
S Jun, YS Jung, HN Suh, W Wang, MJ Kim, YS Oh, EM Lien, X Shen, ...
Nature communications 7 (1), 10994, 2016
|Role of CK1 in GSK3β-mediated phosphorylation and degradation of snail|
Y Xu, SH Lee, HS Kim, NH Kim, S Piao, SH Park, YS Jung, JI Yook, ...
Oncogene 29 (21), 3124-3133, 2010
|Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype|
SJ Lee, YS Jung, MH Yoon, S Kang, AY Oh, JH Lee, SY Jun, TG Woo, ...
The Journal of clinical investigation 126 (10), 3879-3893, 2016
|PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness|
X Wang, YS Jung, S Jun, S Lee, W Wang, A Schneider, Y Sun Oh, SH Lin, ...
Nature communications 7 (1), 10633, 2016
|Wnt2 complements Wnt/β-catenin signaling in colorectal cancer|
YS Jung, S Jun, SH Lee, A Sharma, JI Park
Oncotarget 6 (35), 37257, 2015
|TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling|
YS Jung, S Jun, MJ Kim, SH Lee, HN Suh, EM Lien, HY Jung, S Lee, ...
Nature cell biology 20 (12), 1421-1433, 2018
|Quiescence exit of tert+ stem cells by Wnt/β-catenin is indispensable for intestinal regeneration|
HN Suh, MJ Kim, YS Jung, EM Lien, S Jun, JI Park
Cell reports 21 (9), 2571-2584, 2017
|Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells|
SH Lee, GN Shen, YS Jung, SJ Lee, JY Chung, HS Kim, Y Xu, Y Choi, ...
Oncogene 29 (32), 4576-4587, 2010
|Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease|
JY Chung, SJ Lee, SH Lee, YS Jung, NC Ha, W Seol, BJ Park
Neurosignals 19 (2), 86-96, 2011
|Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin|
YS Jung, W Wang, S Jun, J Zhang, M Srivastava, MJ Kim, EM Lien, ...
Nature cell biology 20 (11), 1303-1314, 2018
|Elevated TRAF2/6 expression in Parkinson’s disease is caused by the loss of Parkin E3 ligase activity|
JY Chung, HR Park, SJ Lee, SH Lee, JS Kim, YS Jung, SH Hwang, ...
Laboratory investigation 93 (6), 663-676, 2013
|Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1–PUMA pathway|
SH Lee, YS Jung, JY Chung, AY Oh, SJ Lee, DH Choi, SM Jang, KS Jang, ...
Cell death & disease 2 (12), e235-e235, 2011
|p53, secreted by K-Ras–Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker|
SH Lee, SJ Lee, JY Chung, YS Jung, SY Choi, SH Hwang, D Choi, NC Ha, ...
Oncogene 28 (19), 2005-2014, 2009
|Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions|
YS Jung, SJ Lee, MH Yoon, NC Ha, BJ Park
Cell cycle 11 (23), 4462-4473, 2012
|PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis|
MJ Kim, C Cervantes, YS Jung, X Zhang, J Zhang, SH Lee, S Jun, ...
Molecular cell 81 (8), 1698-1714. e6, 2021
|TMEM9‐v‐ATPase activates Wnt/β‐catenin signaling via APC lysosomal degradation for liver regeneration and tumorigenesis|
YS Jung, SA Stratton, SH Lee, MJ Kim, S Jun, J Zhang, B Zheng, ...
Hepatology 73 (2), 776-794, 2021
|Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression|
AY Oh, YS Jung, J Kim, JH Lee, JH Cho, HY Chun, S Park, H Park, S Lim, ...
Cancer Research 76 (16), 4791-4804, 2016
|Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening|
SJ Lee, YS Jung, SH Lee, HY Chung, BJ Park
International journal of oncology 34 (6), 1637-1643, 2009