Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex YS Jung, JI Park Experimental & Molecular Medicine 52 (2), 183-191, 2020 | 307 | 2020 |
Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function SH Lee, SJ Lee, YS Jung, Y Xu, HS Kang, NC Ha, BJ Park Neoplasia 11 (1), 22-IN6, 2009 | 113 | 2009 |
LIG4 mediates Wnt signalling-induced radioresistance S Jun, YS Jung, HN Suh, W Wang, MJ Kim, YS Oh, EM Lien, X Shen, ... Nature communications 7 (1), 10994, 2016 | 95 | 2016 |
Role of CK1 in GSK3β-mediated phosphorylation and degradation of snail Y Xu, SH Lee, HS Kim, NH Kim, S Piao, SH Park, YS Jung, JI Yook, ... Oncogene 29 (21), 3124-3133, 2010 | 87 | 2010 |
Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype SJ Lee, YS Jung, MH Yoon, S Kang, AY Oh, JH Lee, SY Jun, TG Woo, ... The Journal of clinical investigation 126 (10), 3879-3893, 2016 | 84 | 2016 |
PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness X Wang, YS Jung, S Jun, S Lee, W Wang, A Schneider, Y Sun Oh, SH Lin, ... Nature communications 7 (1), 10633, 2016 | 74 | 2016 |
Wnt2 complements Wnt/β-catenin signaling in colorectal cancer YS Jung, S Jun, SH Lee, A Sharma, JI Park Oncotarget 6 (35), 37257, 2015 | 67 | 2015 |
TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling YS Jung, S Jun, MJ Kim, SH Lee, HN Suh, EM Lien, HY Jung, S Lee, ... Nature cell biology 20 (12), 1421-1433, 2018 | 61 | 2018 |
Quiescence exit of tert+ stem cells by Wnt/β-catenin is indispensable for intestinal regeneration HN Suh, MJ Kim, YS Jung, EM Lien, S Jun, JI Park Cell reports 21 (9), 2571-2584, 2017 | 45 | 2017 |
Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells SH Lee, GN Shen, YS Jung, SJ Lee, JY Chung, HS Kim, Y Xu, Y Choi, ... Oncogene 29 (32), 4576-4587, 2010 | 45 | 2010 |
Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease JY Chung, SJ Lee, SH Lee, YS Jung, NC Ha, W Seol, BJ Park Neurosignals 19 (2), 86-96, 2011 | 43 | 2011 |
Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin YS Jung, W Wang, S Jun, J Zhang, M Srivastava, MJ Kim, EM Lien, ... Nature cell biology 20 (11), 1303-1314, 2018 | 42 | 2018 |
Elevated TRAF2/6 expression in Parkinson’s disease is caused by the loss of Parkin E3 ligase activity JY Chung, HR Park, SJ Lee, SH Lee, JS Kim, YS Jung, SH Hwang, ... Laboratory investigation 93 (6), 663-676, 2013 | 39 | 2013 |
Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1–PUMA pathway SH Lee, YS Jung, JY Chung, AY Oh, SJ Lee, DH Choi, SM Jang, KS Jang, ... Cell death & disease 2 (12), e235-e235, 2011 | 37 | 2011 |
p53, secreted by K-Ras–Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker SH Lee, SJ Lee, JY Chung, YS Jung, SY Choi, SH Hwang, D Choi, NC Ha, ... Oncogene 28 (19), 2005-2014, 2009 | 37 | 2009 |
Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions YS Jung, SJ Lee, MH Yoon, NC Ha, BJ Park Cell cycle 11 (23), 4462-4473, 2012 | 36 | 2012 |
PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis MJ Kim, C Cervantes, YS Jung, X Zhang, J Zhang, SH Lee, S Jun, ... Molecular cell 81 (8), 1698-1714. e6, 2021 | 28 | 2021 |
TMEM9‐v‐ATPase activates Wnt/β‐catenin signaling via APC lysosomal degradation for liver regeneration and tumorigenesis YS Jung, SA Stratton, SH Lee, MJ Kim, S Jun, J Zhang, B Zheng, ... Hepatology 73 (2), 776-794, 2021 | 26 | 2021 |
Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression AY Oh, YS Jung, J Kim, JH Lee, JH Cho, HY Chun, S Park, H Park, S Lim, ... Cancer Research 76 (16), 4791-4804, 2016 | 25 | 2016 |
Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening SJ Lee, YS Jung, SH Lee, HY Chung, BJ Park International journal of oncology 34 (6), 1637-1643, 2009 | 23 | 2009 |