| Hypoxia is a major stimulator of osteoclast formation and bone resorption TR Arnett, DC Gibbons, JC Utting, IR Orriss, A Hoebertz, M Rosendaal, ... Journal of cellular physiology 196 (1), 2-8, 2003 | 405 | 2003 |
| Hypoxia inhibits the growth, differentiation and bone-forming capacity of rat osteoblasts JC Utting, SP Robins, A Brandao-Burch, IR Orriss, J Behar, TR Arnett Experimental cell research 312 (10), 1693-1702, 2006 | 355 | 2006 |
| Acidosis Inhibits Bone Formation by Osteoblasts In Vitro by Preventing Mineralization A Brandao-Burch, JC Utting, IR Orriss, TR Arnett Calcified tissue international 77, 167-174, 2005 | 304 | 2005 |
| Extracellular Nucleotides Block Bone Mineralization in Vitro: Evidence for Dual Inhibitory Mechanisms Involving Both P2Y2 Receptors and Pyrophosphate IR Orriss, JC Utting, A Brandao-Burch, K Colston, BR Grubb, G Burnstock, ... Endocrinology 148 (9), 4208-4216, 2007 | 164 | 2007 |
| Inhibition of osteoblast function in vitro by aminobisphosphonates IR Orriss, ML Key, KW Colston, TR Arnett Journal of cellular biochemistry 106 (1), 109-118, 2009 | 161 | 2009 |
| Pyrophosphate: a key inhibitor of mineralisation IR Orriss, TR Arnett, RGG Russell Current opinion in pharmacology 28, 57-68, 2016 | 156 | 2016 |
| Hypoxia stimulates vesicular ATP release from rat osteoblasts IR Orriss, GE Knight, JC Utting, SEB Taylor, G Burnstock, TR Arnett Journal of cellular physiology 220 (1), 155-162, 2009 | 155 | 2009 |
| Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer SR Rao, AE Snaith, D Marino, X Cheng, ST Lwin, IR Orriss, FC Hamdy, ... British journal of cancer 116 (2), 227-236, 2017 | 154 | 2017 |
| Purinergic signalling and bone remodelling IR Orriss, G Burnstock, TR Arnett Current opinion in pharmacology 10 (3), 322-330, 2010 | 150 | 2010 |
| Osteoblast responses to nucleotides increase during differentiation IR Orriss, GE Knight, S Ranasinghe, G Burnstock, TR Arnett Bone 39 (2), 300-309, 2006 | 147 | 2006 |
| Purinergic signalling in the musculoskeletal system G Burnstock, TR Arnett, IR Orriss Purinergic signalling 9, 541-572, 2013 | 136 | 2013 |
| Hypoxia stimulates osteoclast formation from human peripheral blood JC Utting, AM Flanagan, A Brandao‐Burch, IR Orriss, TR Arnett Cell biochemistry and function 28 (5), 374-380, 2010 | 121 | 2010 |
| The P2X7 receptor is an important regulator of extracellular ATP levels A Brandao-Burch, ML Key, JJ Patel, TR Arnett, IR Orriss Frontiers in endocrinology 3, 17734, 2012 | 116 | 2012 |
| Generation of rodent and human osteoblasts SEB Taylor, M Shah, IR Orriss BoneKEy reports 3, 2014 | 109 | 2014 |
| The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors IR Orriss, ML Key, A Brandao-Burch, JJ Patel, G Burnstock, TR Arnett Bone 51 (3), 389-400, 2012 | 106 | 2012 |
| Chronic administration of Glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice M Pereira, J Jeyabalan, CS Jørgensen, M Hopkinson, A Al-Jazzar, ... Bone 81, 459-467, 2015 | 98 | 2015 |
| Metabolic properties of the osteoclast TR Arnett, IR Orriss Bone 115, 25-30, 2018 | 88 | 2018 |
| Rat osteoblast cultures IR Orriss, SEB Taylor, TR Arnett Bone research protocols, 31-41, 2012 | 85 | 2012 |
| Bone phenotypes of P2 receptor knockout mice I Orriss, S Syberg, N Wang, B Robaye, A Gartland, N Jorgensen, T Arnett, ... Front Biosci (Schol Ed) 3 (3), 1038-1046, 2011 | 83 | 2011 |
| Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebral disc (IVD) degeneration treatment T Serra, C Capelli, R Toumpaniari, IR Orriss, JJH Leong, K Dalgarno, ... Biofabrication 8 (3), 035001, 2016 | 76 | 2016 |
