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Franz Oesch
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Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds
F Oesch
Xenobiotica 3 (5), 305-340, 1973
10661973
A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide
F Oesch, DM Jerina, J Daly
Biochimica et Biophysica Acta (BBA)-Enzymology 227 (3), 685-691, 1971
5411971
Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations—many questions, some answers
R Landsiedel, MD Kapp, M Schulz, K Wiench, F Oesch
Mutation Research/Reviews in Mutation Research 681 (2-3), 241-258, 2009
4652009
A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathioneS-transferase GSTM1 and GSTT1 polymorphisms
M Arand, R Mühlbauer, J Hengstler, E Jäger, J Fuchs, L Winkler, F Oesch
Analytical biochemistry 236 (1), 184-186, 1996
4491996
Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma
E Jäger, M Ringhoffer, M Altmannsberger, M Arand, J Karbach, D Jäger, ...
International journal of cancer 71 (2), 142-147, 1997
4101997
Hepatic epoxide hydrase. Structure-activity relations for substrates and inhibitors
F Oesch, N Kaubisch, DM Jerina, JW Daly
Biochemistry 10 (26), 4858-4866, 1971
3941971
Granulocyte‐macrophage‐colony‐stimulating factor enhances immune responses to melanoma‐associated peptides in vivo
E Jäger, M Ringhoffer, HP Dienes, M Arand, J Karbach, D Jäger, ...
International journal of cancer 67 (1), 54-62, 1996
3761996
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
T Efferth, A Benakis, MR Romero, M Tomicic, R Rauh, D Steinbach, ...
Free Radical Biology and Medicine 37 (7), 998-1009, 2004
3722004
Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic‐T‐cell responses: Evidence for immunoselection of antigen …
E Jäger, M Ringhoffer, J Karbach, M Arand, F Oesch, A Knuth
International Journal of Cancer 66 (4), 470-476, 1996
3521996
Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction
JANG HENGSTLER, D Utesch, P Steinberg, KL Platt, B Diener, M Ringel, ...
Drug metabolism reviews 32 (1), 81-118, 2000
3452000
Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected
JG Hengstler, U Bolm-Audorff, A Faldum, K Janssen, M Reifenrath, ...
Carcinogenesis 24 (1), 63-73, 2003
3412003
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures
R Gebhardt, JG Hengstler, D Müller, R Glöckner, P Buenning, B Laube, ...
Drug metabolism reviews 35 (2-3), 145-213, 2003
3292003
Adverse outcome pathways: opportunities, limitations and open questions
M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ...
Archives of Toxicology 91, 3477-3505, 2017
3252017
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility
JG Hengstler, M Arand, ME Herrero, F Oesch
Genes and environment in cancer, 47-85, 1998
3071998
Of mice and models: improved animal models for biomedical research
E Bockamp, M Maringer, C Spangenberg, S Fees, S Fraser, L Eshkind, ...
Physiological genomics 11 (3), 115-132, 2002
2582002
Structure of Aspergillus niger epoxide hydrolase at 1.8 Å resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases
J Zou, BM Hallberg, T Bergfors, F Oesch, M Arand, SL Mowbray, TA Jones
Structure 8 (2), 111-122, 2000
2382000
Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways
B Oesch-Bartlomowicz, A Huelster, O Wiss, P Antoniou-Lipfert, C Dietrich, ...
Proceedings of the National Academy of Sciences 102 (26), 9218-9223, 2005
2272005
Drug-metabolizing enzymes in the skin of man, rat, and pig
F Oesch, E Fabian, B Oesch-Bartlomowicz, C Werner, R Landsiedel
Drug metabolism reviews 39 (4), 659-698, 2007
2252007
Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins: implication for the potential catalytic mechanism of …
M Arand, DF Grant, JK Beetham, T Friedberg, F Oesch, BD Hammock
FEBS letters 338 (3), 251-256, 1994
2231994
Toxico-/biokinetics of nanomaterials
R Landsiedel, E Fabian, L Ma-Hock, W Wohlleben, K Wiench, F Oesch, ...
Archives of toxicology 86, 1021-1060, 2012
2122012
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