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Kevin Chiem
Kevin Chiem
PhD Candidate, UT Health Science Center at San Antonio
Verificeret mail på livemail.uthscsa.edu
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Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice
FS Oladunni, JG Park, PA Pino, O Gonzalez, A Akhter, A Allué-Guardia, ...
Nature communications 11 (1), 6122, 2020
3222020
Contribution of SARS-CoV-2 accessory proteins to viral pathogenicity in K18 human ACE2 transgenic mice
JA Silvas, DM Vasquez, JG Park, K Chiem, A Allué-Guardia, ...
Journal of Virology 95 (17), 10.1128/jvi. 00402-21, 2021
1052021
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming
CT Wu, PV Lidsky, Y Xiao, R Cheng, IT Lee, T Nakayama, S Jiang, W He, ...
Cell 186 (1), 112-130. e20, 2023
872023
Rescue of SARS-CoV-2 from a single bacterial artificial chromosome
C Ye, K Chiem, JG Park, F Oladunni, RN Platt, T Anderson, F Almazan, ...
MBio 11 (5), 10.1128/mbio. 02168-20, 2020
872020
SARS‐CoV‐2 RBD neutralizing antibody induction is enhanced by particulate vaccination
WC Huang, S Zhou, X He, K Chiem, MT Mabrouk, RH Nissly, IM Bird, ...
Advanced Materials 32 (50), 2005637, 2020
832020
Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters
MS Piepenbrink, JG Park, FS Oladunni, A Deshpande, M Basu, S Sarkar, ...
Cell Reports Medicine 2 (3), 2021
672021
Functional evolution of the 2009 pandemic H1N1 influenza virus NS1 and PA in humans
A Nogales, L Martinez-Sobrido, K Chiem, DJ Topham, ML DeDiego
Journal of Virology 92 (19), 10.1128/jvi. 01206-18, 2018
562018
The Genetic Analysis of an Acinetobacter johnsonii Clinical Strain Evidenced the Presence of Horizontal Genetic Transfer
S Montaña, STJ Schramm, GM Traglia, K Chiem, G Parmeciano Di Noto, ...
PLoS One 11 (8), e0161528, 2016
522016
Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes
K Chiem, D Morales Vasquez, JG Park, RN Platt, T Anderson, MR Walter, ...
Journal of virology 95 (7), 10.1128/jvi. 02209-20, 2021
452021
Inhibition of Aminoglycoside 6′-N-Acetyltransferase Type Ib-Mediated Amikacin Resistance in Klebsiella pneumoniae by Zinc and Copper Pyrithione
K Chiem, BA Fuentes, DL Lin, T Tran, A Jackson, MS Ramirez, ...
Antimicrobial Agents and Chemotherapy 59 (9), 5851-5853, 2015
452015
A novel fluorescent and bioluminescent bireporter influenza A virus to evaluate viral infections
A Nogales, G Ávila-Pérez, J Rangel-Moreno, K Chiem, ML DeDiego, ...
Journal of virology 93 (10), 10.1128/jvi. 00032-19, 2019
412019
Rapid in vitro assays for screening neutralizing antibodies and antivirals against SARS-CoV-2
JG Park, FS Oladunni, K Chiem, C Ye, M Pipenbrink, T Moran, MR Walter, ...
Journal of Virological Methods 287, 113995, 2021
392021
Functional Characterization and Direct Comparison of Influenza A, B, C, and D NS1 Proteins in vitro and in vivo
A Nogales, T Aydillo, G Ávila-Pérez, A Escalera, K Chiem, R Cadagan, ...
Frontiers in Microbiology 10, 2862, 2019
352019
SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics
K Ramachandran, S Maity, AR Muthukumar, S Kandala, D Tomar, ...
IScience 25 (1), 2022
322022
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses
C Ye, K Chiem, JG Park, JA Silvas, D Morales Vasquez, J Sourimant, ...
Proceedings of the National Academy of Sciences 118 (41), e2111593118, 2021
322021
Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice
MT Mabrouk, K Chiem, E Rujas, WC Huang, D Jahagirdar, B Quinn, ...
Science advances 7 (49), eabj1476, 2021
282021
Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice. Nat Commun 11: 6122
FS Oladunni, JG Park, PA Pino, O Gonzalez, A Akhter, A Allué-Guardia, ...
272020
Restoration of susceptibility to amikacin by 8-hydroxyquinoline analogs complexed to zinc
J Magallon, K Chiem, T Tran, MS Ramirez, V Jimenez, ME Tolmasky
PLoS One 14 (5), e0217602, 2019
252019
Identification of an inhibitor of the aminoglycoside 6′-N-acetyltransferase type Ib [AAC (6′)-Ib] by glide molecular docking
K Chiem, S Jani, B Fuentes, DL Lin, ME Rasche, ME Tolmasky
MedChemComm 7 (1), 184-189, 2016
252016
Generation of recombinant SARS‐CoV‐2 using a bacterial artificial chromosome
K Chiem, C Ye, L Martinez‐Sobrido
Current protocols in microbiology 59 (1), e126, 2020
232020
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Artikler 1–20