Synthesis of Celecoxib Analogues Possessing a N-Difluoromethyl-1,2-dihydropyrid-2-one 5-Lipoxygenase Pharmacophore: Biological Evaluation as Dual … MA Chowdhury, KRA Abdellatif, Y Dong, D Das, MR Suresh, EE Knaus Journal of medicinal chemistry 52 (6), 1525-1529, 2009 | 202 | 2009 |
Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti … KRA Abdellatif, WAA Fadaly, GM Kamel, YAMM Elshaier, MA El-Magd Bioorganic chemistry 82, 86-99, 2019 | 97 | 2019 |
Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1,3,5-triarylpyrazoline and 1,5-diarylpyrazole derivatives as selective COX-2 … WAAFGMK Khaled R. A. Abdellatif, Eman K. A. Abdelall Bioorganic Medicinal Chemistry Letters 26, 406-412, 2015 | 89* | 2015 |
Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti … Z Huang, CA Velázquez, KRA Abdellatif, MA Chowdhury, JA Reisz, ... Journal of medicinal chemistry 54 (5), 1356-1364, 2011 | 85 | 2011 |
Design, synthesis and biological screening of new 4-thiazolidinone derivatives with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile KRA Abdellatif, MA Abdelgawad, HAH Elshemy, SSR Alsayed Bioorganic chemistry 64, 1-12, 2016 | 84 | 2016 |
3-Methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents HAO Khaled R. A. Abdellatif, Phoebe F. Lamie Journal of enzyme inhibition & medicinal chemistry, 2015 | 79* | 2015 |
3-Methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents HAO Khaled R. A. Abdellatif, Phoebe F. Lamie Journal of Enzyme Inhibition and Medicinal Chemistry 31 (2), 318-324, 2015 | 79* | 2015 |
Celecoxib analogs possessing a N-(4-nitrooxybutyl) piperidin-4-yl or N-(4-nitrooxybutyl)-1, 2, 3, 6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological … MA Chowdhury, KRA Abdellatif, Y Dong, G Yu, Z Huang, M Rahman, ... Bioorganic & medicinal chemistry letters 20 (4), 1324-1329, 2010 | 70 | 2010 |
New 1, 2, 4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity … WAA Fadaly, YAMM Elshaier, EHM Hassanein, KRA Abdellatif Bioorganic Chemistry 98, 103752, 2020 | 62 | 2020 |
Non-acidic 1, 3, 4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile KRA Abdellatif, WAA Fadaly, YAMM Elshaier, WAM Ali, GM Kamel Bioorganic Chemistry 77, 568-578, 2018 | 57 | 2018 |
Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2 (1H) one 5-lipoxygenase pharmacophore: Biological evaluation as dual inhibitors of cyclooxygenases and 5 … MA Chowdhury, KRA Abdellatif, Y Dong, D Das, MR Suresh, EE Knaus Bioorganic & medicinal chemistry letters 18 (23), 6138-6141, 2008 | 56 | 2008 |
Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment KRA Abdellatif, RB Bakr Medicinal Chemistry Research 30, 31-49, 2021 | 55 | 2021 |
New advances in synthesis and clinical aspects of pyrazolo [3, 4-d] pyrimidine scaffolds KRA Abdellatif, RB Bakr Bioorganic chemistry 78, 341-357, 2018 | 53 | 2018 |
Synthesis and Anticancer Activity of Some New Pyrazolo[3,4-d]pyrimidin-4-one Derivatives RRARBB Khaled R. A. Abdellatif , Eman K. A. Abdelall , Mohamed A. Abdelgawad Molecules 19, 3297-3309, 2014 | 51 | 2014 |
Synthesis of new 4-[2-(4-methyl (amino) sulfonylphenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-1, 2, 3, 6-tetrahydropyridines: A search for novel nitric oxide donor anti … MA Chowdhury, KRA Abdellatif, Y Dong, EE Knaus Bioorganic & medicinal chemistry 16 (19), 8882-8888, 2008 | 50 | 2008 |
Evaluation and optimization of pH-responsive niosomes as a carrier for efficient treatment of breast cancer HF Salem, RM Kharshoum, FI Abo El-Ela, KRA Abdellatif Drug delivery and translational research 8, 633-644, 2018 | 49 | 2018 |
Dinitroglyceryl and diazen-1-ium-1, 2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide … KRA Abdellatif, MA Chowdhury, Y Dong, D Das, G Yu, CA Velázquez, ... Bioorganic & medicinal chemistry letters 19 (11), 3014-3018, 2009 | 49 | 2009 |
Diazen-1-ium-1, 2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog … KRA Abdellatif, MA Chowdhury, Y Dong, C Velázquez, D Das, MR Suresh, ... Bioorganic & medicinal chemistry 16 (22), 9694-9698, 2008 | 47 | 2008 |
Synthesis, cyclooxygenase inhibition, antiinflammatory evaluation and ulcerogenic liability of new 1-phenylpyrazolo[3,4-d]pyrimidine derivativese AAAKRAA Rania B. Bakr Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 | 44 | 2016 |
Synthesis, cyclooxygenase inhibition, and anti-inflammatory evaluation of novel diarylheterocycles with a central pyrazole, pyrazoline, or pyridine ring GMK Khaled R. A. Abdellatif, Eman K. A. Abdelall, Wael A. A. Fadaly Medicinal Chemistry Research, 2015 | 44 | 2015 |