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Gareth P. Howell
Gareth P. Howell
Associate Principal Scientist, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Asymmetric and diastereoselective conjugate addition reactions: C–C bond formation at large scale
GP Howell
Organic Process Research & Development 16 (7), 1258-1272, 2012
1342012
Catalytic asymmetric synthesis of acyclic arrays by tandem 1, 4-addition-aldol reactions
GP Howell, SP Fletcher, K Geurts, B ter Horst, BL Feringa
Journal of the American Chemical Society 128 (46), 14977-14985, 2006
1242006
An asymmetric nitro-Mannich reaction applicable to alkyl, aryl, and heterocyclic imines
JC Anderson, GP Howell, RM Lawrence, CS Wilson
The Journal of Organic Chemistry 70 (14), 5665-5670, 2005
1142005
Asymmetric allylation of aryl aldehydes: studies on the scope and mechanism of the palladium catalysed diethylzinc mediated umpolung using phosphoramidite ligands
GP Howell, AJ Minnaard, BL Feringa
Organic & Biomolecular Chemistry 4 (7), 1278-1283, 2006
902006
Scope and limitations of the nitro-mannich reaction for the stereoselective synthesis of 1, 2-diamines
JC Anderson, AJ Blake, GP Howell, C Wilson
The Journal of Organic Chemistry 70 (2), 549-555, 2005
732005
Changes in superior mesenteric artery blood flow after oral, enteral, and parenteral feeding in humans
M Gatt, J MacFie, ADG Anderson, G Howell, BS Reddy, A Suppiah, ...
Critical care medicine 37 (1), 171-176, 2009
702009
Copper-catalyzed borylative multicomponent synthesis of quaternary α-amino esters
K Yeung, FJT Talbot, GP Howell, AP Pulis, DJ Procter
ACS Catalysis 9 (3), 1655-1661, 2019
492019
Copper‐Catalyzed Borylative Couplings with C− N Electrophiles
FJT Talbot, Q Dherbassy, S Manna, C Shi, S Zhang, GP Howell, ...
Angewandte Chemie 132 (46), 20454-20465, 2020
382020
Modular synthesis of constrained ethyl (cEt) purine and pyrimidine nucleosides
H Blade, D Bradley, L Diorazio, T Evans, BR Hayter, GP Howell
The Journal of Organic Chemistry 80 (10), 5337-5343, 2015
332015
Process design and optimization in the pharmaceutical industry: A Suzuki–Miyaura procedure for the synthesis of savolitinib
NK Adlington, LR Agnew, AD Campbell, RJ Cox, A Dobson, CF Barrat, ...
The Journal of organic chemistry 84 (8), 4735-4747, 2018
242018
Development of scalable manufacturing routes to AZD1981. Application of the Semmler–Wolff aromatisation for synthesis of the indole-4-amide core
M Sulur, P Sharma, R Ramakrishnan, R Naidu, E Merifield, DM Gill, ...
Organic process research & development 16 (11), 1746-1753, 2012
212012
Insights into the cobalt-catalyzed three-component coupling of mixed aromatic organozinc species, carbonyl compounds or imines and Michael acceptors: Synthetic and mechanistic …
J Paul, M Presset, E Le Gall, E Leonel, P Retailleau
Synthesis 50 (02), 254-266, 2018
142018
Regio-selective synthesis of 1, 2-aminoalcohols from epoxides and chlorohydrins
A Murugan, VK Kadambar, S Bachu, MR Reddy, V Torlikonda, ...
Tetrahedron Letters 53 (43), 5739-5741, 2012
132012
Modular synthesis of stereodefined benzocyclobutene derivatives via sequential Cu-and Pd-catalysis
FJT Talbot, S Zhang, B Satpathi, GP Howell, GJP Perry, GEM Crisenza, ...
ACS Catalysis 11 (23), 14448-14455, 2021
112021
Lewis acid promoted trapping of chiral aza-enolates
F Lanza, JM Pérez, RP Jumde, SR Harutyunyan
Synthesis 51 (05), 1253-1262, 2019
112019
Real-time monitoring and control of critical process impurities during the manufacture of Fostamatinib disodium
R Hart, A Herring, GP Howell, B McKeever-Abbas, N Pedge, R Woodward
Organic Process Research & Development 19 (4), 537-542, 2015
102015
Green chemistry articles of interest to the pharmaceutical industry
MC Bryan, C Dalton, A Diaz-Rodriguez, J Doerfler, OD Engl, P Ferguson, ...
Organic Process Research & Development 26 (2), 251-262, 2022
92022
A furan Diels–Alder cycloaddition approach to scyphostatin analogues
CJ Fraser, GP Howell, JPA Harrity
Organic & Biomolecular Chemistry 10 (45), 9058-9066, 2012
92012
Synthesis of 3-Oxoisoindoline-1-carboxamides through Sequential Four-Component Ugi Reaction/Oxidative Nucleophilic Substitution of Hydrogen
K Amiri, S Balalaie, MU Anwar, A Al-Harrasi
Synlett 31 (09), 861-865, 2020
42020
Regioselective Addition of Quinoline Derivatives to Carbonyl Compounds via Palladium-Catalyzed Umpolung with Diethylzinc
Y Matsumoto, K Yamamoto, M Kuriyama, K Nishida, O Onomura
Synthesis 51 (08), 1795-1802, 2019
32019
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