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Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology MA Ferreira, JM Vonk, H Baurecht, I Marenholz, C Tian, JD Hoffman, ... Nature genetics 49 (12), 1752-1757, 2017 | 506 | 2017 |
Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data I Tachmazidou, K Hatzikotoulas, L Southam, J Esparza-Gordillo, ... Nature genetics 51 (2), 230-236, 2019 | 426 | 2019 |
Exome sequencing and characterization of 49,960 individuals in the UK Biobank CV Van Hout, I Tachmazidou, JD Backman, JD Hoffman, D Liu, ... Nature 586 (7831), 749-756, 2020 | 395 | 2020 |
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ... Nature genetics 51 (3), 481-493, 2019 | 386 | 2019 |
A genome‐wide association study of autism reveals a common novel risk locus at 5p14. 1 D Ma, D Salyakina, JM Jaworski, I Konidari, PL Whitehead, AN Andersen, ... Annals of human genetics 73 (3), 263-273, 2009 | 275 | 2009 |
Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts SR Rashkin, RE Graff, L Kachuri, KK Thai, SE Alexeeff, MA Blatchins, ... Nature communications 11 (1), 4423, 2020 | 183 | 2020 |
Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food … Y Asai, A Eslami, CD van Ginkel, L Akhabir, M Wan, G Ellis, ... Journal of Allergy and Clinical Immunology 141 (3), 991-1001, 2018 | 72 | 2018 |
Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk JD Hoffman, RE Graff, NC Emami, CG Tai, MN Passarelli, D Hu, ... PLoS genetics 13 (3), e1006690, 2017 | 67 | 2017 |
Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts RE Graff, TB Cavazos, KK Thai, L Kachuri, SR Rashkin, JD Hoffman, ... Nature communications 12 (1), 970, 2021 | 60 | 2021 |
Eleven loci with new reproducible genetic associations with allergic disease risk MAR Ferreira, JM Vonk, H Baurecht, I Marenholz, C Tian, JD Hoffman, ... Journal of Allergy and Clinical Immunology 143 (2), 691-699, 2019 | 59 | 2019 |
Rare complement factor H variant associated with age-related macular degeneration in the Amish JD Hoffman, JN CookeBailey, L D'Aoust, W Cade, J Ayala-Haedo, ... Investigative ophthalmology & visual science 55 (7), 4455-4460, 2014 | 54 | 2014 |
Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas J Hoffman, L Fejerman, D Hu, S Huntsman, M Li, EM John, G Torres-Mejia, ... Breast Cancer Research 21, 1-12, 2019 | 42 | 2019 |
Electrophysiological and behavioral phenotype of insulin receptor defective mice P Das, AD Parsons, J Scarborough, J Hoffman, J Wilson, RN Thompson, ... Physiology & behavior 86 (3), 287-296, 2005 | 42 | 2005 |
The application of genetic risk scores in age-related macular degeneration: a review JN Cooke Bailey, JD Hoffman, RJ Sardell, WK Scott, MA Pericak-Vance, ... Journal of clinical medicine 5 (3), 31, 2016 | 39 | 2016 |
Association of smoking, alcohol consumption, blood pressure, body mass index, and glycemic risk factors with age-related macular degeneration: a Mendelian randomization study V Kuan, A Warwick, A Hingorani, A Tufail, V Cipriani, S Burgess, R Sofat, ... JAMA ophthalmology 139 (12), 1299-1306, 2021 | 35 | 2021 |
Age-of-onset information helps identify 76 genetic variants associated with allergic disease MAR Ferreira, JM Vonk, H Baurecht, I Marenholz, C Tian, JD Hoffman, ... PLoS genetics 16 (6), e1008725, 2020 | 34 | 2020 |
Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms NC Emami, L Kachuri, TJ Meyers, R Das, JD Hoffman, TJ Hoffmann, D Hu, ... Nature communications 10 (1), 3107, 2019 | 32 | 2019 |
Identification and Confirmation of an Exonic Splicing Enhancer Variation in Exon 5 of the Alzheimer Disease Associated PICALM Gene NC Schnetz‐Boutaud, J Hoffman, JE Coe, DG Murdock, ... Annals of human genetics 76 (6), 448-453, 2012 | 30 | 2012 |
A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma Y Asai, A Eslami, CD van Ginkel, L Akhabir, M Wan, D Yin, G Ellis, ... Journal of Allergy and Clinical Immunology 141 (4), 1513-1516, 2018 | 28 | 2018 |