| High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ... science 318 (5854), 1258-1265, 2007 | 4047 | 2007 |
| The structure and function of G-protein-coupled receptors DM Rosenbaum, SGF Rasmussen, BK Kobilka Nature 459 (7245), 356-363, 2009 | 2913 | 2009 |
| Crystal structure of the human β2 adrenergic G-protein-coupled receptor SGF Rasmussen, HJ Choi, DM Rosenbaum, TS Kobilka, FS Thian, ... Nature 450 (7168), 383-387, 2007 | 2583 | 2007 |
| Structure of a nanobody-stabilized active state of the β2 adrenoceptor SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ... Nature 469 (7329), 175-180, 2011 | 1978 | 2011 |
| GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ... science 318 (5854), 1266-1273, 2007 | 1741 | 2007 |
| Structure and dynamics of the M3 muscarinic acetylcholine receptor AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ... Nature 482 (7386), 552-556, 2012 | 909 | 2012 |
| Structure and function of an irreversible agonist-β2 adrenoceptor complex DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ... Nature 469 (7329), 236-240, 2011 | 908 | 2011 |
| Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor MP Bokoch, Y Zou, SGF Rasmussen, CW Liu, R Nygaard, ... Nature 463 (7277), 108-112, 2010 | 583 | 2010 |
| High-resolution crystal structure of the human CB1 cannabinoid receptor Z Shao, J Yin, K Chapman, M Grzemska, L Clark, J Wang, ... Nature 540 (7634), 602-606, 2016 | 414 | 2016 |
| Structure-based discovery of β2-adrenergic receptor ligands P Kolb, DM Rosenbaum, JJ Irwin, JJ Fung, BK Kobilka, BK Shoichet Proceedings of the National Academy of Sciences 106 (16), 6843-6848, 2009 | 354 | 2009 |
| Insulin resistance in polycystic ovary syndrome: decreased expression of GLUT-4 glucose transporters in adipocytes D Rosenbaum, RS Haber, A Dunaif American Journal of Physiology-Endocrinology and Metabolism 264 (2), E197-E202, 1993 | 335 | 1993 |
| Crystal structure of the human sterol transporter ABCG5/ABCG8 JY Lee, LN Kinch, DM Borek, J Wang, J Wang, IL Urbatsch, XS Xie, ... Nature 533 (7604), 561-564, 2016 | 280 | 2016 |
| Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant J Yin, JC Mobarec, P Kolb, DM Rosenbaum Nature 519 (7542), 247-250, 2015 | 230 | 2015 |
| Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes DM Rosenbaum, DR Liu Journal of the American Chemical Society 125 (46), 13924-13925, 2003 | 201 | 2003 |
| Structural and functional diversity calls for a new classification of ABC transporters C Thomas, SG Aller, K Beis, EP Carpenter, G Chang, L Chen, E Dassa, ... FEBS letters 594 (23), 3767-3775, 2020 | 194 | 2020 |
| Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane J Yin, KYM Chen, MJ Clark, M Hijazi, P Kumari, X Bai, RK Sunahara, ... Nature 584 (7819), 125-129, 2020 | 163 | 2020 |
| Structure of an allosteric modulator bound to the CB1 cannabinoid receptor Z Shao, W Yan, K Chapman, K Ramesh, AJ Ferrell, J Yin, X Wang, Q Xu, ... Nature chemical biology 15 (12), 1199-1205, 2019 | 146 | 2019 |
| Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature Structural & Molecular Biology 23 (4), 293-299, 2016 | 137 | 2016 |
| Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes P Xiao, W Yan, L Gou, YN Zhong, L Kong, C Wu, X Wen, Y Yuan, S Cao, ... Cell 184 (4), 943-956. e18, 2021 | 91 | 2021 |
| Ligand modulation of sidechain dynamics in a wild-type human GPCR LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ... Elife 6, e28505, 2017 | 87 | 2017 |
