James Birrell
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Proton coupled electronic rearrangement within the H-cluster as an essential step in the catalytic cycle of [FeFe] hydrogenases
C Sommer, A Adamska-Venkatesh, K Pawlak, JA Birrell, O Rüdiger, ...
Journal of the American Chemical Society 139 (4), 1440-1443, 2017
Mechanism of protection of catalysts supported in redox hydrogel films
V Fourmond, S Stapf, H Li, D Buesen, J Birrell, O Rüdiger, W Lubitz, ...
Journal of the American Chemical Society 137 (16), 5494-5505, 2015
Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer
JM Schuller, JA Birrell, H Tanaka, T Konuma, H Wulfhorst, N Cox, ...
Science 363 (6424), 257-260, 2019
Reactions of the Flavin Mononucleotide in Complex I: A Combined Mechanism Describes NADH Oxidation Coupled to the Reduction of APAD+, Ferricyanide, or …
JA Birrell, G Yakovlev, J Hirst
Biochemistry 48 (50), 12005-12013, 2009
Reaction Coordinate Leading to H2 Production in [FeFe]-Hydrogenase Identified by Nuclear Resonance Vibrational Spectroscopy and Density Functional Theory
V Pelmenschikov, JA Birrell, CC Pham, N Mishra, H Wang, C Sommer, ...
Journal of the American Chemical Society 139 (46), 16894-16902, 2017
Investigating the function of [2Fe–2S] cluster N1a, the off-pathway cluster in complex I, by manipulating its reduction potential
JA Birrell, K Morina, HR Bridges, T Friedrich, J Hirst
Biochemical Journal 456 (1), 139-146, 2013
Truncation of subunit ND2 disrupts the threefold symmetry of the antiporter-like subunits in complex I from higher metazoans
JA Birrell, J Hirst
FEBS letters 584 (19), 4247-4252, 2010
Investigation of NADH Binding, Hydride Transfer, and NAD+ Dissociation during NADH Oxidation by Mitochondrial Complex I Using Modified Nicotinamide …
JA Birrell, J Hirst
Biochemistry 52 (23), 4048-4055, 2013
The mitochondrial-encoded subunits of respiratory complex I (NADH: ubiquinone oxidoreductase): identifying residues important in mechanism and disease
HR Bridges, JA Birrell, J Hirst
Biochemical Society Transactions 39 (3), 799-806, 2011
Artificial Maturation of the Highly Active Heterodimeric [FeFe] Hydrogenase from Desulfovibrio desulfuricans ATCC 7757
JA Birrell, K Wrede, K Pawlak, P Rodriguez‐Maciá, O Rüdiger, ...
Israel Journal of Chemistry 56 (9-10), 852-863, 2016
Intercluster redox coupling influences protonation at the H-cluster in [FeFe] hydrogenases
P Rodríguez-Maciá, K Pawlak, O Rüdiger, EJ Reijerse, W Lubitz, ...
Journal of the American Chemical Society 139 (42), 15122-15134, 2017
Semisynthetic hydrogenases propel biological energy research into a new era
JA Birrell, O Rüdiger, EJ Reijerse, W Lubitz
Joule 1 (1), 61-76, 2017
A ternary mechanism for NADH oxidation by positively charged electron acceptors, catalyzed at the flavin site in respiratory complex I
JA Birrell, MS King, J Hirst
FEBS letters 585 (14), 2318-2322, 2011
Unique spectroscopic properties of the H-cluster in a putative sensory [FeFe] hydrogenase
N Chongdar, JA Birrell, K Pawlak, C Sommer, EJ Reijerse, O Rüdiger, ...
Journal of the American Chemical Society 140 (3), 1057-1068, 2018
Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins
Y Kutin, V Srinivas, M Fritz, R Kositzki, HS Shafaat, J Birrell, E Bill, ...
Journal of inorganic biochemistry 162, 164-177, 2016
Electrochemical Investigations on the Inactivation of the [FeFe] Hydrogenase from Desulfovibrio desulfuricans by O2 or Light under Hydrogen‐Producing Conditions
P Rodríguez‐Maciá, JA Birrell, W Lubitz, O Rüdiger
ChemPlusChem 82 (4), 540-545, 2017
Importance of Hydrogen Bonding in Fine Tuning the [2Fe-2S] Cluster Redox Potential of HydC from Thermotoga maritima
JA Birrell, C Laurich, EJ Reijerse, H Ogata, W Lubitz
Biochemistry 55 (31), 4344-4355, 2016
Spectroscopic and Computational Evidence that [FeFe] Hydrogenases Operate Exclusively with CO-Bridged Intermediates
JA Birrell, V Pelmenschikov, N Mishra, H Wang, Y Yoda, K Tamasaku, ...
Journal of the American Chemical Society 142 (1), 222-232, 2019
Sulfide Protects [FeFe] Hydrogenases From O2
P Rodríguez-Maciá, EJ Reijerse, M van Gastel, S DeBeer, W Lubitz, ...
Journal of the American Chemical Society 140 (30), 9346-9350, 2018
His-Ligation to the [4Fe–4S] Subcluster Tunes the Catalytic Bias of [FeFe] Hydrogenase
P Rodríguez-Maciá, L Kertess, J Burnik, JA Birrell, E Hofmann, W Lubitz, ...
Journal of the American Chemical Society 141 (1), 472-481, 2018
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