Stephen Aller
Stephen Aller
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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
SG Aller, J Yu, A Ward, Y Weng, S Chittaboina, R Zhuo, PM Harrell, ...
Science 323 (5922), 1718-1722, 2009
Refined structures of mouse P‐glycoprotein
J Li, KF Jaimes, SG Aller
Protein Science 23 (1), 34-46, 2014
Three-dimensional structure of the human copper transporter hCTR1
CJ De Feo, SG Aller, GS Siluvai, NJ Blackburn, VM Unger
Proceedings of the National Academy of Sciences 106 (11), 4237-4242, 2009
Projection structure of the human copper transporter CTR1 at 6-Å resolution reveals a compact trimer with a novel channel-like architecture
SG Aller, VM Unger
Proceedings of the National Academy of Sciences 103 (10), 3627-3632, 2006
The membrane protein FeoB contains an intramolecular G protein essential for Fe (II) uptake in bacteria
TC Marlovits, W Haase, C Herrmann, SG Aller, VM Unger
Proceedings of the National Academy of Sciences 99 (25), 16243-16248, 2002
Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function
SG Aller, ET Eng, CJ De Feo, VM Unger
Journal of Biological Chemistry 279 (51), 53435-53441, 2004
Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR …
RW Lehrich, SG Aller, P Webster, CR Marino, JN Forrest
The Journal of clinical investigation 101 (4), 737-745, 1998
A structural perspective on copper uptake in eukaryotes
CJ De Feo, SG Aller, VM Unger
Biometals 20 (3), 705-716, 2007
Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland
SG Aller, ID Lombardo, S Bhanot, JN Forrest Jr
American Journal of Physiology-Cell Physiology 276 (2), C442-C449, 1999
Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics
L Pan, SG Aller
Scientific reports 5 (1), 1-10, 2015
Cyclooxygenase cloning in dogfish shark, Squalus acanthias, and its role in rectal gland Cl secretion
T Yang, SJ Forrest, N Stine, Y Endo, A Pasumarthy, H Castrop, S Aller, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2002
Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias
S Waldegger, B Fakler, M Bleich, P Barth, A Hopf, U Schulte, AE Busch, ...
Pflügers Archiv 437 (2), 298-304, 1999
Mercury and zinc differentially inhibit shark and human CFTR orthologues: involvement of shark cysteine 102
GJ Weber, AP Mehr, JC Sirota, SG Aller, SE Decker, DC Dawson, ...
American Journal of Physiology-Cell Physiology, 2006
Mercury toxicity in the shark (Squalus acanthias) rectal gland: apical CFTR chloride channels are inhibited by mercuric chloride
MA Ratner, SE Decker, SG Aller, G Weber, JN Forrest Jr
Journal of Experimental Zoology Part A: Comparative Experimental Biology 305 …, 2006
Cadmium disrupts the signal transduction pathway of both inhibitory and stimulatory receptors regulating chloride secretion in the shark rectal gland
JN Forrest Jr, SG Aller, SJ Wood, MA Ratner, JK Forrest, GG Kelley
Journal of experimental Zoology 279 (5), 530-536, 1997
In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display
C Skamel, SG Aller, A Bopda Waffo
PloS one 9 (11), e113069, 2014
Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein
CA Le, DS Harvey, SG Aller
IUCrJ 7 (4), 663-672, 2020
Allosteric role of substrate occupancy toward the alignment of P-glycoprotein nucleotide binding domains
L Pan, SG Aller
Scientific reports 8 (1), 1-14, 2018
Evaluation of 1, 2, 3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809
JE Doiron, CA Le, BK Ody, JB Brace, SJ Post, NL Thacker, HM Hill, ...
Chemistry (Weinheim an der Bergstrasse, Germany) 25 (14), 3662, 2019
Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites
CD Radka, LJ DeLucas, LS Wilson, MB Lawrenz, RD Perry, SG Aller
Acta Crystallographica Section D: Structural Biology 73 (7), 557-572, 2017
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